Abstract Background Intracavernous injection of mesenchymal stem cells (MSCs) is a promising method for diabetic mellitus-induced erectile dysfunction (DMED), but short survival time MSCs in cavernous fatal defect therapy. This study investigated therapeutic efficiency and potential mechanism probucol combined with MSCs. Methods In vivo study, total forty-eight 10-week-old male Sprague-Dawley (SD) rats were used. Twelve received intraperitoneal PBS as the sham group; rest 60 mg/kg...

Prostate cancer (PCa) is one of the leading causes cancer-related death in men. Blocking androgen receptor (AR) signaling an effective treatment strategy for advanced metastatic disease PCa However, method blocking AR not suitable castration-resistant prostate (CRPC), and CRPC still clinically difficult. It has recently been reported that MCT4 a plasma membrane transporter mediates secretion lactic acid from aerobic glycolysis by cells. Its expression up-regulated plays important role...

Autophagy and apoptosis have been regarded as important processes in the development of diabetic erectile dysfunction (DMED). Probucol is considered to anti-apoptotic effects, but its relationship with autophagy has not reported. The aim this study was investigate effects mechanisms probucol on function. Thirty Sprague–Dawley (SD) male rats (12 weeks old) were fasted for 12 h. Twenty SD injected a single intraperitoneal injection 60 mg kg−1 streptozotocin (STZ). Ten given vehicle only used...

Virtual Reality (VR) is gradually integrating into classroom teaching, emerging as a new trend in educational development the era of artificial intelligence. Desktop virtual reality stands out due to its lower cost and greater convenience. To elucidate effectiveness desktop learning, this paper employs meta-analysis systematically analyze 31 relevant studies. The findings suggest that can effectively enhance students' academic achievement, fostering improvements their knowledge, emotions,...

Renal cell carcinoma (RCC) is a lethal malignancy of the genitourinary system. Follistatin-like 3 (FSTL3), which mediates differentiation and growth, acts as biomarker tumors participates in cancer development progression. Presently, FSTL3's functions RCC were investigated. Quantitative reverse transcription PCR (qRT-PCR), Western Blot, enzyme linked immunosorbent assay (ELISA) conducted to verify FSTL3 expression tissues lines. BrdU CCK8 experiment made monitor proliferation. Transwell was...

Splashing is the main atomization source for a jet impinging on liquid layer. Increased understanding of splashing rainfall characteristics can help to reduce hazard flood discharge in hydraulic engineering. In this study, spatial distribution caused by nappe flow downstream water cushion was experimentally investigated. Effects factors impingement velocity, unit discharge, and water-cushion depth were The shape contours approximately elliptical horizontal planes. Maximum intensity...

To compare the impact of plasma button transurethral vapour enucleation prostate (PVEP) and plasmakinetic resection (PKRP) on lower urinary tract symptoms sexual function in patients with benign prostatic enlargement (BPE) >90 ml. Between July 2017 August 2018, 101 symptomatic BPE were randomly, prospectively assigned to either PKRP or PVEP our department. The clinical characteristics evaluated before after surgery. Post-void residual volume, IPSS QoL all significantly decreased compared...

In recent years, the promotion and application of technology-enhanced learning spaces in teaching have garnered significant attention, but effectiveness their remains controversial. This is first meta-analysis to examine on student outcomes. The study integrates data from 39 experimental quasi-experimental studies. results show that a significantly positive effect outcomes (SMD=0.62). Further analysis moderator variables such as educational stage, subject nature, knowledge type, sample size,...

On the basis of mathematical relationship between transformer inrush current and closing voltage parameters, a scheme suppress is proposed based on control amplitude angle. This adopts combination function angle, which target magnetic flux does not exceed saturation during whole no-load process. Under premise considering different remanence, analyzes tuning method parameters A three-phase model built to simulate method. The simulation results are compared with direct phase-selection scheme....

Abstract Background: Intracavernous injection of mesenchymal stem cells (MSCs) is a promising method for Diabetic mellitus-induced erectile dysfunction (DMED), but short survival time MSCs in cavernous fatal defect therapy. This study investigated therapeutic efficiency and potential mechanism probucol combined with MSCs. Methods: In vivo study, total forty-eight 10-week-old male Sprague-Dawley (SD) rats were used this study. Twelve received intraperitoneal PBS as Sham Group; the rest...

Pheochromocytomas are neuroendocrine tumors that produce catecholamines and can be difficult to diagnose. Bladder involvement is uncommon with pheochromocytoma. Hypertension (sometimes hypertensive crisis coinciding micturition), headache, hematuria syncope, which commonly associated voiding, the most prevalent symptoms. While transurethral resection may performed in roughly 20% of patients, 70% require partial cystectomy 10% radical cystectomy. We present a case pheochromocytoma...

Multiple antennas, which can significantly increase the channel capacity, is one of key technologies in next generation wireless communication systems. In this paper, we present a general multiple antenna evolution platform (GMAP), software-defined radio for implementing real-time multiple-antenna system on hybrid FPGA/DSP test-bed. Furthermore, two applications implemented GMAP are introduced: dual-antenna TD-SCDMA terminals; another MIMO with 8 transmit antennas and 4 receive antennas. (3 pages)

Renal carcinoma (RC) originates in the renal tubular epithelial system, among which cell (RCC) is most frequent one. The forkhead activin signal transducer 1 (FAST1) has been shown to interfere with tumor progression as an oncogene, while its role RC limited. Therefore, this paper explored prognostic significance, specific effects, and related mechanisms of FAST1 on RC.Cell colony formation assay, counting kit-8 (CCK8) flow cytometry Transwell assay were used test proliferation, viability,...

Objectives To evaluate the retroperitoneal laparoscopy combined with abdominal incision for radical nephroureterectomy and summarize our experience in surgery.Methods From Jul 2008 to 2012,the Clinical data were analysed 23 patients who underwent nephroureterectomy.Results All operations successful,there no conversion open surgery this series.The mean operating time was (136.4 ± 27.1) min,the blood loss (151.3 ±44.5)ml,the recovery of intestinal function (1.8 0.3)d,the drainage tube removed...

Abstract In this paper, for the innovative teaching of high school project-based courses, an adaptive differential evolutionary algorithm is used as one tools project to help students solve complex problems. The traditional evolution has problems local optimum and low convergence accuracy; overcome these limitations, paper proposes enhanced reverse learning algorithm. OL-ADE improved by introducing strategy in machine extract elite individual population from original select better-adapted...

With the advent of ultra-high-performance dedicated brain PET imaging systems, such as NeuroEXPLORER (NX), which offer high spatial resolution, sensitivity, and improved timing human motion has become a major limiting factor for quantification. This includes rigid non-rigid in head neck regions. Several data-driven methods using emission data have been previously proposed evaluated tracking. However, accuracy these is susceptible to early time frames dynamic study. Benefiting from increased...

Multiple antennas, which can significantly increase the channel capacity, is one of key technologies in next generation wireless communication systems. In this paper, we present a general multiple antenna evolution platform (GMAP), software-defined radio for implementing real-time multiple-antenna system on hybrid FPGA/DSP test-bed. Furthermore, two applications implemented GMAP are introduced: dual-antenna TD-SCDMA terminals; another MIMO with 8 transmit antennas and 4 receive

An on-line method using no-load closing impulse current of the line to discriminate CT's polarity is proposed in this paper. No-load model for single-phase transmission established firstly, and mathematical relationship between electrical quantities parameters during process described by differential equations. Line such as inductance or resistance are regarded unknown quantities, characteristics their values analyzed when solving equations under different CT polarities. Then calculation...

Abstract Background Intracavernous injection of mesenchymal stem cells (MSCs) is a promising method for Diabetic mellitus-induced erectile dysfunction (DMED), but short survival time MSCs in cavernous fatal defect therapy. This study investigated therapeutic efficiency and potential mechanism Probucol combined with MSCs. Methods In vivo study, total forty-eight 10-week-old male Sprague-Dawley (SD) rats were used this study. Twelve received intraperitoneal PBS as Sham Group; the rest 60mg/kg...