A5022918429- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Herpesvirus Infections and Treatments
- Ophthalmology and Visual Impairment Studies
- Glaucoma and retinal disorders
- Intraocular Surgery and Lenses
- Ocular Infections and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Corneal Surgery and Treatments
- Cytomegalovirus and herpesvirus research
- Retinal and Optic Conditions
- Immunotherapy and Immune Responses
- HIV Research and Treatment
- Retinal Diseases and Treatments
- Allergic Rhinitis and Sensitization
- Syphilis Diagnosis and Treatment
- Marriage and Sexual Relationships
- Hepatitis B Virus Studies
- Virus-based gene therapy research
- Reproductive tract infections research
- Peripheral Neuropathies and Disorders
- Systemic Lupus Erythematosus Research
- Immune Response and Inflammation
- Retinal and Macular Surgery
- T-cell and Retrovirus Studies
Pepose Vision Institute
2014-2025
University of Missouri–St. Louis
2005-2019
Washington University in St. Louis
2002-2018
Marshall B. Ketchum University
2018
Vance Thompson Vision
2018
Durrie Vision
2018
PerkinElmer (United States)
2015
St. Louis County Missouri
2015
Institut de la Vision
2002-2013
Georgetown University
1988-2012
A prospective, multisite clinical study (10 sites in the European Union and United States) evaluated utility of commonly used tests tear osmolarity for assessing dry eye disease severity.Three hundred fourteen consecutive subjects between ages 18 82 years were recruited from general patient population, 299 which qualified with complete datasets. Osmolarity testing, Schirmer test without anesthesia, film breakup time (TBUT), corneal staining, meibomian dysfunction assessment, conjunctival...
Although anatomical barriers and soluble mediators have been implicated in immune privilege, it appears that the apoptotic cell death of Fas+ cells by tissue-associated CD95 ligand (Fas ligand, FasL) is an important component. One clinical example function privileged site success human corneal transplants, where a very high percentage transplants accept without tissue matching or immunosuppressive therapy. Since mouse cornea expresses abundant Fas privilege has these we examined role FasL...
To study the theoretical optical performance of 3 intraocular lens (IOL) designs in presence IOL decentration.Optics Center, Bausch & Lomb, Rochester, New York, USA.A ray-tracing program was used to evaluate effect decentration on silicone IOLs (LI61U, Lomb; Tecnis Z9000, Advanced Medical Optics; and a new aberration-free [SofPort AO, Lomb]) an experimental model eye. The done using pupil diameters 3.0 mm, 4.0 5.0 mm decentrations 0 0.25 0.50 0.75 1.00 mm. modulation transfer functions were...
Purpose: To evaluate the efficacy of commonly used biomarkers in dry eye disease management a longitudinal observational case series study followed by an interventional subset subjects treated with cyclosporine A (0.05%). Methods: Bilateral tear osmolarity, Schirmer, film breakup time (TBUT), staining, meibomian grading, and Ocular Surface Disease Index were measured for period 3 consecutive months participants recruited from clinic-based population at 2 sites. Fifty-two completed (n = 16...
To compare intraocular pressure (IOP) and corneal biomechanical metric changes after myopic laser in situ keratomileusis laser-assisted subepithelial keratectomy (LASEK).Private practice, St. Louis, Missouri, USA.The IOP, markers, Ocular Response Analyzer (ORA) waveform parameters were prospectively measured preoperatively 6 months ablation-matched LASIK eyes (mLASIK group) LASEK (mLASEK group). A retrospectively identified cohort of low myopia (lmLASIK fellow unoperated (control) tested at...