Saikat Sengupta

ORCID: 0000-0002-1487-5647
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About
Contact & Profiles
Research Areas
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Respiratory Support and Mechanisms
  • Airway Management and Intubation Techniques
  • Neonatal Respiratory Health Research
  • Anesthesia and Sedative Agents
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Hemodynamic Monitoring and Therapy
  • Intensive Care Unit Cognitive Disorders
  • Neuroscience and Neuropharmacology Research
  • Congenital Diaphragmatic Hernia Studies
  • Obstructive Sleep Apnea Research
  • Anesthesia and Neurotoxicity Research
  • Nutrition and Health in Aging
  • Nausea and vomiting management
  • Cardiac Arrest and Resuscitation
  • Neurotransmitter Receptor Influence on Behavior
  • Trauma Management and Diagnosis
  • Frailty in Older Adults
  • Blood transfusion and management
  • Enhanced Recovery After Surgery
  • Pathogenesis and Treatment of Hiccups
  • COVID-19 and healthcare impacts
  • Cardiac Arrhythmias and Treatments
  • Mast cells and histamine

Apollo Gleneagles Hospitals
2006-2022

Apollo Hospitals
2015

Gleneagles Hospital
2006-2013

Vanderbilt University
2010

Medical College and Hospital, Kolkata
2008

Sheppey Community Hospital
1971

Postoperative nausea and vomiting (PONV) are still common following surgery. This is not only distressing to the patient, but increases costs. The thorough understanding of mechanism a careful assessment risk factors provide rationale for appropriate management PONV. Strategy reduce baseline adoption multimodal approach will most likely ensure success in

10.1155/2011/748031 article EN cc-by Anesthesiology Research and Practice 2011-01-01

Activation of 5-hydroxytryptamine2C (5-HT<sub>2C</sub>) receptors by the 5-HT<sub>2</sub> receptor agonist <i>m</i>-chlorophenylpiperazine (<i>m</i>-CPP) elicits anxiety in humans and anxiety-like behavior animals. We compared effects <i>m</i>-CPP with anxiogenic GABA<sub>A</sub> inverse <i>N</i>-methyl-β-carboline-3-carboxamide (FG-7142) on both regional brain activation using functional magnetic resonance imaging (fMRI) rat. also determined whether selective 5-HT<sub>2C</sub> antagonist SB...

10.1124/jpet.106.113357 article EN Journal of Pharmacology and Experimental Therapeutics 2006-11-30

Propofol is one of the widely used intravenous (i.v.) anaesthetics, although pain on injection still remains a considerable concern for anaesthesiologists. A number techniques has been tried to minimize propofol-induced with variable results. Recently, 5-HT(3) antagonist, ondansetron pre-treatment, shown reduce pain. The aim our randomized, placebo-controlled, double-blinded study was determine whether pre-treatment granisetron, which routinely in practice prophylaxis post-operative nausea...

10.4103/0019-5049.96308 article EN cc-by-nc-sa Indian Journal of Anaesthesia 2012-01-01

Summary During 1969 and 1970 toxaemic patients attending the antenatal clinic at Sheppey General Hospital were admitted only if one or more of following criteria satisfied: 1. The urine contained albumin on testing with Albustix. 2. Urinary oestriol excretion was unsatisfactory. 3. obstetric condition duration gestation such that either labour to be induced baby delivered by elective Caesarean section. No case eclampsia seen. A maternal death followed a section for accidental haemorrhage....

10.1111/j.1471-0528.1971.tb00323.x article EN BJOG An International Journal of Obstetrics & Gynaecology 1971-07-01

Complete tracheal resection is extremely rare after blunt chest trauma. A high degree of suspicion essential to identify these cases and early intervention associated with better outcome. We report a patient complete resection, in whom the airway was secured whilst remained awake, breathing spontaneously under fibreoptic bronchoscopic guidance. As precautionary measure, we had kept cardiopulmonary bypass set up readiness. Anaesthetic management needed be modified during repair trachea, by...

10.4103/0971-9784.41582 article EN cc-by-nc-sa Annals of Cardiac Anaesthesia 2008-01-01

Obstructive sleep apnoea (OSA) correlates positively with obesity and age, both of which are becoming increasingly prevalent.Obstructive occurs much more frequently in clinical practice than formerly diagnosed, that this condition represents complex challenges for difÞ culty mask ventilation, laryngoscopic intubation, accelerated arterial desaturation, postoperative monitoring discharge status.In review article pathophysiology, diagnosis, perioperative management group patients have been...

10.4103/0972-5229.43680 article EN Indian Journal of Critical Care Medicine 2008-01-01

i o n s .m e d k w .c m) .Mental impairment following surgery has been a topic status examination (MMSE) and other tests can assess of interest for many years.The acute confusional state speech, consciousness, perception orientation, known as delirium, -is one the most frequently coherence, memory motor activity. [1].The MMSE is encountered complications observed postoperatively.easy to conduct, reliable be used serial The word delirium derived from Latin term meaning testing in fluctuating...

10.4103/0972-5229.29842 article EN Indian Journal of Critical Care Medicine 2006-01-01

Obstructive sleep apnoea syndrome (OSAS) is a common medical disorder among adults, which increasingly being recognized in children too. It breathing characterized by upper airway obstruction with or without intermittent complete that disrupts normal during sleep. Anatomical and neuromuscular disorders are mainly responsible for this disorder. This leads to state of chronic hypoxemia, has significant cardiac, pulmonary central nervous system implications. Diagnosis OSAS based on thorough...

10.4103/0019-5049.60491 article EN cc-by-nc-sa Indian Journal of Anaesthesia 2010-01-01

Systemic mastocytosis is a rare disease due to abnormal proliferation of mast cells (MCs). A case indolent systemic presented here. After anesthetic induction for elective thyroid swelling with propofol and atracurium followed by endotracheal intubation, 57-year-old female patient developed acute hypotension, sinus tachycardia, red rashes, increased airway pressure along difficult ventilation, desaturation. She multiorgan failure subsequently. MC tryptase level was persistently high. Bone...

10.4103/ijccm.ijccm_497_17 article EN Indian Journal of Critical Care Medicine 2018-01-01

GI endoscopy, particularly when performed through the oral route, is considered an aerosol-generating procedure. Such procedures may put endoscopists, anesthetists, and other healthcare personnel at risk.1Peng P.W. Ho P.L. Hota S.S. Outbreak of a new coronavirus: what anaesthetists should know.Br J Anesth. 2020; 124: 497-501Abstract Full Text PDF PubMed Scopus (260) Google Scholar,2Chou R. Dana T. Buckley D.I. et al.Epidemiology risk factors for coronavirus infection in health care workers:...

10.1016/j.vgie.2020.05.018 article EN cc-by-nc-nd VideoGIE 2020-10-01

Appropriate fluid replacement is an essential component of trauma resuscitation.Once hemorrhage controlled, restoration normovolemia a priority.In the presence uncontrolled haemorrhage, aggressive management may be harmful.The crystalloid-colloid debate continues but existing clinical practice more likely to reflect local biases rather than evidence based medicine.Colloids vary substantially in their pharmacology and pharmacokinetics,and experimental finding on one colloid cannot...

10.4103/0972-5229.29843 article EN Indian Journal of Critical Care Medicine 2006-01-01
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