A5061964997- Flame retardant materials and properties
- Synthesis and properties of polymers
- Dendrimers and Hyperbranched Polymers
- biodegradable polymer synthesis and properties
- Photochromic and Fluorescence Chemistry
- Polymer composites and self-healing
- Natural Fiber Reinforced Composites
- Supramolecular Self-Assembly in Materials
- Nanoplatforms for cancer theranostics
- Advanced Polymer Synthesis and Characterization
- Gas Sensing Nanomaterials and Sensors
- Chemical Synthesis and Reactions
- Photoacoustic and Ultrasonic Imaging
- Polymer Surface Interaction Studies
- Synthesis of Indole Derivatives
- Photopolymerization techniques and applications
- Wound Healing and Treatments
- Supramolecular Chemistry and Complexes
- Tracheal and airway disorders
- Synthesis and characterization of novel inorganic/organometallic compounds
- Cerebral Venous Sinus Thrombosis
- Mesoporous Materials and Catalysis
- Micro and Nano Robotics
- Synthesis of Organic Compounds
GAIKER Technology Centre
2022-2023
Johannes Kepler University of Linz
2013-2022
A photolabile ruthenium-based complex, [Ru(bpy)2 (4AMP)2 ](PF6 )2 , (4AMP=4-(aminomethyl)pyridine) is incorporated into polyurea organo- and hydrogels via the reactive amine moieties on photocleavable 4AMP ligands. While showing long-term stability in dark, cleavage of pyridine-ruthenium bond upon irradiation with visible or near-infrared (in a two-photon process) leads to rapid de-gelation supramolecular gels, thus enabling spatiotemporal micropatterning by photomasking pulsed NIR-laser irradiation.
ABSTRACT The synthesis of a series novel, water‐soluble poly(organophosphazenes) prepared via living cationic polymerization is presented. degradation profiles the polyphosphazenes are analyzed by GPC, 31 P NMR spectroscopy, and UV–Vis spectroscopy in aqueous media show tunable rates ranging from days to months, adjusted subtle changes chemical structure polyphosphazene. Furthermore, it observed that these polymers demonstrate pH‐promoted hydrolytic behavior, with remarkably faster rate at...
Overproduction of reactive oxygen species (ROS) is often related to inflammation or cancer and can cause tissue damage. Probes that have been previously reported image ROS typically rely on imaging techniques low depth penetration in tissue, thus limiting their use superficial disease sites. We report herein a novel formulation hybrid nanogels loaded with gold nanoparticles (AuNP) produce contrast for computed tomography (CT) photoacoustics (PA), both being deep-tissue techniques. The...
Oxidation responsive polymers with triggered degradation pathways have been prepared via attachment of self-immolative moieties onto a hydrolytically unstable polyphosphazene backbone. After controlled main-chain growth, postpolymerization functionalization allows the preparation stable poly(organo)phosphazenes decorated phenylboronic ester caging group. In oxidative environments, cleavage group is followed by self-immolation, exposing glycine-substituted which subsequently undergoes to...
Abstract Photo‐polymerizable scaffolds are designed and prepared via short chain poly(organo)phosphazene building blocks bearing glycine allylester moieties. The polyphosphazene was combined with a trifunctional thiol divinylester in various ratios, followed by thiol‐ene photo‐polymerization to obtain porous matrices. Degradation studies under aqueous conditions showed increasing rates correlation the content. Preliminary cell show non‐cytotoxic nature of polymers their degradation products,...
Using living cationic polymerization, a series of polyphosphazenes is prepared with precisely controlled molecular weights and narrow polydispersities. As well as varying chain length through the use amine-capped polyalkylene oxide (Jeffamine) side chains varied lengths are grafted to polymer backbone give polymers dimensions. Dynamic light scattering size exclusion chromatography used confirm preparation variety dimensions thus hydrodynamic volumes. Furthermore, it demonstrated how number...
Abstract A simple supramolecular crosslinked gel is reported with a photosensitive ruthenium bipyridine complex functioning as crosslinker and poly(4‐vinylpyridine) (P4VP) macromolecular ligand. Irradiation of the organogels in H 2 O/MeOH visible NIR light (in multiphoton process) leads to cleavage pyridine moieties from breaking cross‐links causing degelation hence solubilization P4VP chains. Real‐time (RT) photorheology experiments thin films showed rapid several seconds, whereas larger...
Abstract Polymers that, upon photochemical activation with visible light, undergo rapid degradation to small molecules are described. Through functionalization of a polyphosphazene backbone pendant coumarin groups sensitive polymers which stable in the dark could be prepared. Upon irradiation, cleavage moieties exposes carboxylic acid along polymer backbone. The subsequent macromolecular photoacid is found catalyze hydrolytic Water‐soluble and non‐water‐soluble reported, due their...
The design and study of efficient polymer-based drug delivery systems for the controlled release anticancer drugs is one pillars nanomedicine. fight against metastatic invasive cancers demands therapeutic candidates with increased selective toxicity towards malignant cells, long-term activity reduced side effects. In this sense, polyphosphazene nanocarriers were synthesized sustained camptothecin (CPT) epirubicin (EPI). Linear poly(dichloro)phosphazene was modified lipophilic tocopherol or...
The current concerns of both society and materials industries about the environmental impact thermoset composites, as well new legislation, have led scientific sector to search for more sustainable alternatives reduce composites. Until now, a large extent, reinforcements been used manufacture composites thus contribute reduction pollutants. However, in recent years, developed such thermosetting resins with bio-based content and/or systems recyclable amines vitrimers that enable...
Summary A series of polyphosphazenes with molecular brush type structures have been prepared controlled weights and narrow polydispersities. The polymers show lower critical solution temperatures (LCST) between 18 90 °C, which can be easily tailored by choice side‐substituent to suit the required application. temperature triggered self‐assembly is observed give stable colloidal aggregates dimensions in region 100–300 nm.
Herein, we present the design, synthesis, and characterization of fully degradable, hybrid, star-branched dendritic polyols. First multiarmed polyphosphazenes were prepared as a scaffold which upon functionalization produced globular branched hydroxyl-functionalized polymers with over 1700 peripheral functional end groups. These polyols unique architectures could be controlled molecular weights relatively narrow dispersities. Furthermore, are shown to undergo hydrolytic degradation low...
Abstract Der lichtempfindliche Rutheniumkomplex [Ru(bpy) 2 (4AMP) ](PF 6 ) (4AMP=4‐(Aminomethyl)pyridin) wurde über die reaktiven Aminogruppen der durch Licht abspaltbaren 4AMP‐Liganden in Polyharnstoff‐Organo‐ oder ‐Hydrogele eingebaut. Im Dunkeln sind diese Gele sehr stabil. Durch Bestrahlen mit sichtbarem NIR‐Strahlung (letzteres mittels Zweiphotonenabsorption) werden Ruthenium‐Pyridin‐Bindungen gespalten, was zum Abbau des supramolekularen Gels führt. Dies ermöglicht eine räumlich und...
Abstract The incorporation of an extraneous on–off braking system is necessary for the effective motion control next generation micrometer‐sized motors. Here, design and synthesis micromotors reported based on mesoporous silica particles containing bipyridine groups, introduced by cocondensation, entrapping catalytic cobalt(II) ions within mesochannels, functionalized surface with silane‐derived temperature responsive bottle‐brush polyphosphazene. Switching polymers in a narrow window 25–30...
The synthesised polyphosphazene-based nanocarriers allowed sustained diosgenin and brassinosteroid release over 4 days, with strong to moderate MCF-7 cytotoxicity good agrochemical activity at medium low concentrations.
The introduction of polymer matrix composites in large structural parts for aircraft, buses, trains, and wind turbine blades has significantly boosted their efficiency. This is mainly due to the significant reduction weight, resulting fuel savings a on environmental impact. annual use these products around 110.000 tonnes carbon fibre composite 4.5 million glass fibre, with an average lifetime 15 years. Nevertheless, it should be noted that have high recycling disadvantages. Therefore,...