- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Structural Anomalies and Repair
- Cardiac pacing and defibrillation studies
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Artery Anomalies
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Arrest and Resuscitation
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Cardiac Arrhythmias and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Aortic Disease and Treatment Approaches
- Hernia repair and management
- Emergency and Acute Care Studies
- Vascular anomalies and interventions
- Streptococcal Infections and Treatments
- Cardiovascular Disease and Adiposity
National Institute of Cardiovascular Diseases
2012-2025
Ziauddin University
2020
Aga Khan Hospital for Women
2020
Shaikh Khalifa Medical City
2018
Objectives Accurately predicting short-term MACE (major adverse cardiac events) following primary percutaneous coronary intervention (PCI) remains a clinical challenge. This study aims to assess the effectiveness of four established risk scores in after PCI. Design Prospective observational study. Setting The National Institute Cardiovascular Diseases, Karachi, Pakistan. Participants We enrolled cohort consecutive adult patients diagnosed with ST-elevation myocardial infarction undergoing...
Objectives: Patients with ST elevation myocardial infarction (STEMI) presenting high Killip class face an elevated risk of adverse outcomes. This study aimed to evaluate the in-hospital outcomes and identify predictors mortality in such patients admitted intensive care unit (ICU) after primary percutaneous coronary intervention (PCI) at a tertiary cardiac center low-middle income country. Methodology: A descriptive cross-sectional was conducted ICU Pakistan. The included adult (≥18 years)...
Primary percutaneous coronary intervention (PCI) remains recommended reperfusion therapy for patients with acute ST-elevation myocardial infarction. This study aimed to evaluate the short-term major adverse cardiac events (MACE) and their determinants among who underwent primary PCI at a tertiary care center of Karachi, Pakistan.A cohort were followed MACE. Multivariable Cox-regression analysis was performed backward conditional variable selection hazard ratio (HR) along 95% confidence...
To know the predictors of a successful outcome percutaneous transvenous mitral commissurotomy (PTMC) other than described in Wilkins scoring system.Two hundred fifty-eight consecutive patients were enrolled for this observational study tertiary care heart center Pakistan who had score ≤ 8. Patients with more mild regurgitation (MR) or having clot left atrium excluded. The Bonhoeffer multi-track system was used as default technique. Successful PTMC defined achieving valve area (MVA) ≥ 1.5...
Abstract Background The aim of this study was to determine the predictive value Global Registry Acute Coronary Events (GRACE) score for predicting in-hospital and 6 months mortality after non-ST elevation acute coronary syndrome (NSTE-ACS). Results In observational study, 300 patients with NSTE-ACS age more than 30 years were included; 16 died during hospital stay (5.3%). Of 284 at assessment, 10 (3.5%), 240 survived (84.5%), 34 lost follow-up (12%) respectively. high risk category, 10.5%...
Background In the current coronavirus disease-2019 (COVID-19) pandemic, pattern of hospital admissions for acute ST-elevation myocardial infarction (STEMI) is changing, and increased mortality morbidity being noted in these patients. Cardiac manifestations COVID-19 are complex include STEMI, myocarditis, injury, cardiomyopathy. The objective our study was to compare data patients with STEMI presenting versus non-COVID-19 era. Methods We analyzed clinical angiographic characteristics...
Background: Improvement in left ventricular (LV) function after revascularization is an important determinant of long-term prognosis a patient with acute myocardial infarction (AMI). However, data on the changes LV are scarce our population. Hence, this study was conducted to evaluate and dimensions by echocardiography at 3 6 months primary percutaneous coronary intervention (PCI). Materials Methods: A total 188 patients were recruited who had undergone PCI. Patients preexistent dysfunction,...
The thrombosis of the stent is one most important complications percutaneous interventions, resulting in complete occlusion stented vessel. Aim this study was to determine validity Stent Thrombosis Risk Score (STRS) predicting early (ST) after primary Percutaneous Coronary Intervention (PCI).For study, 569 consecutive patients undergone PCI from July 2018 December were recruited. Early ST defined as occurred during or within 30 days procedure. STRS calculated proposed, developed, and...
Background The aim of this study was to evaluate the safety and efficacy transcatheter aortic valve implantation (TAVI) program in a Tertiary care hospital Karachi, Pakistan. Methodology This conducted by interventional cardiology department National Institute Cardiovascular Diseases (NICVD), Karachi from July 2015 February 2020. All patients severe stenosis (AS) who underwent TAVI were included. Baseline characteristics, in-hospital course one-month follow-up data collected. Results...
<title>Abstract</title> BACKGROUNDː Transposition of the Great Arteries (TGA) is one most common types congenital heart defects (CHD). Recent advances in computed tomography angiography (CTA) have helped detection this condition. However, scientific literature remains scarce with regards to a comparison between Iran and Pakistan, hence study was conducted. METHODSː A cross-sectional conducted comparing patient cohorts from Pakistan Iran. Patients diagnosed CHD as confirmed by CTA, aged less...
Background ST elevation myocardial infarction (STEMI) is classically characterized by total occlusion of the culprit coronary artery. However during primary percutaneous intervention (PCI) thrombolysis in (TIMI) 0 flow not observed all patients' arteries angiographic views. This study was conducted to find out frequency TIMI acute STEMI patients view above concept. The aim this evaluate pre-procedural III those who underwent PCI for a public sector hospital Karachi, Pakistan. Methodology an...
: Global ST depression in 8 or more leads along with elevation aVR has been considered as hallmark of widespread sub-endocardial ischemia. It associated left main (LM) stem three vessel disease (3VD). But different studies have shown results. We collected data from patients to see association these ECG changes significant LM and/or (3VD).TIt was a prospective observational study performed at tertiary care cardiac center. All acute coronary syndrome (ACS) having global and Elevation (that is...
Objectives: To assess the knowledge about valvular heart disease among patients who are already diagnosed with rheumatic (RVHD). Methodology: In this cross-sectional study was conducted at outpatient of a tertiary care cardiac centre. We included consecutive either gender between 18 to 60 years age established diagnosis RVHD. Their and awareness regarding itself its primary secondary prevention treatment options assessed help structured self-developed questionnaire. Results: Among sample 505...
Objectives: Acute kidney injury (AKI) is frequently present co-morbid condition in patients admitted with acute heart failure (AHF). This study aimed to determine the frequency of in-hospital mortality AHF presenting AKI. Methodology: descriptive case series AKI was conducted at a tertiary care cardiac hospital Karachi, Pakistan. In accordance “Risk, Injury, Failure, Loss, and End‐Stage Renal Disease (RIFLE) scale," defined as 3.0‐fold increase serum creatinine (sCr) or sCr > 4.0 mg/dL...
Primary percutaneous coronary intervention (PCI) is a recommended management strategy for patients with de novo ST-segment elevation myocardial infarction (STEMI). Still, the efficacy of primary PCI in-stent thrombosis (ST) induced STEMI unclear. The aim was to assess clinical characteristics and in-hospital outcomes undergoing caused by acute, sub-acute, or late ST. A sample hundred consecutive who presented due ST were included in this study. angiographic evidence flow-limiting thrombus...