Hongyao Lin

ORCID: 0000-0002-1524-9699
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About
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Research Areas
  • Viral gastroenteritis research and epidemiology
  • Animal Virus Infections Studies
  • Virus-based gene therapy research
  • Animal Behavior and Welfare Studies
  • Reproductive Physiology in Livestock
  • Microbial infections and disease research
  • Animal Disease Management and Epidemiology
  • SARS-CoV-2 and COVID-19 Research
  • Effects of Environmental Stressors on Livestock
  • Genetic and phenotypic traits in livestock

Background/Objectives: Porcine reproductive and respiratory syndrome virus (PRRSV) has a major impact on swine productivity. Modified-live vaccines (MLVs) are used to aid in control. We investigated the cross-protection provided by lineage 7 PRRSV MLV against 1 isolate under laboratory conditions 3 challenge field Taiwan. Methods: In first study, thirty PRRS antibody-negative conventional piglets were vaccinated via intramuscular (IM) or intradermal (ID) route, with control group receiving...

10.3390/vaccines13020102 article EN cc-by Vaccines 2025-01-21

Porcine epidemic diarrhea (PED) is caused by the PED virus, with genogroup 2 (G2), comprising G2a and G2b, being primary contributors to outbreaks worldwide. In Thailand, was only virulent strain identified until emergence of first G2b in 2014, followed additional strains 2015–2016, particularly those closely related from China. This led increased awareness more frequent complex outbreaks. study examined farms affected strains, both employing planned exposure sows intestines G2a-affected...

10.3390/ani15020225 article EN cc-by Animals 2025-01-15

Porcine epidemic diarrhea virus (PEDV) is an economically important pathogen of swine, causing severe in neonates with high morbidity and mortality. Vaccination a key strategy for PEDV control, but optimizing regimens based on herd status essential improving immunity protection. This study evaluated immune responses to different vaccination protocols using PED replicon vaccine (PED-RP) Thai swine farms varying statuses. Two field trials were conducted: Experiment 1 (n = 120) PED-negative...

10.3390/ani15020273 article EN cc-by Animals 2025-01-19

This study was conducted to evaluate the protective efficacy of modified live vaccines (MLVs) against porcine reproductive and respiratory syndrome (PRRS) in nursery pigs a worst case scenario where MLV does not match genetic profile field isolate, different MLVs are used for sows piglets, piglets naturally exposed genetically distinct heterologous PRRS virus (PRRSV) isolates. We divided 76,075, 2-week-old from seropositive sow herd vaccinated with US1-MLV into four groups. US1-MLV, US2-MLV,...

10.3390/ani15030428 article EN cc-by Animals 2025-02-04

Background/Objectives: Porcine circovirus type 2 (PCV2) has a major impact on swine productivity. Vaccines are used to aid in control and mitigate production losses. We investigated the protection provided by an intradermal PCV2 vaccine against field strain Taiwan. Methods: conducted safety efficacy study. In study, four Specific Pathogen Free (SPF) piglets were enrolled One was selected as left unvaccinated, one be intradermally vaccinated with five times standard dose (1 mL, Porcilis® PCV...

10.3390/vaccines13040343 article EN cc-by Vaccines 2025-03-24

Porcine circovirus type 2 (PCV2) and Mycoplasma hyopneumoniae (MHP) are both important common pathogens in the pig industry. Both major contributors to porcine respiratory disease complex serve potentiate other bacterial infections such as Actinobacillus pleuropneumonia. This study aims evaluate efficacy of a ready-to-use bivalent PCV2 MHP vaccine field under naturally PCV2-infected farms against existing monovalent options. We evaluated viremia, antibodies, lung lesion scores slaughtered...

10.3390/vetsci12040304 article EN cc-by Veterinary Sciences 2025-03-26

The use of exogenous hormones has long been interest for improving reproductive performance in swine production. Enhancing litter size directly impacts the economic efficiency pig Various strategies, including nutritional, genetic, and hormonal approaches, have explored with varying degrees success. Administering a gonadotropin-releasing hormone (GnRH) agonist, such as buserelin, at onset estrus can induce ovulation reduce variation timing among sows. This study assessed impact GnRH agonist...

10.3390/ani14172501 article EN cc-by Animals 2024-08-28
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