A5074650715- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Neonatal Respiratory Health Research
- Human Health and Disease
- Kawasaki Disease and Coronary Complications
- Child and Adolescent Health
- Pediatric Urology and Nephrology Studies
- Eosinophilic Esophagitis
- COVID-19 Impact on Reproduction
- COVID-19 and Mental Health
- Pediatric health and respiratory diseases
- Congenital Diaphragmatic Hernia Studies
- Respiratory viral infections research
- Infant Nutrition and Health
- Infant Development and Preterm Care
- Inflammasome and immune disorders
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Microscopic Colitis
- Neuroendocrine Tumor Research Advances
- Urinary Tract Infections Management
- Healthcare Systems and Public Health
- Genetic and Kidney Cyst Diseases
- Vascular Malformations and Hemangiomas
- Pneumonia and Respiratory Infections
Pirogov Russian National Research Medical University
2012-2024
Children's City Clinical Hospital №11
2020-2024
City Clinical Hospital
2015-2024
City Children's Hospital No. 22
2021
Ministry of Health of the Russian Federation
2018
The long-term sequelae of coronavirus disease 2019 (COVID-19) in children remain poorly characterised. This study aimed to assess outcomes previously hospitalised with COVID-19 and associated risk factors.This is a prospective cohort (≤18 years old) admitted hospital confirmed COVID-19. Children between 2 April 2020 26 August were included. Telephone interviews used the International Severe Acute Respiratory Emerging Infection Consortium (ISARIC) Health Wellbeing Follow-up Survey for...
Previous studies assessing the prevalence of COVID-19 sequelae in adults and children were performed absence an agreed definition. We investigated post-COVID-19 condition (PCC) (WHO definition), at 6- 12-months follow-up, amongst previously hospitalised assessed risk factors.Prospective cohort study with confirmed Moscow, between April August, 2020. Two follow-up telephone interviews, using International Severe Acute Respiratory Emerging Infection Consortium survey, 6 12 months after...
While much of the attention on COVID-19 pandemic was directed at daily counts cases and those with serious disease overwhelming health services, increasingly, reports have appeared people who experience debilitating symptoms after initial infection. This is popularly known as long COVID.
Background The long-term sequelae of coronavirus disease 2019 (Covid-19) in children remain poorly characterised. This study aimed to assess outcomes previously hospitalised with Covid-19 and associated risk factors. Methods is a prospective cohort (18 years old younger) admitted confirmed Z.A. Bashlyaeva Children's Municipal Clinical Hospital Moscow, Russia. Children the hospital during first wave pandemic, between April 2, 2020 August 26, 2020, were included. Telephone interview using...
Background: Many people experience prolonged consequences of COVID-19, but studies assessing the prevalence COVID-19 sequelae in adults and children have been performed absence an agreed definition. Our objective was to investigate post-COVID-19 condition (as per WHO definition), at 6- 12-months follow-up, among previously hospitalised assess risk factors.Methods: Prospective cohort study with confirmed Moscow who were between April August, 2020. Two follow-up telephone interviews, using...
Abstract Background Long-term health outcomes in children and young people (CYP) after COVID-19 infection are not well understood studies with control groups exposed to other infections lacking. This study aimed investigate the incidence of post-COVID-19 condition (PCC) incomplete recovery CYP hospital discharge compare between different SARS-CoV-2 variants non-SARS-CoV-2 infections. Methods A prospective exposure-stratified cohort individuals under 18 years old Moscow, Russia. Exposed...
To protect young individuals against SARS-CoV-2 infection, we conducted an open-label, prospective, non-randomised dose-escalation Phase 1/2 clinical trial to evaluate the immunogenicity and safety of prime-boost “Sputnik V” vaccine administered at 1/10 1/5 doses adolescents aged 12–17 years. The study began with vaccination older cohort (15-to-17-year-old participants) lower (1/10) dose then expanded whole group (12-to-17-year-old participants). Next, was used according same scheme. Both...
The heavy burden of meningococcal infection is associated not only with life-threatening complications in the acute period and high mortality invasive forms disease, but also severe consequences survivors, who are recorded our country.The aim study: to analyze clinical manifestations, outcomes disease children various regions Russian Federation.Materials methods: an analysis data from 1327 inpatient medical records 14 regional centers Federation for 2012-2021 was carried out (28.3% cases...
This study aimed to estimate the impact of COVID-19 pandemic on circulation non-SARS-CoV-2 respiratory viruses and clinical characteristics in hospitalized children.A total 226 864 children admitted Children's City Clinical Hospital with acute infection September November 2018 2020 Moscow were tested for using multiplex polymerase chain reaction (PCR) Mycoplasma pneumoniae/Chlamydia pneumoniae enzyme-linked immunosorbent assay.The detection rate was lower than 2018, 16.9% versus 37.6%. An...
Post-covid syndrome (PCS) is a symptom complex that occurs during and after COVID-19 lasting more than 12 weeks, which not possible disease. The clinical manifestations of PCS are many-sided, under their mask or exacerbations chronic organic activity, the trigger was virus, hidden. diagnosis exclusion. main PCS: autonomic dysregulation, cognitive psycho-emotional disorders, disorders respiratory system, cardiovascular, digestive systems. Direct pathogenic factors, neurological preservation...
Objective. To determine the frequency, range of triggers, features clinical symptoms and treatment anaphylaxis in children hospitalized with severe systemic allergic reactions pediatric department Moscow. Patients methods. We conducted a retrospective analysis 1197 medical records admitted to Z.A.Bashlyaeva Children's City Clinical Hospital over period from 2016 2020 criteria for anaphylaxis. The diagnosis was made retrospectively 86 patients based on corresponding reports 2 independent...
Acute appendicitis is the most common surgical pathology in paediatric practice. Surgical interventions children with acute and complicated are performed when urgently indicated at various stages of disease. Laparoscopic appendectomy has become current “gold standard” for providing emergency surgery care to children. Improvements techniques post-operative protocols have reduced complications 5–7%. The discussion topics include issues argumentation “incidental appendectomies” be minimal...
Purpose: to identify the features of COVID-19 infection in children at different periods epidemiological rise incidence city Moscow. Results. The article presents observation 1561 hospitalized State Medical Institution «Children's City Clinical Hospital named after Z. A. Bash-lyaeva DZM» with a diagnosis new coronavirus during rises morbidity («2nd and 3rd waves COVID-19»). An increase number «3rd wave COVID-19», early admission dates from onset disease, due lack treatment effect outpatient...
Studies on the myocardial fibrosis are a new direction in sports medicine. Much data indicate formation of hypertrophy, as natural response to systematic physical activity, while development this category people is not entirely explainable. Modern imaging methods, including magnetic resonance imaging, make it possible identify different variants subclinical fibrosis. The article discusses remodeling and formation, depending type its mechanisms, well early diagnosis methods applicable...
With antibiotic resistance increasing and new microbial factors forming, the problem of creating methods to treat prevent urinary tract infections becomes topical. The latest studies showed that urothelium contains a large number immune providing its protection against adverse effects various uropathogens in vivo. There are very promising molecules – antimicrobial peptides (AMPs) terms further therapeutic use among components inborn immunity. AMPs evolutionarily oldest innate article...
The new coronavirus infection (COVID‑19) caused by the SARS-CoV‑2 is rightfully recognized as a pandemic of 21st century and poses threat to health all human race. According World Health Organization, at October 4, 2020, were registered worldwide 34,804,348 confirmed cases COVID‑19, including 1,030,738 deaths. currently available data, children accounted for 1 5% patients diagnosed with COVID‑19 [4]. Children aged between 10–18 years dominated (45.9%), first life 26.1%. At same time, over...
The global prevalence of tobacco and nicotine-containing product use has now reached epidemic proportions, a problem particularly relevant when it comes to adolescents. Major trends in the among adolescents include flattening gender differences, decreasing age initiation smoking, emergence alternative uses products. main provisions book devoted prevention children teenagers as present time, edited by professors N.A. Geppe, I.M. Osmanov, N.F. Gerasimenko with participation large group...
Neuroendocrine cell hyperplasia of infancy (NEHI) is a rare interstitial lung disease in children. The clinical features the are characterized by tachypnea, moist rales/crepitus, retraction compliant chest areas and delayed weight gain. diagnosed using NEHI scale coupled with computed tomography organs. manifestations regress as child grows, but may persist up to age 10 y/o. purpose research was characterize course including COVID-19 impact passive smoking children below 8 Materials methods:...
The preservation of the human urinary tract integrity in interaction with microorganisms depends on balance many components: viability nonspecific protective factors mucosa, virulence microorganisms, intensity innate immune response tissue to presence mutual impact microand macro-organism upon each other that is directed towards creation a normal microbiome, and not inflammation. Most these are genetically determined both by humans. article presents modern data Russian foreign literature...
The article analyses the data published from January 2020 to April 25, in print media or available on official websites of peer-reviewed medical sources (pre print), international and national professional communities, state regulatory authorities dedicated epidemiological clinical laboratory features new coronavirus infection newborns, infants older children. authors have concluded that currently there are no convincing vertical transmission infection. At same time, they found is a risk...
Cow's milk protein allergy (CMPA) is one of the urgent problems modern health care, which pediatricians often encounter in their practice. CMPA imposes a burden on babies and mothers, forcing them to limit diet plan family budget, taking into account cost therapeutic infant formulas. Also, still challenging diagnosis since it can present three variants has various developing mechanisms. The elimination most reliable test an with suspected CMPA. All dietary restrictions are imposed mother if...
Lower extremities deformation is observed quite often in infants. One of the Blount's disease diagnosis features difficulty its differential when excluded from other conditions such as rickets, rickets-like diseases and physiological curvature lower Article represents main diagnostic criteria for abovementioned diseases. A clinical case a patient with who had deviations calcium-phosphorus metabolism that their turn are uncommon this pathology described. The entire set laboratory signs...
Introduction. Serologic tests are the main tool to screen for celiac disease. The serologic tissue transglutaminase (tTG-IgA) antibodies combined with assessment of total serum IgA concentration is recommended as a primary test. Other serological markers, in particular and/or IgG against deamidated gliadin peptides (DGP-IgG/IgA) and native (AGA-IgA/IgG), not use diagnosing disease immunocompetent patients. Aim. To determine diagnostic value markers during initial examination children....
Background. Currently, the effectiveness of various screening programs for celiac disease remains a matter debate. According to most researchers, selective among patients with characteristic symptoms or at-risk groups is effective. Aim. To evaluate in gastrointestinal symptoms. Materials and methods. In an open retrospective clinical study, rate 1,482 children who were examined Bashlyaeva Children's City Clinical Hospital significant depending on age identified. Results. The mean was 8.26%:...