A5045514880- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Bioactive natural compounds
- Traditional and Medicinal Uses of Annonaceae
- Organic Light-Emitting Diodes Research
- Eicosanoids and Hypertension Pharmacology
- Pharmacogenetics and Drug Metabolism
- Plant Pathogenic Bacteria Studies
- Perovskite Materials and Applications
- Hormonal and reproductive studies
- Natural product bioactivities and synthesis
- Luminescence and Fluorescent Materials
Australian National University
2018-2022
The total synthesis of three diastereomeric matrine natural products is reported. 8-step commences with simple acyclic precursors, forms all 4 rings the tetracyclic product framework, and forges 10 20 covalent bonds target structure. A cross-conjugated triene positioned at core an branched This precursor collapses to framework through orchestrated sequence two separate intramolecular cycloadditions. subsequent, late-stage hydrogenation accompanied by strain-release redox epimerizations...
A general synthetic approach to molecular structures that are hybrids of tetraethynylethylene (TEE) and tetravinylethylene (TVE) is reported. The synthesis permits the controlled preparation many previously inaccessible structures, including examples with different substituents on each four branching arms. Most substituted TVE–TEE found be significantly more robust compounds than their unsubstituted counterparts, enhancing prospects deployment in conducting materials devices. Their...
The total synthesis of three diastereomeric matrine natural products is reported. eight-step commences with simple acyclic precursors, forms all four rings the tetracyclic product framework and forges ten twenty covalent bonds target structure. chemical adopts an unprecedented strategy that encompasses both transform stereochemical attributes. A cross-conjugated triene positioned at core branched structure, which collapses to through orchestrated sequence two intramolecular cycloadditions....