A5083093895- Dental Implant Techniques and Outcomes
- Facial Trauma and Fracture Management
- Head and Neck Cancer Studies
- Reconstructive Surgery and Microvascular Techniques
- Periodontal Regeneration and Treatments
- Bone Tissue Engineering Materials
- Oral health in cancer treatment
- Facial Nerve Paralysis Treatment and Research
- Craniofacial Disorders and Treatments
- Cleft Lip and Palate Research
- Facial Rejuvenation and Surgery Techniques
- Reconstructive Facial Surgery Techniques
- Mesenchymal stem cell research
- Bone Tumor Diagnosis and Treatments
- Cancer Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Cancer Cells and Metastasis
- Dental Radiography and Imaging
- Spinal Fractures and Fixation Techniques
- Surgical Simulation and Training
- Heterotopic Ossification and Related Conditions
- Electrospun Nanofibers in Biomedical Applications
- Sarcoma Diagnosis and Treatment
- Anatomy and Medical Technology
- Traumatic Brain Injury and Neurovascular Disturbances
Medizinische Hochschule Hannover
2015-2024
Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie
2015-2022
University of Pennsylvania
2002
<b><i>Background:</i></b> Posttherapeutic mucositis is a common secondary effect of oral cancer treatment. Mucositis affects the mucosa, which leads to specific physical impairments in function and negative impact on quality life. <b><i>Objective:</i></b> To evaluate associated with their posttherapeutic <b><i>Methods:</i></b> A retrospective analysis was conducted 1,652 patients treated for during multicenter...
Reconstruction of critical size bone defects represents a major challenge in orthopaedic surgery. Insufficient angiogenesis is limiting factor for engraftment large-scale tissue transplants. Transplantation or stimulation local mesenchymal stem cells (MSCs) potential solution to enhance angiogenesis. We recently identified angiogenic properties the Toll-like receptor (TLR) 2/6 agonist MALP-2 and now investigated if could be used stimulate MSCs order promote vitro vivo. Human from marrow...
Background/Aim: We evaluated survival rates in surgically-treated oral and oropharyngeal squamous cell carcinoma patients at our clinic, determined whether differed by tumour locations. Patients Methods: In a retrospective study, lesions 1,486 were categorized into 6 groups according to location. Patients9 age, sex, tumour-node-metastasis classification, resection status, 5-year disease-specific statistically analysed between groups. Results: A significantly inferior lower for tumours...
Abstract Purpose Dental restoration in cleft lip and palate (CLP) patients is demanding often results bone loss dental implant failure. Furthermore, unfavorable conditions of hard soft tissues as well skeletal deformities aggravate surgical treatment. Therefore, this study was designed to assess the feasibility using a new type patient-specific (IPS-preprosthetic®) CLP patients. Methods Of 63 who received IPS-preprosthetic® Department Oral Maxillofacial Surgery at Hannover Medical School,...
The aim was to compare osseointegration of blood perfused beta-tricalcium phosphate cylinders (beta-TCPB) with similar composites that were additionally loaded cancellous bone and marrow (beta-TCPB/BM/CB) for mandibular reconstruction.Twelve German Black-Headed sheep an average weight 72.5 +/- 10 kg underwent segmental resection the right hemi-mandible. animals assigned group A (n = 6) reconstructed using beta-TCPB while B received beta-TCPB/BM/CB grafts. Tissue quality histologically...
Objectives: CD133 is considered a cancer stem cell (CSC) marker in various malignancies; however, its role as biomarker of malignant melanoma remains controversial. The present study was conducted to evaluate the suitability surface antigen CSC melanoma. Methods: Human cells were fractionally separated by magnetic separation depending on phenotype and transplanted into immunodeficient mice their tumorigenic capacity. Furthermore, time until development palpable tumor growth rate measured,...
Patients undergoing ablative tumor surgery of the midface are faced with functional and esthetic issues. Various reconstructive strategies, such as implant-borne obturator prostheses or microvascular tissue transfer, currently available for dental rehabilitation. The present study shows first follow-up patients treated patient-specific implants (IPS Implants® Preprosthetic) rehabilitation extended maxillary defects following surgery.All patient specific due to postablative were included. 20...