A5101217428- Advanced biosensing and bioanalysis techniques
- Plant Pathogens and Fungal Diseases
- Supramolecular Self-Assembly in Materials
- Luminescence and Fluorescent Materials
- Antimicrobial Peptides and Activities
- Ferrocene Chemistry and Applications
- Chemical Synthesis and Analysis
- Nanocluster Synthesis and Applications
- Cancer Cells and Metastasis
- Wnt/β-catenin signaling in development and cancer
- Mycotoxins in Agriculture and Food
- Cancer-related gene regulation
- Advanced Nanomaterials in Catalysis
- Click Chemistry and Applications
- Peptidase Inhibition and Analysis
- Plant-Microbe Interactions and Immunity
- Polydiacetylene-based materials and applications
- Fungal Biology and Applications
- Mycorrhizal Fungi and Plant Interactions
Center for Life Sciences
2024
Tsinghua University
2024
Fujian Agriculture and Forestry University
2023
State Key Laboratory of Chemical Engineering
2020-2022
Tianjin University
2020-2022
In this study, peptide-gold nanoclusters with tunable fluorescence were prepared by a simple "one-pot" method, which used for gene localization and delivery in vivo to achieve efficient intracellular colocalization, uptake, transfection. The efficiency of pDNA transfection was up 70.6%, there no obvious cytotoxicity. This study proves that the simple-composition bio-friendly are promising carriers can provide powerful theoretical experimental basis application peptide-metal nanocomplexes...
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The growing enthusiasm to mimic the luminous properties of fluorescent proteins (FPs) has expanded include potential biomedical applications FP analogues. We developed a series non-fluorescent oligopeptides (Fc-(X)n; where X = F, Y, W, and H; n 1–3) that can aggregate into nanoparticles with rainbow colors, termed peptidyl kit (PRK). PRK encompasses full visible color spectrum, its photoluminescent may have originated from aggregation-induced emission (AIE). Intermolecular forces restricted...
Signal peptidase (SPase) is responsible for cleavage of N-terminal signal peptides in most secretory precursor proteins and many membrane during maturation. In this study, we identified four components the SPase complex (FoSec11, FoSpc1, FoSpc2, FoSpc3) banana wilt fungal pathogen Fusarium odoratissimum. We proved that interactions exist among subunits by bimolecular fluorescence complementation (BiFC) affinity purification mass spectrometry (AP-MS) assays. Among genes, FoSPC2 was...
Abstract Owing to their good biocompatibility, flexible structure, and ease of assembling, peptide nanomaterials have become one the excellent candidates for construction fluorescent molecules attracted much attention in field biomedicine. Inspired by green protein its mutants, a series dipeptide derivatives are designed. The dipeptides aggregate into nanoparticles bind together intermolecular forces produce multicolor fluorescence. Aromatic stacking hydrogen bond networks may cause residues...