Sujoy Khan
A5088985148- Immunodeficiency and Autoimmune Disorders
- Urticaria and Related Conditions
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Asthma and respiratory diseases
- Drug-Induced Adverse Reactions
- Food Allergy and Anaphylaxis Research
- Blood disorders and treatments
- Allergic Rhinitis and Sensitization
- Chronic Lymphocytic Leukemia Research
- Platelet Disorders and Treatments
- Contact Dermatitis and Allergies
- Mast cells and histamine
- Systemic Lupus Erythematosus Research
- Autoimmune Bullous Skin Diseases
- COVID-19 Clinical Research Studies
- Inhalation and Respiratory Drug Delivery
- Antifungal resistance and susceptibility
- Eosinophilic Disorders and Syndromes
- Blood groups and transfusion
- Hemophilia Treatment and Research
- Appendicitis Diagnosis and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Renal Diseases and Glomerulopathies
- Cystic Fibrosis Research Advances
- Long-Term Effects of COVID-19
Ziauddin University
2025
National Institute of Cardiovascular Diseases
2025
Castle Hill Hospital
2020-2024
Sri Aurobindo Institute of Technology
2024
University of Hull
2010-2024
University Teaching Hospital
2020-2024
Farooq Hospital
2024
National Health Service
2022-2023
Apollo Gleneagles Hospitals
2012-2020
Hull and East Yorkshire Hospitals NHS Trust
2020
Summary Laryngoscopy can induce stress responses that may be harmful in susceptible patients. We directly measured the force applied to base of tongue as a surrogate for response. Force measurements were obtained using three FlexiForce Sensors ® (Tekscan Inc, Boston, MA, USA) attached along concave surface each laryngoscope blade. Twenty‐four 24 adult patients ASA physical status 1–2 studied. After induction anaesthesia and neuromuscular blockade, laryngoscopy tracheal intubation was...
Abstract Background The aim was to describe the management of benign gallbladder disease and identify characteristics associated with all-cause 30-day readmissions complications in a prospective population-based cohort. Methods Data were collected on consecutive patients undergoing cholecystectomy acute UK Irish hospitals between 1 March May 2014. Potential explanatory variables influencing analysed by means multilevel, multivariable logistic regression modelling using two-level hierarchical...
This report summarizes the establishment of first national online registry primary immune deficency in United Kingdom, Kingdom Primary Immunodeficiency (UKPID Registry). UKPID Registry is based on European Society for Immune Deficiency (ESID) platform, hosted servers at Royal Free site University College, London. It accessible to users through website Network (www.ukpin.org.uk). Twenty-seven centres are actively contributing data, with an additional nine completing their ethical and...
Summary Hereditary angioedema (HAE) and acquired (AAE) are rare life-threatening conditions caused by deficiency of C1 inhibitor (C1INH). Both characterized recurrent unpredictable episodes mucosal swelling involving three main areas: the skin, gastrointestinal tract larynx. Swelling in results abdominal pain vomiting, while larynx may be fatal. There limited UK data on these patients to help improve practice understand more clearly burden disease. An audit tool was designed, informed...
Uncomplicated acute appendicitis can be managed with non-operative (antibiotic) treatment, but laparoscopic appendicectomy remains the first-line management in UK. During COVID-19 pandemic practice altered, more patients offered antibiotics as treatment. A large-scale observational study was designed comparing operative and of appendicitis. The aim this to evaluate 90-day follow-up.
Abstract In March 2020, the United Kingdom Primary Immunodeficiency Network (UKPIN) established a registry of cases to collate outcomes individuals with PID and SID following SARS-CoV-2 infection treatment. A total 310 in or have now been reported UK. The overall mortality within cohort was 17.7% (n = 55/310). Individuals CVID demonstrated an fatality rate (IFR) 18.3% 17/93), receiving IgRT had IFR 16.3% 26/159) SID, 27.2% 25/92). higher inpatient died at younger age than general population....
The aims of this prospective population-based cohort study were to identify the patient and hospital characteristics associated with emergency cholecystectomy, influences these in determining variations between hospitals.Data collected for consecutive patients undergoing cholecystectomy acute UK Irish hospitals 1 March May 2014. Potential explanatory variables influencing performance analysed by means multilevel, multivariable logistic regression modelling using a two-level hierarchical...
Individuals with primary and secondary immunodeficiency (PID/SID) were shown to be at risk of poor outcomes during the early stages SARS-CoV-2 pandemic. vaccines demonstrate reduced immunogenicity in these patients.
Abstract Abdominal pain is a frequent presentation encountered by the primary care physician. Acute appendicitis accounts for small but significant proportion of abdominal cases seen. Among known etiologies mimicking appendicitis, foreign-body ingestion exceedingly rare and may be easily misdiagnosed as another cause acute abdomen lead to need emergency surgery. It might challenging establish diagnosis if patient cannot recollect having swallowed foreign body. We report an interesting case...
Objective: to determine frequency of depression and anxiety after primary percutaneous coronary intervention among patients with acute mayocardial infarction using Hamilton rating scale. Methods: This cross-sectional study was performed in outpatients’ clinics interventional cardiology National Institute Cardiovascular Diseases, Karachi, Pakistan from 1st January 2024 30th July 2024. The enrolled underwent within our hospital premises. Anxiety were evaluated based on Rating Scale for will be...
Objectives Accurately predicting short-term MACE (major adverse cardiac events) following primary percutaneous coronary intervention (PCI) remains a clinical challenge. This study aims to assess the effectiveness of four established risk scores in after PCI. Design Prospective observational study. Setting The National Institute Cardiovascular Diseases, Karachi, Pakistan. Participants We enrolled cohort consecutive adult patients diagnosed with ST-elevation myocardial infarction undergoing...
There is limited literature on the psychological distress among unmarried women in Pakistan, where reason behind being a concerning issue due to country's collectivistic society, which highly regards and respects marriage, unlike living relationships that are both legally culturally prohibited. The objective of this study highlight rising cultural Pakistan by investigating distress, operationalized as anxiety depression, through cross-sectional correlational design purposive sampling...
Abstract Background The optimal timing of cholecystectomy for patients admitted with acute gallbladder pathology is unclear. Some studies have shown that emergency during the index admission can reduce length hospital stay similar rates conversion to open surgery, complications and mortality compared a ‘delayed’ operation following discharge. Others reported results in higher morbidity, extended increased costs. This study examined cost-effectiveness versus delayed benign disease. Methods...
Background Median diagnostic delay of five to six years seen in primary hypogammaglobulinaemia results morbidity including bronchiectasis. Patients typically have multiple health care encounters and blood tests before the diagnosis is considered. We report outcomes from using difference between total protein albumin (globulin fraction) reduce unsuspected hypogammaglobulinaemia. Methods A prospective >5 year programme setting a National Health Services Hospital Blood Sciences pathology...
Background: The appropriate testing strategy for diagnosing pernicious anaemia using gastric parietal cell (GPC) and/or intrinsic factor antibodies (IFA) is controversial. Intrinsic are found in only about 70% of cases. Indirect immunofluorescence screening more sensitive, labour intensive, and less specific. Methods: frequency antibody positivity (IFA GPC) was retrospectively examined patients tested both autoantibodies over a three-year period. It investigated whether B12 levels were...
Therapeutic regimens of intravenous immunoglobulin are currently based on actual body weight. The relationship between dose and serum IgG level in relation to size was retrospectively explored patients replacement therapy. Data were collected as part a national audit therapy with common variable immunodeficiency. 107 received titrated optimum effect. Correlations sought mass index, trough levels, infusion frequency total annual dose. mean (±SD) 8.4±1.6 g/L 456.8±129.4 g. There no level,...
Chronic idiopathic urticaria is a common skin disorder characterized by recurrent appearance of wheals and/or angioedema for more than 6 weeks without an identifiable cause. Consensus guidelines suggest use leukotriene receptor antagonists (montelukast or zafirlukast) in patients whose resistant to antihistamines. Our objectives were (1) document the efficacy montelukast our patients, and (2) evaluate whether any clinical features available laboratory investigations associated with response...