- Gut microbiota and health
- Eosinophilic Esophagitis
- Infant Nutrition and Health
- Food Allergy and Anaphylaxis Research
- Infant Health and Development
- Liver Disease Diagnosis and Treatment
- Clostridium difficile and Clostridium perfringens research
- Probiotics and Fermented Foods
- Eosinophilic Disorders and Syndromes
- Drug Transport and Resistance Mechanisms
- Pediatric health and respiratory diseases
- Yersinia bacterium, plague, ectoparasites research
- Urticaria and Related Conditions
- Asthma and respiratory diseases
- Breastfeeding Practices and Influences
- Viral gastroenteritis research and epidemiology
- Metabolomics and Mass Spectrometry Studies
- Diet and metabolism studies
- Diet, Metabolism, and Disease
- Contact Dermatitis and Allergies
- Liver Diseases and Immunity
Russian Medical Academy of Continuous Professional Education
2022-2024
City Clinical Hospital
2024
Tver State Medical University
2024
Ministry of Health of the Russian Federation
2024
Russian Children's Clinical Hospital
2024
Ministry of Health
2024
Children's City Clinical Hospital №11
2024
Pirogov Russian National Research Medical University
2021
Cow's milk protein allergy (CMPA) is one of the urgent problems modern health care, which pediatricians often encounter in their practice. CMPA imposes a burden on babies and mothers, forcing them to limit diet plan family budget, taking into account cost therapeutic infant formulas. Also, still challenging diagnosis since it can present three variants has various developing mechanisms. The elimination most reliable test an with suspected CMPA. All dietary restrictions are imposed mother if...
Gut microbiota is one of the main components that influence human health status. The gut microflora begins to establish as early prenatal period, however, most intensive colonization infant by maternal and environment microorganisms occurs during intranatal postnatal periods. mother-placenta-fetus system lays foundation for formation microbiota. starts changing pregnancy in order modify metabolism make it more favourable fetus, continues throughout pregnancy, influencing incubation fetus's...
The possibilities of ursodeoxycholic acid (UDCA) application in clinical practice are evaluated. Statistical analysis data from modern Russian and foreign literature sources, as well recent scientific works the field pharmacology UDCA was carried out. has a significant potential, it can affect both body whole its individual organs, systems processes. This effect is realized either by immunomodulating properties or directly on cells themselves through bile receptors (bile acids together with...
The prevalence of allergic diseases is increasing at rates corresponding to epidemic’s spread rates. Cow’s milk protein allergy (CMPA) one the most common food allergies in infancy. Its clinical variants remain hard-to-diagnose due their multiple faces. Food can develop along pathway associated with both IgE and non-IgE, or mixed one. Non-IgEassociated allergies, lack accurate specific laboratory markers, cause significant difficulties making a diagnosis. search for new diagnostic markers...
The article is devoted to a review of the literature on study intestinal microbiota in chronic viral hepatitis children. results recent studies microbial diversity colon contents using 16S ribosomal RNA sequencing are presented. Scientific research years has proven influence changes and its individual representatives formation complications patients with hepatitis, development fibrosis/cirrhosis. Changed quantitative species ratios microorganisms can lead launch pathological reactions...
The prevalence of food allergies continues to grow steadily, and due certain difficulties in diagnosing not associated with immunoglobulin E, some conditions are little known. Such diagnosis-challenging diseases include protein-induced enterocolitis syndrome (FPIES), a relatively low-prevalence disease most commonly occurring early childhood but, cases, affecting adults as well. pathogenesis FPIES has been reliably studied. is elevated serum tryptase release pro-inflammatory cytokines,...
Breast milk is the gold standard for infant feeding. In case of its lack or insufficiency, this brings up question about an affordable and adequate alternative. Adapted cow’s formulas are most commonly used, but incidence protein allergy in young children increasing worldwide. Given early onset gastrointestinal disorders infants, minimal digestive dysfunctions often interpreted by doctors as sensitization to proteins functional disorders. However, there conditions associated not with...
Aim. To analyze current data on epidemiology, pathophysiology of eosinophilic gastrointestinal diseases (EGID) in children with focus small intestinal affection. Key points. EGID are inflammatory conditions the tract, characterized by tissue eosinophilia a depth organ damage from mucous layer to muscular and serous layer, resulting severe their structure function. Importance food allergy is still underestimated, although it affects about 5% up 3–4% adults. Eosinophilic digestive tract...
The gut microbiota is a complex collection of bacteria, viruses, protozoa, archaea, and fungi colonising the human gastrointestinal (GI) tract. plays fundamental role in keeping body healthy development various diseases, including mental ones. Clinical studies have showed that there exists bidirectional communication between gut, brain within brain-gut-microbiome axis. It understood microbes play many disorders may be potential therapeutic target. nervous system GI tract communicate through...
Today, as in ancient times, diarrhea (loss of water and electrolytes along with stool) accompanies many pathological conditions humans. The pathophysiology various types has been studied, which made it possible to optimize therapeutic approaches save the lives people. most dangerous occur young patients osmotic exudative diarrhea, they result exicosis within a short time. In arriving at diagnosis, rehydration therapy should be started soon possible. article presents historical aspects...