- Adsorption and biosorption for pollutant removal
- Hemoglobin structure and function
- Nanomaterials for catalytic reactions
- Neonatal Health and Biochemistry
- Advanced Photocatalysis Techniques
- Hemoglobinopathies and Related Disorders
- Lipid Membrane Structure and Behavior
- Protein Structure and Dynamics
- Click Chemistry and Applications
- Computational Drug Discovery Methods
- Supramolecular Self-Assembly in Materials
- Erythrocyte Function and Pathophysiology
- Advanced biosensing and bioanalysis techniques
- Extraction and Separation Processes
- Mass Spectrometry Techniques and Applications
- Covalent Organic Framework Applications
- Gas Sensing Nanomaterials and Sensors
- TiO2 Photocatalysis and Solar Cells
- Catalytic Processes in Materials Science
- Synthesis and biological activity
- Lysosomal Storage Disorders Research
- Analytical chemistry methods development
- Copper-based nanomaterials and applications
- Ginkgo biloba and Cashew Applications
- Sphingolipid Metabolism and Signaling
University of Ibadan
2016-2025
Bowen University
2023-2025
Ladoke Akintola University of Technology
2012-2021
University of the Gambia
2008
University of Education, Winneba
2008
University of Bonn
2007
Abstract Once removed from their natural environment, membrane proteins depend on membrane‐mimetic systems to retain native structures and functions. To this end, lipid‐bilayer nanodiscs that are bounded by scaffold or amphiphilic polymers such as styrene/maleic acid (SMA) copolymers have been introduced alternatives detergent micelles liposomes for in vitro membrane‐protein research. Herein, we show an alternating diisobutylene/maleic (DIBMA) copolymer shows equal performance SMA...
Membrane proteins usually need to be extracted from their native environment and separated other membrane components for in-depth in vitro characterization. The use of styrene/maleic acid (SMA) copolymers solubilize surrounding lipids into bilayer nanodiscs is an attractive approach toward this goal. We have recently shown that a diisobutylene/maleic (DIBMA) copolymer similarly solubilizes model cellular membranes but, unlike SMA(3:1), has mild impact on lipid acyl-chain order thermotropic...
Towards the engineering of semiconductors for improved visible light photoelectrochemical degradation organic pollutants in wastewater, we present preparation a Z-scheme heterojunction Bi2O2S and ZnO nanoparticles removal ciprofloxacin from wastewater. The Bi2O2S/ZnO nanocomposite was synthesised via an in-situ hydrothermal method deposited on FTO substrate to form photoanode. photoanodes were characterised with electron microscopy, XRD, photo-electrochemistry, photoluminescence, XPS UV/Vis...
During endocytosis, membrane components move to intraluminal vesicles of the endolysosomal compartment for digestion. At late endosomes, cholesterol is sorted out mainly by two sterol-binding proteins, Niemann-Pick protein type C (NPC)1 and NPC2. To study NPC2-mediated intervesicular transfer, we developed a liposomal assay system. (Abdul-Hammed, M., B. Breiden, M. A. Adebayo, J. O. Babalola, G. Schwarzmann, K. Sandhoff. 2010. Role endosomal lipids NPC2 in transfer fusion. Lipid Res. 51:...
We examined the effect of Niemann-Pick disease type 2 (NPC2) protein and some late endosomal lipids [sphingomyelin, ceramide bis(monoacylglycero)phosphate (BMP)] on cholesterol transfer membrane fusion. Of all lipid-binding proteins tested, only NPC2 transferred at a substantial rate, with no ceramide, GM3, galactosylceramide, sulfatide, phosphatidylethanolamine, or phosphatidylserine. Cholesterol was greatly stimulated by BMP, little strongly inhibited sphingomyelin. were also significantly...
Toxic Cr(III) which poses environmental hazard to flora and fauna was efficiently abstracted by low-cost Nauclea diderrichii seed biomass (NDS) with good sequestral capacity for this metal investigated in study. The NDS surface analyses showed that it has a specific area of 5.36 m2/g pHpzc 4.90. Thermogravimetric analysis three consecutive weight losses from 50–200°C (ca. 5%), 200–400°C 35%), >400°C 10%), corresponding external water molecules, structural molecules heat induced condensation...
EG–TiO<sub>2</sub>photoanode was applied for the photoelectrocatalytic degradation of sulfamethoxazole. Significant COD abatement obtained and route proposed.
Abstract Membrane proteins can be examined in near‐native lipid‐bilayer environments with the advent of polymer‐encapsulated nanodiscs. These nanodiscs self‐assemble directly from cellular membranes, allowing vitro probing membrane techniques that have previously been restricted to soluble or detergent‐solubilized proteins. Often, however, high charge densities existing polymers obstruct bioanalytical and preparative techniques. Thus, authors aim fabricate electroneutral—yet...
<title>Abstract</title> Water pollution by dyes remain an important problem that constantly reduces water quality, creating hazard to aquatic flora and fauna, as well terrestrial life. Although adsorption has been a favourite technique exploited remediate this growing menace due its cost-effectiveness environmental friendliness, adsorbents limited in their capacity efficiently remove emerging dye contaminants from wastewater. In work, we present efficient method improve the sequestration of...
The synthesized Mg-doped TiO<sub>2</sub> nanoparticles (NPs) are superior photocatalysts for CO<sub>2</sub> reduction. Most energetically profitable doping is obtained sites by the use of quantum chemical computations.
We report the preparation and application of a heterostructured photoelectrocatalyst comprising carbon nanoparticles (CNPs) boron codoped BiVO4 WO3 for removal an organic dye pollutant in water. The materials, synthesized by hydrothermal method, were characterized X-ray diffraction, diffuse reflectance UV-visible spectroscopy, energy-dispersive electron microscopy. catalysts immobilized on treated titanium sheets drop-casting. fabricated electrodes linear sweep voltammetry (LSV)...
Abstract Niemann-Pick type C disease is an inherited fatal disorder characterized by the accumulation of unesterified cholesterol and other lipids in endosomal/lysosomal compartment. Two independent genes responsible for this neurodegenerative have been identified, but precise functions encoded C1 (NPC1) C2 (NPC2) proteins are not yet known. We developed a cell-free assay measuring intermembrane lipid transport examined ability bovine NPC2 (bNPC2) transfer. specifically extracts from...
Using titanium dioxide (TiO2) and its modified forms for the photocatalytic reduction of CO2 production hydrogen is a promising route providing solutions to world energy demand in foreseeable future. Here, we report synthesis series efficient stable TiO2 nanoparticles with multiwalled carbon nanotubes (CNTs) via simple combined sonothermal method, followed by hydrothermal treatment. In comparison bare TiO2, synthesized CNT–TiO2 photocatalysts showed improved activities under UVA as well...
Amphiphilic copolymers that directly extract membrane proteins and lipids from cellular membranes to form nanodiscs combine the advantages of harsher mimics with those a native-like environment. Among few commercial polymers are capable forming nanodiscs, alternating diisobutylene/maleic acid (DIBMA) have gained considerable popularity as gentle UV-transparent alternatives aromatic polymers. However, their moderate hydrophobicities high electric charge densities render all existing aliphatic...
The use of medicinal plants as an alternative mean treating various diseases has drawn the attention several researchers. desire to find lasting solutions epilepsy among humans increases every day. Thus, this work was aimed at investigating potential capacity studied phytochemicals in Alsophila spinulosa against human 4-aminobutyrate-aminotransferase well predict nonbonding interactions involved complexes. In work, ten compounds with biological activities were selected and using molecular...
In this work, the biochemical activities of seven cyclic peptides were investigated using insilico approach. The materials used in work Spartan 14 for quantum chemical analysis, molecular operating environment software docking and ADMETSAR 2.0 pharmacokinetic investigation. calculated features obtained each compound explored it was observed that molecules research have potential anti-human insulin-degrading enzyme activities. Also,...