- Substance Abuse Treatment and Outcomes
- Child and Adolescent Psychosocial and Emotional Development
- Homelessness and Social Issues
- Behavioral Health and Interventions
- Mental Health Research Topics
- Cannabis and Cannabinoid Research
- Prenatal Substance Exposure Effects
- Digital Mental Health Interventions
- Smoking Behavior and Cessation
- Functional Brain Connectivity Studies
- Attention Deficit Hyperactivity Disorder
- Alcohol Consumption and Health Effects
- Neurotransmitter Receptor Influence on Behavior
- Mobile Health and mHealth Applications
- Youth Substance Use and School Attendance
- Gambling Behavior and Treatments
- Mental Health Treatment and Access
- LGBTQ Health, Identity, and Policy
- Advanced Neuroimaging Techniques and Applications
- Adolescent Sexual and Reproductive Health
- Bipolar Disorder and Treatment
- Neural and Behavioral Psychology Studies
- Sleep and related disorders
- Health disparities and outcomes
- Early Childhood Education and Development
Rutgers, The State University of New Jersey
1996-2025
Robert Wood Johnson Foundation
2025
Rutgers Sexual and Reproductive Health and Rights
2021-2024
Johnson University
2020-2024
Institute on Aging
2021-2023
University of Pittsburgh
2011-2020
Foundation for Healthcare Advancement
2020
Center for the Neural Basis of Cognition
2019
University of Pittsburgh Medical Center
2009-2018
Michigan State University
2018
Objective: During adolescence, neurobiological maturation occurs concurrently with social and interpersonal changes, including the initiation of alcohol other substance use. The National Consortium on Alcohol NeuroDevelopment in Adolescence (NCANDA) is designed to disentangle complex relationships between onset, escalation, desistance use changes neurocognitive functioning neuromaturation. Method: A sample 831 youth, ages 12–21 years, was recruited at five sites across United States,...
The performance of three brief screens, the CAGE, TWEAK and Alcohol Use Disorders Identification Test (AUDIT), was evaluated against a DSM-IV diagnosis alcohol abuse or dependence in an adolescent sample. Adolescents (13-19 years old) who presented to emergency department for treatment injury, tested negative blood concentration at time admission, were administered structured diagnostic interview modified versions AUDIT. Of 415 adolescents whom complete data available, 18% met criteria use...
Item response theory (IRT) is supplanting classical test as the basis for measures development. This study demonstrated utility of IRT evaluating DSM-IV diagnostic criteria. Data on alcohol, cannabis, and cocaine symptoms from 372 adult clinical participants interviewed with Composite International Diagnostic Interview--Expanded Substance Abuse Module (CIDI-SAM) were analyzed Mplus (B. Muthen & L. Muthen, 1998) MULTILOG (D. Thissen, 1991) software. Tolerance legal problems criteria dropped...
This article reviews literature on the validity and performance characteristics of Diagnostic Statistical Manual Mental Disorders (4th ed.; DSM-IV; American Psychiatric Association, 1994) diagnostic criteria for substance use disorders (SUDs) recommends changes in these that should be considered next edition DSM (DSM-V). Substantial data indicate DSM-IV abuse dependence are not distinct categories SUD best modeled as reflecting a unidimensional continuum substance-problem severity. The...
The Pittsburgh Girls Study is a longitudinal, community–based study of 2,451 girls who were initially recruited when they between the ages 5 and 8 years. primary aim was testing developmental models conduct disorder, major depressive their co-occurrence in girls. In current article, we summarize published findings from past years PGS place those results context what it known to date about psychopathology Key suggest that DSM–IV mental disorders tend have an insidious onset often beginning...
Item response theory (IRT) has advantages over classical test in evaluating diagnostic criteria. In this study, the authors used IRT to characterize psychometric properties of Diagnostic and Statistical Manual Mental Disorders, 4th edition (DSM-IV; American Psychiatric Association, 1994) alcohol cannabis use disorder symptoms among 472 clinical adolescents. For both substances, DSM-IV fit a model specifying unidimensional latent trait problem severity. Threshold (severity) parameters did not...
Brain structural development continues throughout adolescence, when experimentation with alcohol is often initiated. To parse contributions from biological and environmental factors on neurodevelopment, this study used baseline National Consortium Alcohol NeuroDevelopment in Adolescence (NCANDA) magnetic resonance imaging (MRI) data, acquired 674 adolescents meeting no/low or drug use criteria 134 exceeding criteria. Spatial integrity of images across the 5 recruitment sites was assured by...
Binge drinking is associated with numerous negative consequences. The prevalence and intensity of binge highest among young adults. This randomized trial tested the efficacy a 12-week interactive text message intervention to reduce up 6 months after completion Young adult participants (18-25 y; n = 765) above low-risk limits (AUDIT-C score >3/4 women/men), but not seeking alcohol treatment, were enrolled from 4 Emergency Departments (EDs) in Pittsburgh, PA. Participants one three conditions...
Background: This study examined whether the factor structure of a modified version Alcohol Use Disorders Identification Test (AUDIT) represented three intended conceptual domains consumption, dependence symptoms, and alcohol‐related consequences in an adolescent sample. Additionally, utility factor‐specific cut scores identifying patients with DSM‐IV alcohol diagnoses was investigated. Methods: Adolescents treated for injury emergency department who reported use last year ( n = 173; 57%...
Abstract Aims This commentary critically evaluates the use of substance‐related negative psychosocial and health consequences to define diagnose alcohol other substance disorders. Methods Narrative review. Results The cause much suffering are major public economic problems. However, there a number conceptual measurement problems with using as diagnostic criteria for Data indicate that introduce systematic bias degrade validity systems. Conclusions Negative should play fundamentally reduced...