A5085420784- Musculoskeletal pain and rehabilitation
- Pain Mechanisms and Treatments
- Opioid Use Disorder Treatment
- Spine and Intervertebral Disc Pathology
- Pain Management and Opioid Use
- Pharmaceutical Practices and Patient Outcomes
- Pain Management and Placebo Effect
- Mental Health and Patient Involvement
- Pediatric Pain Management Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Education and Admissions
- Neuroscience and Neuropharmacology Research
- Meta-analysis and systematic reviews
- Ion channel regulation and function
- Healthcare and Venom Research
- Cardiac pacing and defibrillation studies
- Shoulder Injury and Treatment
- Acupuncture Treatment Research Studies
- Botulinum Toxin and Related Neurological Disorders
- Social Media in Health Education
- Clinical practice guidelines implementation
- Focus Groups and Qualitative Methods
- Health Policy Implementation Science
- Health Systems, Economic Evaluations, Quality of Life
- Pituitary Gland Disorders and Treatments
Keele University
2017-2025
Midlands Partnership NHS Foundation Trust
2020-2025
Versus Arthritis
2020-2025
Institute for Musculoskeletal Health
2024
Wellcome Library
1999
The UK government reclassified gabapentin and pregabalin as 'controlled drugs' from April 2019. This study aimed to describe the trends in gabapentinoid prescribing before immediately after reclassification, Clinical Practice Research Datalink, an electronic primary care health record broadly representative of UK.Separately for pregabalin, we calculated annual incident prevalent rates year approval (April 1997 2004 respectively) September 2019, monthly (October 2017-September 2019)....
Growing evidence from pharmacovigilance data and postmortem toxicology reports highlights the misuse potential of gabapentinoids. This study aimed to investigate risk serious adverse outcomes (drug misuse, overdose, major trauma), their factors, in primary care patients who are prescribed Using UK Clinical Practice Research Datalink, a matched cohort calculated event rates separately for gabapentinoid-exposed unexposed cohorts. In exposed cohort, exposure range factors were calculated. Event...
Understanding patients' experiences is important when developing interventions for people living with persistent pain. Interviews and focus groups are frequently used to capture beliefs, views, perspectives. These methods often require a commitment predetermined date time that may present barrier participation. An asynchronous online discussion forum, specifically designed research purposes, provides an alternative potentially more accessible method In this article we discuss bespoke the...
ABSTRACT Background Stakeholder involvement is a core element of the Medical Research Council (MRC) framework for developing and evaluating complex interventions, but approaches to involve stakeholders are not well‐reported. We outline how contributed co‐designing Proactive clinical Review patients taking Opioid Medicines long‐term persistent Pain led by Pharmacists working in primary care Teams (the PROMPPT intervention—a review pharmacist training package). Methods brought key together...
Background Opioids are frequently prescribed for persistent non-cancer pain despite limited evidence of long-term effectiveness and risk harm. Evidence-based interventions to address inappropriate opioid prescribing lacking. Aim To explore perspectives people living with understand barriers facilitators in reducing opioids the context a pharmacist-led primary care review, identify review components features optimal delivery. Design & setting A multi-method qualitative study undertaken...
Introduction Musculoskeletal shoulder pain is a common reason for people to be treated in physiotherapy services, but diagnosis can difficult and often does not guide treatment or predict outcome. People with cite need clear information, timely, tailored consultations their pain. This trial will evaluate the introduction of personalised guided consultation help physiotherapists manage care individuals Methods analysis cluster randomised controlled clinical cost-effectiveness introducing...
Abstract Background Given the poor long-term effectiveness of opioids for persistent non-cancer pain, and their potential harm, evidence-based interventions to address opioid overprescribing pain are needed. This study aimed explore acceptability feasibility a primary care practice pharmacist-led intervention (PROMPPT review) patients prescribed evaluating PROMPPT in definitive trial. Methods A single-arm study, with mixed methods process evaluation, was conducted four English practices....
Introduction Musculoskeletal shoulder pain is a common reason for people to be treated in physiotherapy services, but diagnosis can difficult and often does not guide treatment or predict outcome. People with cite need clear information, timely, tailored consultations their pain. This trial will evaluate the introduction of personalised guided consultation help physiotherapists manage care individuals Methods analysis cluster randomised controlled clinical cost-effectiveness introducing...
Objectives: Little is known about the epidemiology of neuropathic pain in primary care patients consulting with low back-related leg pain. We aimed to describe prevalence, characteristics, and clinical course without pain, their family doctor United Kingdom. Materials Methods: This was a prospective cohort study. Data were collected using standardized baseline examination self-report questionnaires at baseline, 4, 12, 36 months. identified cases 3 definitions: 2 based on diagnosis (sciatica,...
Introduction Regular review of patients prescribed opioids for persistent non-cancer pain (PCNP) is recommended but not routinely undertaken. The PROMPPT (Proactive clinical Review taking Opioid Medicines long-term Pain led by Pharmacists in primary care Teams) research programme aims to develop and test a pharmacist-led (PROMPPT) reduce inappropriate opioid use care. This study explored the acceptability proposed inform early intervention development. Methods Interviews ( n = 15) an online...
This prospective cohort study investigates the prognosis of patients with neuropathic low back-related leg pain consulting in UK primary care. Data from 511 were collected using standardised baseline clinical examinations (including magnetic resonance imaging scan findings), self-report questionnaires at baseline, 4 months, 12 and 3 years. Cases possible (NP) persistent-NP identified either 2 definitions: 1) diagnosis sciatica, 2) version leeds assessment for neurological symptoms signs...
<title>Abstract</title> <bold>Background:</bold> Given the poor long-term effectiveness of opioids for persistent non-cancer pain, and their potential harm, evidence–based interventions to address opioid overprescribing pain are needed. This study aimed explore acceptability feasibility a primary care practice pharmacist-led intervention (PROMPPT review) patients prescribed evaluating PROMPPT in definitive trial. <bold>Methods:</bold> A single arm study, with mixed methods process...