Abstract The increasing number cases of coronavirus disease (COVID-19) infections in the general population Indonesia raises questions concerning public’s knowledge and attitudes regarding this pandemic. To determine correlation between COVID-19 outbreak 1 month after first were reported Indonesia. This cross-sectional study was conducted early March end April 2020 Indonesia, beginning with North Sumatra region, where spread began. Questionnaires randomly distributed online red zone Data...

Introduction: Oxidative stress has been considered as one of many contributor in developing risk cancer. may also promote the increasing number free radical. Malondialdehyde (MDA) is radical oxidative marker, while Superoxide Dismutase (SOD) play role endogenous antioxidant. It postulated that cancer cells there an increase compared to normal cell. Method: This study a case controlled analytical find relationship between levels MDA and SOD patients with brain tumours. The sample obtained was...

Systemic inflammation in chronic obstructive pulmonary disease (COPD) contributes to multimorbidity and a diminished quality of life. Probiotics, through the gut-lung axis, have shown potential mitigate systemic inflammation; however, their specific role COPD-related remains unclear. The aim this study was evaluate efficacy probiotics reducing serum interleukin-6 (IL-6) levels by enhancing butyric acid production murine model COPD. An vivo experimental with post-test-only control group...

Objective: The objective of this study is to examine how international monetary policy shocks impact emerging markets' economic stability and policy-making through currency interconnectedness analysis, in the context SDGs. Theoretical Framework: examines financial using Diebold-Yilmaz spillover index measure shock transmission among economies effectively comprehensively. Method: methodology adopted for research employs a TVP-VAR model analyze daily exchange rate data USD pairs from six major...

Objective: This study aims to test the association between family support and coping strategies anxiety at Dr. Pirngadi General Hospital Medan. Methods: The was a correlational descriptive with cross-sectional approach. samples were 102 cancer patients undergoing chemotherapy, who selected through purposive sampling technique. Data collected using questionnaire instrument developed based on concept of House Friedman theory, strategy modified from Revised Ways Coping by Folkman Lazarus, an...

Brain tumor is one of the most devastating diseases in world. The Pathogenesis vary multiple aspect mechanism. microenvironment contains many different noncancerous cell types addition to cancer cells. Inflammation thought be factors that influence oncogenesis process brain tumors.This study a case controlled analytical analyzes relationship between levels inflammatory markers with type tumor. Samples 35 people were then categorized according variables above and analyzing measure its...

تحتوي أوراق Anredera cordifolia على مركبات كيميائية يمكن استخدامها كمضاد للسمنة.الهدف من الدراسة هو فحص مستخلص الإيثانول الخواص الكيميائية النباتية والمضادة للسمنة لأوراق cordifolia. باستخدام مذيب الإيثانول، تم استخدام عملية النقع لاستخراج التحليل الكيميائي النباتي لمستخلص للأكسدة بسبب احتوائه الفلافونويد والمركبات الفينولية والقلويدات والعفص. تحديد محتوى الفلافونويدات في المستخلصات مقياس الطيف الضوئي UV-VIS كيرسيتين، المذاب الميثانول للحصول محلول كيرسيتين بتركيز 100 جزء المليون وتم قياس...

Anemia is an abnormal hemoglobin concentration in blood that impacts almost 40% school-age children developing countries. Intestinal parasitic infection, along with malnutrition are contributed to influence absorption, transportation, and metabolism of iron which the most common etiology anemia children. The purpose this study was determine whether there a correlation between deficiency (IDA) intestinal infection generally protozoa particularly among Medan. This cross-sectional conducted...

The routine examination of vitamin D levels is carried out by checking serum 25(OH)D levels, while 1.25(OH)D are less frequently utilized. proposition that testing for salivary can show a correlation with in healthy people questionable, especially low intake. This study aimed to find the between which were assessed as and saliva, intake.This cross-sectional involving men women, aged 18-60 years, from August November, 2020, North Sumatra Province, Indonesia. parameters studied saliva serum,...

Tuberculosis (TB) remains a major public issue in Indonesia, including North Sumatra province. Despite reported good efficacy of TB treatment the region, success depends on many factors, nutritional status.To determine relationship between Body Mass Index and Albumin level with sputum conversion AFB-positive pulmonary patients.The study was done two primary health centres Medan October November 2018. A total 39 newly diagnosed patients confirmed were included study. Participants received...

During Ramadan fasting, people are likely to consume water and beverages lower than recommended intake due the limited time. However, it is necessary achieve daily maintain hydration status, as well productivity during fasting. Unfortunately, there a lack of data on drinking patterns Ramadan. This study aims investigate beverage help requirements among Indonesian adults. cross-sectional conducted period from April May 2021 (Ramadan 1442 Hijri). We used self-administered questionnaire habits...

Background: A large proportion of women living in tropical regions experience vitamin D deficiency, with lifestyle being one the predisposing factors.Women single nucleotide polymorphisms receptor gene rural and urban areas have different lifestyles.Objective: This study aimed to determine differences serum levels 25-hydroxyvitamin [25(OH)D] areas.Methodology: The present used a cross-sectional design involving 100 healthy women, who were evaluated for several parameters including 25(OH)D,...

Context: Passion fruit (Passiflora edulis Sims) is a well-known plant in the tropical islands, especially North Sumatra, Indonesia, because of its sweet and refreshing taste. Although often used as syrup sweetener, efficacy P. seed extract for anticancer activity has not been widely studied. Aims: To evaluate ability to induce cytotoxicity apoptosis HSC-2, HSC-3, MCF-7, HaCaT cell lines. Methods: was extracted by using 96% ethanol. The measured an MTT assay 48 hours. Apoptosis examined TUNEL...

Background: Low serum 25(OH)D levels often occur during the winter and spring of temperate countries due to low sun exposure but there are many other factors linked with vitamin D deficiency that can in tropical countries. Objectives: assess levels, compare difference associated factors, find independently level. Method: This cross sectional study was conducted on 156 healthy Indonesian women dry season. measured examined two single nucleotide polymorphisms receptor gene (TaqI BsmI),...

<p><strong>Aim</strong> <br />To investigate the influence of zinc supplementation on pregnant women for prevention stunting through an analysis<br />of maternal serum zinc, cord blood osteocalcin and neonatal birth length.<br /><strong>Methods</strong> />This study was conducted with pre-test/post-test control groups double-blind randomization. Patients were...

Difficulties in exercising have occurred for the entire world's population during this COVID-19 pandemic, especially second wave at end of 2021. Most worrying is lack physical activity young adults, as exercise will increase risk noncommunicable diseases future. The youth such university student can be agents change, to activity, from sedentary sport life. This study aimed determine relationship between knowledge, attitudes, and actions students correlation related variables.This a...

تهدف هذه الدراسة إلى تحديد تأثير التناول المزمن للمنشطات من نوع الأمفيتامين بجرعات متفاوتة على الالتهاب والإجهاد التأكسدي في فئران ويستار. تم إعطاؤهم ميثيلفينيديت وتم تقسيمهم 4 مجموعات علاجية. علاوة ذلك ، إجراء تجميع عشوائي بسيط لتقسيم العينات 5 تتكون كل مجموعة 9 فئران. تضمنت المجموعات الفئران التي أعطيت فقط الماء المقطر كعناصر تحكم بالإضافة تلك 10 مجم / كجم وزن الجسم و 20 40 لمدة أسابيع كمجموعات تجريبية. ثم التحليل الإحصائي باستخدام GraphPad Prism لمقارنة تأثيرات الإجهاد والالتهاب الجهازي...

Helicobacter pylori vacA and cagA genes are associated with higher virulence. Vascular Endothelial Growth Factor (VEGF) is one important marker for neo-angiogenesis.The purpose of this study was to investigate the relationship between VEGF serum levels in H. infection.A cross-sectional done on eighty patients that consecutive admitted endoscopy unit. The diagnosis infection based rapid urease test. Serum samples were obtained determine circulating level. Polymerase chain reaction examine...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Amelia R, Sari DK, Muzasti RA, Fujiati II, Wijaya H. Early detection of diabetic nephropathy based on albumin creatinine ratio (acr) in type 2 diabetes mellitus patients Medan. Indonesia. Family Medicine & Primary Care Review. 2021;23(2):135-138. doi:10.5114/fmpcr.2021.105903. APA Amelia, R., Sari, D., Muzasti, Fujiati, I., Wijaya, (2021). Review, 23(2), 135-138. https://doi.org/10.5114/fmpcr.2021.105903...

BACKGROUND: Diabetic nephropathy (ND) is one of the main complications chronic microvascular diabetes mellitus (DM) and leading cause end-stage renal disease (ESRD), accounting for nearly half all ND cases with ESRD incidence in developed countries. Recently, cystatin C serum has been considered as a new biomarker diagnosis kidney damage. Cystatin-C an appropriate marker GFR measurement because it not affected by age, weight, gender, protein intake. Early detection abnormal function...

Abstract Background: Latent Tuberculosis Infection (LTBI) on pregnant women are highly prone to progress into an active TB infection that could infect her newborn. The aforementioned progressivity is dependent the mother’s immunity system, and said immune system’s mechanism influenced by levels of vitamin D. response mother during process thought affect child’s system since pregnancy term. purpose this research find role D LTBI level neonates so we able pinpoint create adequate for both...

Smoking is the leading cause of death in worldwide and known as one risk factors development pathogenesis several diseases most are respiratory cardiovascular diseases. Secondhand smoke (SHS) exposure associated with negative health consequences including tract infection, asthma, cancer. One that has to these inflammation. Garlic (Allium sativum) a medicinal herb contains Allicin other active constituents have anti-inflammatory ability by suppressing expression production proinflammatory...

Background: Sickle Garlic (Allium sativum L.) is known as a spice native to western Asia has strong antioxidant effect and revealed it functions an by increasing ROS-capture activity, cellular antioxidants, SOD, CAT, GSH levels in cells. Cigarette smoke very dangerous because can cause serious illness death. major source of exogenous ROS its particles are high free radicals. Smoking also related decrease the body's natural levels. Glutathione (GSH) synthesis expression were found increase...