A5017735790- Nutritional Studies and Diet
- Cardiovascular Health and Disease Prevention
- Cardiac Ischemia and Reperfusion
- Lymphatic System and Diseases
- MicroRNA in disease regulation
- Mechanical Circulatory Support Devices
- Birth, Development, and Health
- Consumer Attitudes and Food Labeling
- Telomeres, Telomerase, and Senescence
- Adipokines, Inflammation, and Metabolic Diseases
- Nutrition, Genetics, and Disease
- Atherosclerosis and Cardiovascular Diseases
- Angiogenesis and VEGF in Cancer
- Inflammation biomarkers and pathways
The First Affiliated Hospital, Sun Yat-sen University
2022-2024
Sun Yat-sen University
2022-2024
Background. Sepsis-induced cardiomyopathy (SIC) is a sort of severe disease in the intensive care unit. This research focuses on exploring influence miR-340-5p SIC and its specific mechanism. Methods. Mice were administered with lipopolysaccharide (LPS) to construct animal model. intramyocardially injected Adenoassociated Virus- (AAV-) 9 containing precursor make overexpression myocardium. The expression level myocardial was evaluated by qRT-PCR. cardiac function measured echocardiography,...
Aging is an independent risk factor for heart failure (HF), and endothelial progenitor cell (EPC) function decreases with aging. Here, we further investigated whether age has a detrimental effect on circulating EPC in HF mildly reduced ejection fraction (HFmrEF) its relationship systemic inflammation. 58 HFmrEF patients were recruited. The adhesive, migrative, proliferative activities of EPCs, MAGGIC scores, plasma interleukin (IL)-17 IL-23 levels these assessed. Older had higher scores...
Background ST-segment elevation myocardial infarction (STEMI) persists to be prevalent in the elderly with a dismal prognosis. The capacity of endothelial progenitor cells (EPCs) is reduced aging. Nevertheless, influence aging on functionality EPCs STEMI not fully understood. Method This study enrolled 20 younger patients and 21 older patients. We assessed Thrombolysis Myocardial Infarction (TIMI) Global Registry Acute Coronary Events Risk (GRACE) scores two groups. Then, we detected EPC...