Abstract Background The aim of our research was to design and evaluate an Artificial Neural Network (ANN) model using a systemic grid search for the early prediction major adverse cardiac events (MACE) among patients presenting triage emergency department. Methods This is single-center, cross-sectional study electronic health records from January 2017 December 2020. population consists adults coming department at Aga Khan University Hospital. MACE during hospitalization main outcome. To...

Tuberculosis remains a major cause of morbidity in endemic areas. Isoniazid (INH) is an important first-line agent for its treatment. Its adverse effects include hepatotoxicity and neurotoxicity. Neurological side usually occur at toxic doses; however, few cases have reported generalized seizures therapeutic doses. Focal after doses are rare. Here, we present the case 78-year-old male diagnosed with squamous cell carcinoma lung pulmonary tuberculosis who experienced focal INH administration....

Abstract Abdominal pain is a frequent presentation encountered by the primary care physician. Acute appendicitis accounts for small but significant proportion of abdominal cases seen. Among known etiologies mimicking appendicitis, foreign-body ingestion exceedingly rare and may be easily misdiagnosed as another cause acute abdomen lead to need emergency surgery. It might challenging establish diagnosis if patient cannot recollect having swallowed foreign body. We report an interesting case...

Abstract Background The incidence of heat emergencies, including stroke and exhaustion, have increased recently due to climate change. This has affected global health become an issue consideration for human well-being. Due overlapping clinical manifestations with other diseases, most these emergencies occurring in elderly patient, patients a comorbid condition, or on poly medicine, diagnosing managing them the emergency department can be challenging. study assessed whether educational...

We aimed to determine a comparison between the Quick Sequential Organ Failure Assessment (qSOFA) score and existing (SOFA) when applied severe sepsis & septic shock patients in Emergency Department (ED) for prediction of in-hospital mortality setting tertiary care hospital ED low-middle income country.We conducted prospective observational cohort study on 760 subjects. The qSOFA, SOFA were assessed by area under receiver operating curve (AUROC). calculated sensitivity specificity each...

This study aimed to estimate the burden of unintentional poisoning in South Asian countries from 1999 2019.An ecological conducted at regional level for countries, based on data Global Burden Disease Study 2019.We extracted set 1990 2019 assess trends mortality, disability-adjusted life-years (DALYs), years life lost, lived with disability (YLDs) and causative agents (Bangladesh, Bhutan, India, Nepal Pakistan).We determined per cent change 95% CI period between by age, gender country. We...

Emergency physicians (EPs) working in low-resource settings, where patients mainly bear the cost of healthcare delivery, face many challenges. care is patient-centered and ethical challenges are numerous situations patient autonomy beneficence fragile. This review discusses some common bioethical issues resuscitation postresuscitation phases treatment. Solutions proposed necessity for evidence-based ethics unanimity on standards emphasized. After a consensus was reached structure article,...

Abstract Background Prediction of serious outcomes among patients with physiological instability is crucial in airway management. In this study, we aim to develop a score predict following intubation critically ill adults by using clinical and laboratory parameters collected prior intubation. Method This single-center analytical cross-sectional study was conducted the Emergency Department from 2016 2020. The derived transparent reporting multivariable prediction model for individual...

New onset refractory status epilepticus (NORSE) is a new entity in medical literature. It has different infectious and noninfectious etiologies showing devastating impact onto the clinical outcome of patients. Therapy with anaesthetic antiepileptic agents often fails to improve condition, unless primary cause rectified. Here presented case young female history depression who after recent bereavement came Emergency Department Aga Khan University Hospital complaints drowsiness that lasted for...

A case of a 30-year-old woman with an end-stage renal disease and recently diagnosed infective endocarditis, who presented acute abdominal pain. An initial assessment appendicitis was made. CT scan the abdomen showed partially occluded superior mesenteric artery radiographic evidence ischaemia in ileal loop. Intraoperatively, 5–6 cm segment distal ileum found to be non-viable. The resected creation double-barrel ileostomy. This report draws attention question need for anticoagulation septic...

Abstract Background Critically-ill Covid-19 patients require extensive resources which can overburden a healthcare system already under strain due to pandemic. A good disease severity prediction score help allocate where they are needed most. Objectives We developed Severity Assessment Score (CoSAS) predict those likely suffer from mortalities within 28 days of hospital admission. also compared this Quick Sequential Organ Failure (qSOFA) in adults. Methods CoSAS includes the following 10...

Heat stroke is a deadly condition that needs astute care and timely management. Recently, the city of Karachi in Pakistan has been victim an intense heat wave, which resulted insurmountable loss life. We observed various deficiencies dealing with this national threat provides us valuable lesson regarding measures can be undertaken to avoid such disaster from occurring again. (Eurasian J Emerg Med 2015; 14: 209-10)

Electroencephalogram and neuroimaging in pediatric patients with new-onset afebrile seizures are performed to detect any underlying pathological severe condition that may require emergent neuro-intervention guide prognosis. This study aims determine the predictors of abnormal EEG children presenting emergency department seizures.This single-center cross-sectional was conducted at a tertiary care hospital Karachi, Pakistan, from July 01, 2019, June 30, 2021. All aged one month 18 years who...

Abstract Acute pancreatitis (AP) refers to the acute inflammation of pancreas; however, if there is concurrent necrosis, it called necrotizing (NAP). The diagnosis sometimes difficult because might mimic coronary syndrome (ACS). We report a case 28-year-old male, who presented emergency department (ED) with severe epigastric pain, shortness breath and diaphoresis for 4–5 h. initial electrocardiogram (ECG) showed marked sinus bradycardia an incomplete left bundle branch block. Considering...

BACKGROUND: Pakistan has been hugely struck with massive bomb explosions (car and suicide bombs) resulting in multiple casualties the past few years.The aim of this study is to present patterns skeletal soft tissue injuries review outcome victims who presented our hospital.METHODS: This a retrospective chart from January 2008 December 2012.The medical record numbers patients were obtained hospital Health Information Management Sciences (HIMS) as per ICD-9 coding.RESULTS: During period, more...

Abstract Urogenital emergencies demand immediate attention within the field of emergency medicine, encompassing a range critical conditions from ectopic pregnancies to kidney stones. Timely diagnosis and treatment are vital prevent potential mortality morbidity. However, due sensitive nature these disorders cultural taboos surrounding them, accessing prompt medical care can be challenging. To bridge this gap, innovative gamification-based learning techniques, such as Learning Diseases in...

Background. Critically ill patients have increased risk of cardiovascular collapse following endotracheal intubation due to physiological instability. This study aims validate the Difficult Airway Physiological Score (DAPS) in adults predict serious outcomes emergency department a tertiary care private hospital. Methods. is cohort conducted (ED) from 2021 2022. was derived sample 1021 through retrospective study. The variables score were age, gender, time intubation, vitals and vomiting at...

Terminal ballistics continues to struggle with bullet trajectory reconstruction and interpretation. This is a case of young man presented very unusual from the left shoulder brain parenchyma. The single wound altered mentation prompted CT head neck scan, which revealed retained in parenchyma, traversing shoulder, across into without causing significant damage vital organs. We managed patient conservatively. Emergency physicians dealing gunshot injuries should thoroughly search for cases...

Gender variation in critically ill adults after resuscitation is reported many studies. However, this not well established when evaluating the physiological instability population. This study aimed to prospectively evaluate gender serious outcomes by difficult airway score (DAPS) among patients requiring endotracheal intubation (ETI). a cohort conducted from August 2021 December 2022 emergency department of Aga Khan University. The prospective validity was derived using retrospective data...

The burden of time-sensitive illnesses that require emergency care, such as heart diseases, respiratory tract infections, and road traffic injuries, is the leading cause premature deaths. healthcare providers care system lack essential knowledge skills across different levels in our country. In this paper, we aim to describe development initial implementation a blended learning curriculum for teaching training non-EM-trained physicians working departments We used previously articulated...