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Research Areas
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- RNA regulation and disease
Dalian Medical University
2022
Second Affiliated Hospital of Dalian Medical University
2022
Parkinson's disease (PD) is a leading cause of disability. Long noncoding RNA (LncRNA) OIP5-AS1 alleviates the accumulation and toxicity 1-methyl-4-phenylpyridine (MPP+ )/-induced α-synuclein in human neuroblastoma SH-SY5Y cells, which may be involved pathological process PD. This study explored neuroprotective effect lncRNA on MPP+ /-induced cell model PD, so as to provide theoretical basis for PD treatment. The was established group). overexpression vector oe-OIP5-AS1 constructed...
10.1002/kjm2.12485
article
EN
cc-by-nc-nd
The Kaohsiung Journal of Medical Sciences
2022-01-20
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