- Non-Invasive Vital Sign Monitoring
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Hemodynamic Monitoring and Therapy
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Blood Pressure and Hypertension Studies
- scientometrics and bibliometrics research
- Peripheral Artery Disease Management
- Meta-analysis and systematic reviews
- Academic Publishing and Open Access
- Healthcare Technology and Patient Monitoring
- Cardiovascular Syncope and Autonomic Disorders
- Biomedical and Engineering Education
- Academic integrity and plagiarism
- Respiratory Support and Mechanisms
- Quality and Safety in Healthcare
- Sperm and Testicular Function
- Biomedical Ethics and Regulation
- Artificial Intelligence in Healthcare and Education
- Ethics in Business and Education
- Reproductive Biology and Fertility
- Sleep and Wakefulness Research
- Phonocardiography and Auscultation Techniques
- Diabetic Foot Ulcer Assessment and Management
Defence Science and Technology Agency
2025
Ngee Ann Polytechnic
2011-2016
The University of Queensland
2004-2012
Agency for Science, Technology and Research
2008-2010
Nanyang Technological University
2005-2009
Singapore General Hospital
2008-2009
Singapore Institute for Clinical Sciences
2008
Queensland University of Technology
2005
Study of cardiac functions has shown to be important in understanding the prognosis and pathogenesis vascular diseases. A physiologic parameter termed pulse transit time (PTT) been studied intensively used as an indirect marker such pathologic conditions. It is defined it takes a pressure pulsation travel between two arterial sites. For convenience measurement, interval peak R-wave on electrocardiogram onset corresponding finger pad measured by photoplethysmography usually used. In this...
Undiagnosed cognitive impairment is a pervasive global issue, often due to subtle nature of early symptoms, necessitating the use brief tests for detection. However, most are not scalable (requiring trained professionals), and designed lower literacy groups (e.g. in underserved communities). Here, we developed PENSIEVE-AITM, drawing-based digital test that less dependent on literacy, can be self-administered <5 min. In prospective study involving 1758 community-dwelling individuals aged 65...
Imbalance of the human haemodynamic system can provide a prognosis syncope, dizziness or hypertension. This be assessed by monitoring its responses to postural change. Examining variations in blood pressure (BP) is deemed an effective means identify symptoms this associated condition. However, conventional methods do not promote prolonged due discomfort caused patients. Established correlations between BP and pulse wave transmission have shown usefulness clinical applications. In study,...
Pulse transit time (PTT) is a non-invasive measure of arterial compliance. It can be used to assess instantaneous blood pressure (BP) changes in continual cardiovascular measurement such as during overnight respiratory sleep studies. In these studies, periodic limb position occur randomly. However, little known about their possible effects on PTT monitored the various limbs. The objective this study was evaluate differences all four limbs two positional (lowering and raising limb). Ten...
Two important parameters that are generally under continual observation during clinical monitoring heart rate (HR) variability and breathing interval (BI) of patients. Current HR night-long childhood respiratory sleep studies is well tolerated but BI requires instrumentation, like nasal cannula, can be less accommodating for children. In this study, was extracted from the photoplethysmographic (PPG) signals using a two-stage signal processing technique termed zero-phase digital filtering....
Polysomnography (PSG) is the current standard protocol for sleep disordered breathing (SDB) investigation in children. Presently, there are limited reliable screening tests both central (CE) and obstructive (OE) respiratory events. This study compared three indices, derived from pulse oximetry electrocardiogram (ECG), with PSG gold standard. These indices were heart rate (HR) variability, arterial blood oxygen de-saturation (SaO2) transit time (PTT).15 children (12 male) routine studies...
Pulse oximetry is commonly used as an arterial blood oxygen saturation (SaO2) measure. However, its other serial output, the photoplethysmography (PPG) signal, not well studied. Raw PPG signals can be to estimate cardiovascular measures like pulse transit time (PTT) and possibly heart rate (HR). These timing-related measurements are heavily dependent on minimal variability in phase delay of signals. Masimo SET Rad-9 Novametrix Oxypleth oximeters were investigated for their characteristics...
Studies have shown that increased arterial stiffening can be an indication of cardiovascular diseases like hypertension. In clinical practice, this detected by measuring the blood pressure (BP) using a sphygmomanometer but it cannot used for prolonged monitoring. It has been established pulse wave velocity (PWV) is direct measure its usefulness hampered absence non-invasive techniques to estimate it. Pulse transit time (PTT) simple and method derived from PWV. However, limited knowledge PTT...
A simple and non-invasive technique, termed pulse transit time (PTT), has shown its potential in long-term investigations such as respiratory sleep studies cardiovascular studies. Based on these findings, the PTT technique shows relevance for continuous haemodynamic monitoring critical care. The objective of this review is to understand potential, applications limitations clinical setting. Present methods automated oscillometric blood pressure (BP) auscultatory techniques have their known...
Studies have indicated that the number and frequency of fraudulent publications being retracted are not subsiding even with greater awareness such incidents in recent decades. In this study, trends retraction period, citations coauthors 5 selected researchers who had ≥ 15 were analyzed. The obtained results shows period is 48.96 ± 32.16 months for 113 affiliated to studied researchers. There a total 180 6.40 3.26 per researcher's publication. linear regression analysis indicates there...