A5103224270- Corneal surgery and disorders
- Corneal Surgery and Treatments
- Glaucoma and retinal disorders
- Medical and Biological Sciences
- Ocular Surface and Contact Lens
- Advanced Theoretical and Applied Studies in Material Sciences and Geometry
- Ophthalmology and Visual Impairment Studies
Volgograd State Technical University
2023-2024
256 subjects (256 eyes) participated in the study: 174 healthy individuals (174 with normal corneas different refraction and 82 patients (82 keratoconus at stages 1, 2 3. Based on mathematical modeling, biomechanical corneal properties patterns of 2, 3 were evaluated. Mathematical modeling made it possible to determine dimensions degrees local reduction, which depended disease stage practically did not change from shape keratopographic pattern localization.
Abstract Original article Experience in the application of mathematical modeling for predicting outcome treatment progressive keratoconus E.G. Solodkova, S.B. Izmailova, B.E. Malyugin, I.N. Zakharov, V.P. Fokin, S.V. Balalin, E.V. Lobanov, V.A. Sivolobov, V.H. Le S. Fyodorov Eye Microsurgery Federal State Institution, Volgograd branch, Volgograd, Russian Federation Moscow, Technical University, Purpose. To analyze results applying to plan, predict and control effects ultraviolet corneal...
A comparative analysis of corneal saturation with riboflavin solution during standard, modified and transepithelial techniques collagen crosslinking on 15 porcine cadaveric eyes using the histologic method investigation was carried out. The results study confirmed need for de-epithelialization to ensure sufficient cornea solution. Partial de-epithelization in area keratoconus is admissible at carrying out ultraviolet (UV-CXL), because, according histological research, there a spreading into...
The study aims to develop a modified personalized topographically and tomographically oriented technique of ultraviolet corneal collagen cross-linking (UVCXL) affect the area cornea with weakest biomechanical properties as determined by mathematical modeling.Modeling biomechanics keratoconic under conditions external diagnostic action was done using COMSOL Multiphysics® software. Finite-element analysis procured 3D images stress/deformation distribution pattern throughout cornea. Matching...
The aim of this work is to derive a computational technique for model parameter es-timation corneal mechanical behavior basing upon the following input clinical bi-omarkers: real-time amplitude deformations, measured in course non-contact pneumotonometry, intraocular pressure and geometric features patient’s cornea, revealed during his tomographic examination. developed properties prediction within area kerato-conus beyond it, based data resulting from finite element modeling tonometric...
Purpose: To analyze the frequency of main keratotopographic patterns at 1 st , 2 nd and 3 rd stages keratoconus investigate corneal biomechanical properties across different patterns. Methods: The study comprised two stages. first stage was computational-experimental, where we utilized COMSOL Multiphysics® software (COMSOL AB, Stockholm, Sweden) to mathematically model mechanical behavior under intraocular pressure pulsed air jet action in both normal keratoconic conditions. second clinical...
This study is aimed at creation of 3-D geometrical and mechanical finite-element models the cornea numerical analysis its stress-strain state behavior under conditions intraocular pressure external air jet when diagnosing patients different stages keratoconus as well after treatment with corneal collagen cross-linking. There created a model in form spatial segment thin-shell convex structure where shell thickness variable anterior posterior surfaces determined arbitrarily by extrapolation...
This study is aimed at creation of 3-D geometrical and mechanical finite-element models the cornea numerical analysis its stress-strain state behavior under conditions intraocular pressure external air jet when diagnosing patients different stages keratoconus as well after treatment with corneal collagen cross-linking. There created a model in form spatial segment thin-shell convex structure where shell thickness variable anterior posterior surfaces determined arbitrarily by extrapolation...