Geun Woo Lee

ORCID: 0000-0002-1459-1652
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About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • Urinary Tract Infections Management
  • Antibiotic Use and Resistance
  • Respiratory viral infections research
  • Antibiotic Resistance in Bacteria
  • SARS-CoV-2 and COVID-19 Research
  • Streptococcal Infections and Treatments
  • Lysosomal Storage Disorders Research
  • Long-Term Effects of COVID-19
  • Thermal Regulation in Medicine
  • Allergic Rhinitis and Sensitization
  • Polyamine Metabolism and Applications
  • Patient Satisfaction in Healthcare
  • Bacterial Identification and Susceptibility Testing
  • Healthcare Education and Workforce Issues
  • Mast cells and histamine
  • Lipid Membrane Structure and Behavior
  • Pharmacy and Medical Practices

Health Insurance Review and Assessment Service
2018-2025

Jeonbuk National University
2021

To investigate the association between oral antiviral administration and post-acute sequelae of COVID-19 (PASC) risk in Korea. This retrospective cohort study used data from Korea Disease Control Prevention Agency Health Insurance Review Assessment Service. We analyzed patients aged > 60 years January to December 2022. The primary outcome was occurrence 27 PASCs within 30-120 days after diagnosis. hazard ratio calculated using Cox proportional hazards model. Nirmatrelvir/ritonavir...

10.1016/j.ijid.2025.107850 article EN cc-by-nc-nd International Journal of Infectious Diseases 2025-02-01

Despite the proven effectiveness of oral antivirals against severe acute respiratory syndrome coronavirus 2 in randomized trials, their clinical reevaluation is vital context widespread immunity and milder prevalent variants. This study aimed to assess for disease 2019 (COVID-19).

10.3346/jkms.2024.39.e272 article EN cc-by-nc Journal of Korean Medical Science 2024-01-01

The prevalence of extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC) in the community has increased worldwide due to multifactorial reasons. ESBL-EC bloodstream infection (BSI) complicates decision for proper antimicrobial administration. In this multicenter study, we investigated prevalence, risk factors, and molecular background community-onset (CO) BSI.We included data all episodes BSI origin from May 2016 April 2017 obtained Korean national resistance surveillance system,...

10.3343/alm.2021.41.5.455 article EN Annals of Laboratory Medicine 2021-04-07

Abstract In the present study, we investigated pattern of changes in antibiotic prescription and antimicrobial resistance (AMR) Escherichia coli South Korea between 2007 2018. We collected data related to AMR E. from national surveillance system. used Mann–Kendall test Spearman’s correlation identify trends examine relationship them, respectively. Although noted a significant decreasing trend ampicillin gentamicin prescriptions all medical institutions, identified higher level long-term care...

10.1038/s41598-021-84450-z article EN cc-by Scientific Reports 2021-03-11

There had been concerns about the acute complications during or shortly after coronavirus disease 2019 (COVID‐19) treatment with nirmatrelvir/ritonavir (NMVr) and molnupiravir (MOL). This study aimed to compare risks of selected safety events in patients treated without NMVr MOL using COVID‐19 oral assessment data, constructed through linkage nationwide databases: National registry, Real‐time Prescription Surveillance, Health Insurance data. We identified all adults diagnosed between January...

10.1002/cpt.3461 article EN Clinical Pharmacology & Therapeutics 2024-10-08

Inappropriate antibiotic use significantly contributes to resistance, resulting in reduced efficacy and an increased burden of disease. The objective this study was investigate the characteristics prescribers whose antibiotics high explore factors affecting by medical institutions. This analyzed National Health Insurance claims data from 2015. Antibiotic prescription were terms number defined daily doses per 1,000 patients day, according World Organization anatomical-therapeutic-chemical...

10.5124/jkma.2018.61.11.687 article EN cc-by-nc Journal of Korean Medical Association 2018-01-01

Liposomes were modified using two different methods. In Method 1, liposomes by mixing whole lysosomal proteins, lipid, and cholesterol before preparation. For 2, the proteins after liposome 1-modified exhibited improved cell mortality compared to 2-modified liposomes. The then evaluated for their antimicrobial activity against enzymes, Escherichia coli did not modify surface. membrane extracted from lysosomes in Saccharomyces cerevisiae analyzed two-dimensional electrophoresis find specific...

10.1166/jbn.2018.2654 article EN Journal of Biomedical Nanotechnology 2018-10-11

Abstract Histamine is an immune mediator that mainly secreted when immediate, rapid response needed in the body, and excessive secretion of histamine or lack enzymes degrade can result various side effects. binding protein (HBP) by a mite species to prevent host’s histamine-induced responses molecule blood. Cloning was performed express HBP on yeast surface (MBTL-GWL-1), immunofluorescence (IF) western blot confirm expression recombinant protein. The inhibitory ability GWL-1 cells tested...

10.21203/rs.3.rs-915799/v1 preprint EN cc-by Research Square (Research Square) 2021-09-28
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