Görkem Dülger

ORCID: 0000-0002-1506-1549
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Phytochemistry and Biological Activities
  • Bee Products Chemical Analysis
  • Phytochemicals and Antioxidant Activities
  • Plant Pathogens and Fungal Diseases
  • Metal complexes synthesis and properties
  • Natural product bioactivities and synthesis
  • Synthesis and biological activity
  • Microbial Natural Products and Biosynthesis
  • Insect and Pesticide Research
  • Phytochemistry and Bioactivity Studies
  • Medicinal Plant Research
  • Asymmetric Hydrogenation and Catalysis
  • Nanoparticles: synthesis and applications
  • Natural Compound Pharmacology Studies
  • Multicomponent Synthesis of Heterocycles
  • Tannin, Tannase and Anticancer Activities
  • Ethnobotanical and Medicinal Plants Studies
  • Fungal Biology and Applications
  • Bioactive Compounds and Antitumor Agents
  • Ginger and Zingiberaceae research
  • biodegradable polymer synthesis and properties
  • Bryophyte Studies and Records
  • Ultrasound and Cavitation Phenomena
  • Chemical synthesis and alkaloids

Düzce Üniversitesi
2014-2024

Bezmiâlem Vakıf Üniversitesi
2023

University of Benin
2009

Çanakkale Onsekiz Mart Üniversitesi
2009

Methoxy group enriched eight coumarin-chalcone hybrid derivatives were synthesized. Antimicrobial/ antiproliferative activities tested against human pathogenic microorganisms and four cancer cell lines (AGS, HepG2, MCF-7 PC-3), respectively. Antimicrobial results showed that most of the compounds almost more active than used standard antibiotics. Cytotoxicity 2,3,4-trimethoxyphenyl thiophene containing structures have promising effects AGS gastric with ∼5 μg/ml IC50 values. At same time,...

10.1002/cbdv.202200973 article EN Chemistry & Biodiversity 2023-01-24

The association between dysbiotic microbiota biofilm and colon cancer has recently begun to attract attention. In the study, apitherapeutic effects of bee products (honey, venom, royal jelly, pollen, perga propolis) obtained from endemic Yığılca ecotype Apis mellifera anatoliaca were investigated. Antibiofilm activity performed by microplate assay using crystal violet staining measure adherent biomass Escherichia coli capable forming biofilms. Bee venom showed highest inhibition effect...

10.1080/08927014.2024.2338106 article EN Biofouling 2024-04-07

Purpose: The ethanol extract of the leaves Stachys pseudopinardii R. Bhattacharjee and Hub.–Mor. (Lamiaceae) were investigated for their antimicrobial activities.Methods: activity leaf plant was tested against Bacillus subtilis ATCC 6633, cereus 7064, Staphylococcus aureus 6538P, Escherichia coli 10538, Proteus vulgaris 6899, Salmonella typhimurium CCM 5445 Pseudomonas aeruginosa 27853, as well Candida albicans 10239, Debaryomyces hansenii DSM 70238, Kluyveromyces fragilis 8608 Rhodotorula...

10.4314/tjpr.v8i4.45231 article EN cc-by Tropical Journal of Pharmaceutical Research 2009-08-20

Purpose: To investigate the antifungal activities.of individual as well combined hydroalcohol leaf and root extracts of endemic Hypericum havvae A. Guner (Hyperiaceae).Methods: Each dry powdered plant material (20 g) was soaked in 150 ml aqueous ethanol (50: 50 %v/v) until complete saturation material. After were filtered evaporated, activity tested against medical yeast, Candida (C. albicans ATCC 10231, C. tropicalis 13808, guilliermondii 6260) Cryptococcus neoformans 90112 laurentii 34142)...

10.4314/tjpr.v13i3.14 article EN cc-by Tropical Journal of Pharmaceutical Research 2014-05-27

In this study, the antimicrobial, antioxidant and antitumor activity of ethanol extracts obtained from Phlomis russeliana (Sims.) Lag. ex Benth. (Lamiaceae) were evaluated. Disc diffusion microdilution methods used to test for antimicrobial against seven bacteria strains (Bacillus cereusATCC 7064, Bacillus subtilisATCC 6633, Staphylococcus aureusATCC 6538P, Escherichia coliATCC 10538, Proteus vulgarisATCC 6899, Salmonella typhimuriumCCM 5445 Pseudomonas aeruginosaATCC 27853) four yeast...

10.1590/0001-3765201920180404 article EN cc-by Anais da Academia Brasileira de Ciências 2019-01-01

Bacteria act through a communication mechanism called quorum sensing (QS) to control pathogenicity. Biofilm formation is process supported by the QS and known part in antibiotic resistance. In this study, antimicrobial, anti-QS antibiofilm capacities of ethanol extracts obtained from Lamium galeobdolon (L.) L. purpureum plants were determined. The antimicrobial activity plant was evaluated well diffusion assay against various hospital isolates. have effects all bacteria yeasts. 27.5 ± 0.71...

10.35206/jan.1457624 article EN Journal of Apitherapy and Nature 2024-06-30

Nanoteknolojinin ilginç yönlerini keşfetmek adına son yıllarda birbirinden farklı birçok çalışma yapılmaktadır. Nanomalzeme üretiminin hızlı gelişimi, çok çeşitli alanlarda metal oksit (ZnO) uygulamalarını da beraberinde getirmiştir. Çinko nanopartikülleri (ZnO NP), ticari kullanım için mekanik veya kimyasal olarak elde edilebilir. Ancak, bu tekniklerin ortaya çıkardığı çevre sorunları bir hayli dikkat çekmiştir. Günümüzde, ZnO NP’nin yeşil sentezi, sorunlarını azaltmayı amaçlayan araştırma...

10.29130/dubited.1082788 article TR cc-by-nc Düzce Üniversitesi Bilim ve Teknoloji Dergisi 2023-04-27

Abstract Thio-Schiff bases are becoming increasingly widespread in various branches such as the preparation of certain medicines, cosmetic products, and polymer production. In particular, presence antibacterial, antifungal, antiviral, antitumor antimalarial properties Schiff containing sulfur structure has made these compounds attractive different disciplines. this study, derivatives dimeric disulfide-Schiff have been synthesized. The antibacterial antifungal activities synthesized were...

10.24190/issn2564-615x/2017/03.06 article EN cc-by-nc-nd The EuroBiotech Journal 2017-07-20

Nanopartiküllerin sentezi, yeni teknolojilerin geliştirilmesiyle birlikte ilgili potansiyel uygulamalar için bir araştırma alanıdır; özellikle, çevre dostu nanomalzemeler, nanobilim içinde büyüyen alan haline gelmiştir. Son zamanlarda, bitki özleri ve arı ürünleri kullanılarak metal oksit nanopartiküllerin nanobiyoteknoloji alanında, geleneksel fizikokimyasal yaklaşımlara göre sayısız avantajlarla ilgi çekici konu olarak ortaya çıkmıştır. Bu çalışmada, çinko (ZnO NP’in) sentezi için, kestane...

10.29130/dubited.1100628 article TR cc-by-nc Düzce Üniversitesi Bilim ve Teknoloji Dergisi 2023-07-24

The current study aimed to evaluate Lamium purpureum L. in terms of its chemical composition and the potential essential oil for anticancer activity. profiling analysis was carried out via GC-MS. For this purpose, ethanol extract subjected GC-MS determine compounds. To obtain oil, steam distillation whole plant (aerial, leaf, stem) a Clevenger apparatus. activitiy determined MTT assay. We observed that maximum cell death 14% at 50 μg/mL concentration. As result analysis, palmitic acid,...

10.29130/dubited.553793 article EN cc-by-nc Düzce Üniversitesi Bilim ve Teknoloji Dergisi 2019-07-31

Benzothiazole compounds are known as an important bicyclic ring system with multiple applications. These have a wide range of biological activities, including anticancer, antimicrobial, anti-inflammatory and antiviral activities. In this study, benzothiazole were synthesized their various activities examined. The benzothiazoles evaluated for antimicrobial properties against bacterial fungal strains. compound 6e is most active ligand in the series bacteria fungi compared to standard...

10.1590/0001-3765202420230423 article EN cc-by Anais da Academia Brasileira de Ciências 2024-01-01

ÖZSon on yılda Corynebacteria kaynaklı farklı klinik enfeksiyonların sayısında artış bildirilmiştir.Bu çalışma, kültürde üreme şekline göre (saf, başka bir patojen bakteriyle birlikte ve polimikrobiyal üreme) üç gruba ayrılan korinebakterilerin antibiyotik direnç oranları ile biyofilm oluşturma kapasitelerini değerlendirmek ''anti-quorum-sensing [çoğunluk algısı (QS)]" aktivitelerini araştırmak amacıyla planlanmıştır.Düzce Üniversitesi Tıp Fakültesi Hastanesi Başakşehir Çam Sakura Şehir...

10.5578/mb.20249704 article TR Mikrobiyoloji Bulteni 2024-07-19

In this study, the ethanolic crude extracts obtained from macrofungus Suillus collinitus (Fr.) O. Kuntze (Suillaceae, Bolatales) were investigated for their antifungal activities against dermatophytes such as isolates Microsporum gypseum, Trichophyton rubrum and Epidermophyton floccosum by agar well diffusion method tube dilution method. The ethanol have a strong effect with mean values zone of inhibition at different concentrations wide was determined 1500 mg/mL (20.8 mm) M. (18.2 T. (16.8...

10.30616/ajb.1538739 article EN Anatolian Journal of Botany 2024-12-11

The purpose of this study was to investigate the antimicrobial activity formulations F. fomentarius . efficacy levels extracts prepared from ethanol, water and various (emulsion, ointment, paste, cream gel) were determined. For purpose, disk diffusion method used test for against hospital isolates including Klebsiella pneumoniae, Acinetobacter baumannii, Staphylococcus aureus , vancomycin-resistant enterococci (VRE+), Escherichia coli, Candida krusei, C. albicans, tropicalis, guilliermondii...

10.30708/mantar.535994 article EN Mantar Dergisi 2019-10-30

Aqueous and ethanolic extracts obtained from two brown algae ( Cystoseira compressa (Esper) Gerloff et. Nizamuddin) Padina pavonica (Linnaeus) Thivy) have been investigated for their ability to inhibit 35 hospital isolates of methicillin-resistant Staphylococcus aureus (MRSA). Both aqueous the plant were effective on MRSA. The minimum inhibitory concentration (MIC) bactericidal (MBC) values extract with greatest antibacterial activity those MIC 3.2-6.3mg/mL MBC 6.3-25mg/mL, respectively.

10.9734/bmrj/2014/10449 article EN British Microbiology Research Journal 2014-01-10
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