- Liver Disease and Transplantation
- Neuroscience and Neuropharmacology Research
- Biochemical effects in animals
- Liver Disease Diagnosis and Treatment
- Electrolyte and hormonal disorders
- Hormonal Regulation and Hypertension
- Neuroinflammation and Neurodegeneration Mechanisms
- Diet and metabolism studies
- Stress Responses and Cortisol
- Drug Transport and Resistance Mechanisms
- Neurogenesis and neuroplasticity mechanisms
- Eicosanoids and Hypertension Pharmacology
- Mitochondrial Function and Pathology
- Heavy Metal Exposure and Toxicity
- Alzheimer's disease research and treatments
- Aluminum toxicity and tolerance in plants and animals
- Adipose Tissue and Metabolism
- Neurobiology and Insect Physiology Research
- Trace Elements in Health
- Epilepsy research and treatment
- Axon Guidance and Neuronal Signaling
- Hedgehog Signaling Pathway Studies
- Dye analysis and toxicity
- Dietary Effects on Health
- Regulation of Appetite and Obesity
Université Sultan Moulay Slimane
2023-2024
Cadi Ayyad University
2000-2016
Université Hassan 1er
2012
University of Alberta
2008-2009
Hôpital Saint-Luc
2003-2009
Université de Montréal
2003-2008
Inserm
2003
Hôpital Lariboisière
2003
Hôpital Roger Salengro
2003
Fundación Juan March
2000
Primary papillary tumors of the central nervous system are rare. We have encountered a series six pineal region with distinctive features that appear to represent clinicopathologic entity. The occurred in four women and two men, ranging age from 19 53 years. Imaging studies showed large well-circumscribed mass region. were characterized by an epithelial-like growth pattern, which vessels covered layer tumoral cells. In areas, neoplastic cells large, columnar or cuboidal, clear cytoplasm....
Hepatic encephalopathy (HE) is a neuropsychiatric complication of liver failure. Previous studies described astroglia alterations in HE, but regional changes have not been well investigated. This study addresses astroglial response by exploring glial fibrillary acidic protein (GFAP) immunoreactivity cortical structures including somatosensory (S1Tr and S1BF), piriform (Pir), perirhinal (PRh) cortices, subcortical regions corpus callosum (CC), ventromedial thalamus (VMT), mammillothalamic...
Neurosteroids are cholesterol-derived molecules synthesized within the brain, which exert trophic and protective actions. Infection by human feline immunodeficiency viruses (HIV FIV, respectively) causes neuroinflammation neurodegeneration, leading to neurological deficits. Secretion of neuroinflammatory host viral factors glia infiltrating leukocytes mediates principal neuropathogenic mechanisms during lentivirus infections, although effect neurosteroids on these processes is unknown. We...
Hepatic encephalopathy (HE) is a neuropsychiatric complication of both acute and chronic liver failure characterized by progressive neuronal inhibition. Some neurosteroids are potent positive allosteric modulators the gamma-aminobutyric acid (GABA)-A receptor complex, 'increased GABAergic tone' has been proposed to explain neuroinhibition characteristics HE. Brain levels pregnenolone, allopregnanolone tetrahydrodesoxycorticosterone (THDOC) functional status GABA-A complex were assessed in...
Abstract Fatigue is one of the most common non‐specific symptoms associated with several disease states including liver diseases. Recently, it was reported that levels progesterone metabolites such as allopregnanolone (3α,5α‐tetrahydroprogesterone; 3α,5α‐THP) and isopregnanolone (3β,5α‐THP) were increased in plasma patients chronic fatigue syndrome. We hypothesize THP might be commonly observed evaluated scores five 16 primary biliary cirrhosis (PBC), 12 hepatitis C (CHC) 11 age‐matched...