Volume kinetics is a method used for analyzing and simulating the distribution elimination of infusion fluids. Approximately 50 studies describe disposition 0.9% saline, acetated lactated Ringer's solution, based on repeated measurements hemoglobin concentration (sometimes) urinary excretion. The slow to peripheral compartment results in 50-75% larger plasma dilution during an crystalloid fluid than would be expected if had been immediate. A drop arterial pressure induction anesthesia...

Abstract How infusion fluids are distributed and eliminated is of importance to how much fast they should be administered. This manuscript applies population pharmacokinetic modeling intravenous infusions crystalloid fluid, which a common therapy in hospital care mandatory during surgery. The analysis was based on the hemodilution urine output measured after 262 1647 ± 461 mL (mean SD) fluid over 30 min adults. result shows that distribution from plasma interstitial space occurred twice as...

A knowledge of the distribution different fluids given by intravenous infusion is basic to understanding effects fluid therapy. Therefore, a mathematical model was tested analyze volume kinetics three types fluids.The authors infused 25 ml/kg Ringer acetate solution, 5 6% dextran 70 in 0.9% NaCl, and 3 7.5% NaCl over 30 min 8 male volunteers aged from 36 years (mean, 31 years) measured changes total hemoglobin, serum albumin, blood water time. The were expressed as fractioned dilution then...

Background Major differences in plasma volume expansion between infusion fluids are fairly well known, but there is a lack of methods that express their dynamic properties. Therefore, closer description enabled by kinetic modeling presented. Methods Ten healthy male volunteers received, on different occasions, constant-rate intravenous over 30 min consisting 25 ml/kg 0.9% saline, lactated Ringer's solution, acetated 5 7.5% or 3 saline 6% dextran. One-, two-, and three-volume models were...

The amount of Ringer's solution needed to restore normal blood volumes is thought be three five times the volume lost. This therapy can optimized by using a kinetic model that takes accounts for rates distribution and elimination infused fluid.The authors 25 ml/kg acetate into 10 male volunteers who were 23 33 yr old (mean, 28 yr) when they normovolemic after 450 ml 900 had been withdrawn. One-volume two-volume models fitted dilution total venous hemoglobin plasma albumin...

To compare bipolar with the conventional monopolar transurethral resection of prostate (TURP) for blood loss and speed resection.In all, 202 consecutive patients from hospital waiting list were randomized to undergo TURP using either a system (Surgmaster TURis, Olympus, Tokyo, Japan) or (24 F, Storz, Tübingen, Germany). The during after surgery was measured photometer. Other variables compared included indices transfusion rate.There no statistically significant differences in operative...

Abstract Background Volume replacement with crystalloid fluid is the conventional treatment of hemorrhage. We challenged whether a standardized amount 5% or 20% albumin could be viable option to maintain blood volume during surgery associated major Therefore, aim this study was quantify and compare plasma expansion properties albumin, Ringer-lactate, when infused surgery. Methods In single-center randomized controlled trial, therapy combat hypovolemia hemorrhagic phase cystectomy randomly...

Abstract Background Kinetic analysis of crystalloid fluid yields a central distribution volume ( V c ) the same size as expected plasma (approximately 3 L) except during general anesthesia which might be only half large. The present study examined whether this difference is due to influence intravascular albumin balance. Methods A population kinetic according three-compartment model was performed based on retrospective data from 160 infusion experiments 1–2.5 L had been infused intravenously...

Objective To study the effect of graded crystalloid fluid resuscitation on central hemodynamics and outcome after intra-abdominal hemorrhage. Methods Ten minutes a 5-mm long laceration was produced in infrarenal aorta, 32 pigs were randomized to receive either no or Ringer's solution proportion 1:1, 2:1, 3:1 expected amount blood lost per hour (26 mL kg sup -1) over 2 hours. The studied using arterial pulmonary artery catheters four flow probes placed major vessels. Results During first 40...

Objectives To study the central and regional hemodynamics oxygen consumption during acute hypovolemia volume replacement with crystalloid colloid solutions. Design Prospective, randomized, laboratory investigation. Setting Clinical physiology department at a university hospital. Subjects Eighteen healthy male volunteers, between 21 35 yrs of age (mean 26). Interventions Catheters were inserted in cubital vein, brachial artery, pulmonary thoracic aorta, right hepatic left renal vein for...

We evaluated signs and symptoms of the transurethral resection syndrome recorded during after 273 prostatic resections performed at 2 hospitals between 1984 1993. Glycine solution was used as irrigant ethanol served a tracer for fluid absorption. The incidence severity that could possibly be related to increased progressively more glycine absorbed. Patients who absorbed 0 300 ml. had an average 1.3 such symptoms. This number 2.3 when 1,001 2,000 were absorbed, 3.1 2,001 3,000 5.8 volumes...

Biochemical markers for the circadian rhythm were studied in patients treated at ICU (intensive care unit) of two regional hospitals. A normal is characterized by a relatively higher melatonin and lower cortisol excretion night. Disturbances affect sleep, mood cognitive performance. All urine excreted between 07:00 22:00 hours (day) (night) was collected sampled throughout entire period (median, 10 days) 16 6-SMT (6-sulphatoxymelatonin), which metabolite melatonin, free cortisol. The overall...

The absorption of irrigating fluid was measured by the ethanol method every 10 minutes during course 700 transurethral prostatic resections. total blood loss also using a photometer method. We found that determination is convenient monitoring in daily practice. Absorption excess 150 ml. detected 46% operations. volume irrigant absorbed increased with weight removed tissue, operating time and loss. uptake usually started midway through operation. Once had started, there an 87% probability it...

The ethanol concentration in the expired breath (EB–ethanol), volumetric fluid balance and serum sodium were measured course of 60 transurethral resections prostate which irrigating was 1.5% glycine + 1% ethanol. Measurement EB–ethanol indicated absorption irrigant at a rate more than 150 ml 10 min, as volumetrically. There significant direct linear relationship between cumulative volume absorbed (R2 = 0.83); this correlation stronger when duration taken into account 0.90). inversely related...