A5032590935- Infective Endocarditis Diagnosis and Management
- Innovations in Medical Education
- Hospital Admissions and Outcomes
- Antimicrobial Resistance in Staphylococcus
- Smoking Behavior and Cessation
- Streptococcal Infections and Treatments
- Urticaria and Related Conditions
- Ultrasound in Clinical Applications
- Poisoning and overdose treatments
- Pleural and Pulmonary Diseases
- Primary Care and Health Outcomes
- Healthcare Policy and Management
- Emergency and Acute Care Studies
- Otolaryngology and Infectious Diseases
- Radiology practices and education
- Pneumocystis jirovecii pneumonia detection and treatment
- Clinical Reasoning and Diagnostic Skills
- Forensic Fingerprint Detection Methods
- Pharmaceutical studies and practices
- Coal Properties and Utilization
- Organizational Change and Leadership
- Travel-related health issues
- Forensic Toxicology and Drug Analysis
- Music Therapy and Health
- Leadership and Management in Organizations
University of Kentucky
2016-2024
Royal London Hospital
2024
University College London
2024
Lexington VA Health Care System
2017-2021
London North West Healthcare NHS Trust
2021
Northwick Park Hospital
2021
King's College Hospital
2020
Chelsea and Westminster Hospital NHS Foundation Trust
2020
University of Leicester
2019
King's College Hospital NHS Foundation Trust
2018
The EURO-ENDO registry aimed to study the management and outcomes of patients with infective endocarditis (IE).Prospective cohort 3116 adult (2470 from Europe, 646 non-ESC countries), admitted 156 hospitals in 40 countries between January 2016 March 2018 a diagnosis IE based on ESC 2015 diagnostic criteria. Clinical, biological, microbiological, imaging [echocardiography, computed tomography (CT) scan, 18F-fluorodeoxyglucose positron emission tomography/computed (18F-FDG PET/CT)] data were...
Although the BRAF V600E base substitution is an approved target for inhibitors in melanoma, gene fusions have not been investigated as anticancer drug targets. In our study, a wide variety of tumors underwent comprehensive genomic profiling hundreds known cancer genes using FoundationOne™ or FoundationOne Heme™ assays. involving intact in-frame kinase domain were observed 55 (0.3%) 20,573 tumors, across 12 distinct tumor types, including 20 novel fusions. These comprised 29 unique 5' fusion...
ObjectivesOur objective was to systematically investigate false-negative histidine-rich protein 2 rapid diagnostic tests (HRP2-RDT) in imported Plasmodium falciparum malaria cases from travelers the UK and Republic of Ireland (RoI).MethodsFive travellers returning RoI East Africa were reported PHE Malaria Reference Laboratory as negative according (HRP2)-RDT. The investigated using microscopic, RDT, molecular, genomic, vitro approaches.ResultsIn each case, HRP2-RDT negative, whereas...
Abstract The Tennessee Bureau of Investigation (TBI) serves all 95 counties Tennessee, but the data included in this article are primarily focused Upper East and (the parts state eastern time zone). forensic chemistry (seized drug) unit TBI began reporting nitazene analogues late 2019. primary found cases were isotonitazene metonitazene. After discussion review statistics, toxicology to monitor for these compounds samples by using ion characteristics with analogues. Between March 2021...
Abstract Background The clinical demands for hospitalist groups have grown at academic medical centers, without similar growth of teaching opportunities faculty. Traditional resident teams are often crowded with learners which can limit acting intern (or subintern) patient encounters. Medical students placed on nonresident teams, although there few studies learner experience a team model. Methods To address these concerns, we created two composed one attending and interns. We compared the to...
Aims Prolonged QT interval on electrocardiogram (ECG) increases the risk of ventricular arrhythmia. Patients admitted to acute medical units (AMU) may be at prolongation from multiple, recognised factors. Few data exist regarding incidence or outcomes in general admissions. The aims were determine Bazett's-corrected (QTc) upon admission AMU; relationship between QTc and inpatient mortality, length stay readmission; proportion with prolonged subsequently administered interval-prolonging...
Abstract Background Tuberculosis in the UK is more prevalent people with social risk factors– e.g. previous incarceration, homelessness - and migrants from TB endemic countries. The management of infection part elimination strategies, but challenging to provide socially excluded groups evidence base for effective interventions small. Methods We evaluated a screening treatment programme provided by peer-led service (Find&Treat) working inclusion health settings (e.g. homeless hostels)...
Narrative written feedback given to students by faculty often fails identify areas for improvement and recommended actions lead this improvement. When these elements are missing, it is challenging improve medical schools use narrative in promotion decisions, guide coaching plans pass on meaningful information residency programs. Large-group development has improved feedback, but less known about individualised supplement large-group sessions. To fill gap, we built a curriculum with general...
TTE is a good starting point, but TEE indicated in patients with high pretest probability of endocarditis.
Abstract Dissimilar metal welds (DMWs) have been used successfully in many corrosive and severe service environments. In recent years, strict limitations imposed on DMW use all Current criticality guidelines for petrochemical plants demand a fit purpose re-evaluation of DMWs. implementation requires an in-depth review welding metallurgy the potential corrosion mechanisms. Success with DMWs depends largely fusion boundary morphology, dilution limits, mechanical chemical properties,...
Brain imaging should precede lumbar puncture in patients with focal neurologic deficits or immunodeficiency, altered mental status seizures during the previous week. However, can be safely done most without first obtaining brain imaging. Empiric antibiotic and
The authors declare no conflict of interest.
No, it should be done only in certain situations, for example, if pneumothorax is suspected.
<p>E-cigarettes have the potential to reduce harm caused by cigarette smoking; however, product likeability and satisfaction are important in encouraging smokers switch less harmful products. Actual use studies play a key part evaluating reduced risk of tobacco nicotine User’s puffing behaviour, including puff duration sensory effects were evaluated for two types e-cigarette device: coil-and-wick ‘pen-type’ device (Vype ePen3), ceramic block-and-plate ‘pod-type’ ePod) with 18 mg/ml...
<p>Electronic nicotine delivery systems (ENDS) have evolved substantially in the past 10 years from disposable “cig-a-likes” to rechargeable devices with refillable tanks or cartridges. It is less clear whether users’ puffing behaviour and exposure aerosol emissions has similarly altered. Here we evaluate changes topography mouth level (MLE) of users for a series commercially available ENDS. In five separate consumer studies conducted 2014 2019, eight Vuse ENDS including cig-a-likes,...