cis-Diammineplatinum (II) dichloride (cisplatin) is the important anti-cancer agent useful in treatment of various cancers. Unfortunately, it can produce unwanted side effects tissues, including liver. The present study investigated possible protective role curcumin and α-tocopherol against oxidative stress-induced hepatotoxicity rats upon cisplatin treatment. Male Wistar were divided into five groups (n = 5). Saline Cis groups, intraperitoneal (i.p.) injected with normal saline [20 mg/kg...

Tangerine (Citrus tangerina) is one of the most important crops Thailand with a total harvest that exceeds 100,000 tons. Citrus essential oils are widely used as aromatherapy and medicinal agents. The effect tangerine oil on human brain waves sleep activity has not been reported. In present study, we therefore evaluated these effects by measurement electroencephalography (EEG) 32 channel platforms according to international 10–20 system in 10 male female subjects. Then onset latency was...

Soil-transmitted helminth (STH) infections are among the most common type of worldwide and widely distributed in tropical areas. In rural areas southern Thailand where land is used for agriculture, children at risk acquiring parasites, especially STHs. Assessing current situation regarding parasitic infection these a prerequisite developing appropriate control measures. This study aimed determining prevalence intestinal infections, intensity STH associated factors primary schoolchildren...

In this work, we analyze the epidemic data of cumulative infected cases collected from many countries as reported by World Health Organization (WHO). Our inspection is motivated renormalization group (RG) framework. Here propose RG-inspired logistic function form an strength with n being asymmetry in modified function. We perform non-linear least-squares analysis various countries. The uncertainty for model parameters computed using squared root corresponding diagonal components covariance...

The functional food market is growing with a compound annual growth rate of 7.9%. Thai recipes use several kinds herbs. Lemongrass, garlic, and turmeric are ingredients used in curry paste. Essential oils released the preparation step create flavor fragrance famous tom yum massaman dishes. While biological activities these have been investigated, including antioxidant, anti-inflammatory, antimicrobial activities, there still lack understanding regarding responses to essential plants. To...

Essential oils are volatile fragrance liquids extracted from plants, and their compound annual growth rate is expected to expand 8.6% 2019 2025, according Grand View Research. have several domains of application, such as in the food beverage industry, cosmetics, well for medicinal use. In this study, Michelia alba essential oil was leaves rich linalool components found lavender jasmine oil. The effects inhaling michelia on human brainwaves still need be elucidated. Ten male ten female...

Ceftriaxone (CTX) exerts a neuroprotective effect by decreasing glutamate excitotoxicity. We further studied the underlying mechanisms and effects of CTX early post-treatment on behavior in cerebral hypoperfusion rats. The rats' common carotid arteries (2VO) were permanently ligated. was treated after ischemia. Biochemical studies performed to assess antioxidative stress inflammation. Behavioral histological then tested ninth week vessel ligation. 2VO rats showed learning memory deficits as...

Cerebral hypoperfusion is associated with cognitive decline in ageing, mild impairment, vascular type dementia, and Alzheimer's disease.The mechanisms leading to such neurological impairments are still uncertain.Although several have been proposed as contributing factors neuronal injury, glutamate excitotoxicity seems be the relevant one.Recently, it was found that β-lactam antibiotics ceftriaxone show a neuroprotective effect by upregulation of transporter reduction excitotoxicity.To study...

Excessive alcohol consumption is one of the most important causes hepatic steatosis, which involves oxidative stress. In particular, increased stress has been strongly linked to stimulation expression heme oxygenase-1 (HO-1). This study aimed investigate whether HO-1 could alleviates alcoholic steatosis in rats. Male Wistar rats were randomly divided into 4 groups: 1) control group, 2) EtOH 3) + ZnPP-IX group and 4) Hemin group. Liver histopathology was investigated weeks 1 after start...

Abstract Background Paraquat (PQ) has been reported to have a high mortality rate. The major target organ of PQ poisoning is the lungs. pathogenesis PQ-induced lung injury involves oxidative stress and inflammation. Unfortunately, there still no effective antidote for poisoning. We hypothesized that aqueous Thunbergia laurifolia (TL) leaf extract possible injury. Methods total phenolic content caffeic acid an TL leaves were analyzed. Male Wistar rats randomly divided into four groups ( n = 4...

We aim to study the antioxidant ability of Thunbergia laurifolia (TL) aqueous leaf extract against PQ-induced kidney injury. Rats were divided into four groups (n = 4 per group): control group, rats received subcutaneous injection 1 ml/kg body weight (BW) normal saline; PQ 18 mg/kg BW paraquat dichloride; + TL-low dose (LD) dichloride and orally gavaged with TL (100 BW); TL-high (HD) (200 BW). This analyzed blood urea nitrogen (BUN) creatinine levels, renal malondialdehyde (MDA)...

Summary Dried fish exports generate massive revenue. These are in highest demand the world market. However, dried can quickly become spoiled by mould. This creates foul odours that may affect consumer acceptance. requires natural antimicrobial agents to improve shelf life. study aimed control mould growth and organoleptic properties of using Litsea cubeba oil vapour combination with wood smoke. In addition, understand acceptability, treated was used test brain responses...

Abstract In this work, we analyze the epidemic data of cumulative infected cases collected from many countries as reported by WHO starting January 21 st 2020 and up till March 2020. Our inspection is motivated renormalization group (RG) framework. Here propose RG-inspired logistic function form an strength with n being asymmetry in modified function. We perform non-linear least-squares analysis various countries. The uncertainty for model parameters computed using squared root corresponding...

Volume visualization using Direct Rendering (DVR) techniques is used to view information inside 3D volumetric data.Data classified a transfer function emphasize or filter some parts of information, such as that from Computed Tomography (CT) Magnetic Resonance Imaging (MRI).In this paper, we introduced an application for real-time volume rendering interaction with 1D functions Virtual Reality (VR) technology based on the Oculus Rift headset and Touch controllers.Resulting images were...

One of the most popular learning and memory tests is Morris water maze. The maze a circular pool filled with hidden platform under surface. test appropriate for rodents, especially rats mice. testing protocol comprises 2 parts that evaluate ability retention. When animals are placed in pool, they experience stress, which driving force discovery strategy to leave water. In experiment, use environmental cues find location pool. After consecutive training days, can more quickly locate platform....

Purpose: To investigate the antioxidant and anti-inflammatory effects of aqueous leaf extract T. laurifolia against alcoholic liver injury in rats.
 Methods: Male Wistar rats were administered either normal saline, ethanol (EtOH), saline with low or high dose (TL-LD TL-HD), EtOH TL-LD TL-HD. Blood biochemical indices: hepatic malondialdehyde (MDA) levels, histopathology, cytochrome P450 2E1 (CYP2E1), nicotinamide adenine dinucleotide phosphate (NADPH) oxidase, pro-inflammatory...