Aldo Milzani

ORCID: 0000-0002-1496-6872
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About
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Research Areas
  • Redox biology and oxidative stress
  • Sulfur Compounds in Biology
  • Cellular Mechanics and Interactions
  • Nitric Oxide and Endothelin Effects
  • Glutathione Transferases and Polymorphisms
  • Advanced Glycation End Products research
  • Biochemical effects in animals
  • Folate and B Vitamins Research
  • Dialysis and Renal Disease Management
  • Alcohol Consumption and Health Effects
  • Antioxidant Activity and Oxidative Stress
  • Cardiomyopathy and Myosin Studies
  • Marine Biology and Environmental Chemistry
  • Genomics, phytochemicals, and oxidative stress
  • Mast cells and histamine
  • Protein Interaction Studies and Fluorescence Analysis
  • Hemoglobin structure and function
  • Electron Spin Resonance Studies
  • Force Microscopy Techniques and Applications
  • Polymer Surface Interaction Studies
  • Muscle metabolism and nutrition
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Vitamin C and Antioxidants Research
  • Eicosanoids and Hypertension Pharmacology
  • Chronic Kidney Disease and Diabetes

University of Milan
2015-2024

University of Insubria
2009

Nagoya University
2007

Patients with end‐stage renal disease (ESRD) undergoing haemodialysis (HD) experience oxidative/carbonyl stress, which is postulated to increase after the HD session. The influence of diabetes mellitus and sex on oxidation plasma proteins in ESRD has not yet been clarified despite that diabetic nephropathy most common cause developed developing countries increasingly emerging differences between males females epidemiology, pathophysiology, clinical manifestations, outcomes for several...

10.1155/2018/4149681 article EN cc-by Oxidative Medicine and Cellular Longevity 2018-01-01

Abstract Background: The reported mean concentration of glutathione disulfide (GSSG) in human blood/erythrocytes varies widely (1 to >500 μmol/L), as does that reduced (GSH) a lesser extent. We have identified and investigated possible pitfalls measurement both GSH GSSG. Methods: measured GSSG using spectrophotometer with modification the recycling method; same samples were also by reversed-phase HPLC after derivatization thiols (dithiothreitol was used reduce disulfides)...

10.1093/clinchem/48.5.742 article EN Clinical Chemistry 2002-05-01

Reduced glutathione (GSH) and its redox forms, disulfide (GSSG) glutathionylated proteins (PSSG), are biomarkers of oxidative stress, but methodologic artifacts can interfere with their measurement. We evaluated the importance correct sample handling during preanalytical phase for GSH, GSSG, PSSG measurement.We used human blood in vitro experiments oxidants [tert-butylhydroperoxide (t-BOOH), diamide, menadione]. For vivo experiments, we rats which cannulated jugular femoral veins both...

10.1373/clinchem.2006.067793 article EN Clinical Chemistry 2006-05-12
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