А.Л. Заплатников

ORCID: 0000-0003-1303-8318
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About
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Research Areas
  • Pediatric health and respiratory diseases
  • Respiratory viral infections research
  • Influenza Virus Research Studies
  • Human Health and Disease
  • Infant Nutrition and Health
  • Neonatal Respiratory Health Research
  • Pneumonia and Respiratory Infections
  • Respiratory and Cough-Related Research
  • Vitamin D Research Studies
  • Child and Adolescent Health
  • Breastfeeding Practices and Influences
  • Digestive system and related health
  • Viral gastroenteritis research and epidemiology
  • Immune responses and vaccinations
  • Hematological disorders and diagnostics
  • Chemical and Physical Studies
  • Streptococcal Infections and Treatments
  • Hepatitis Viruses Studies and Epidemiology
  • Iron Metabolism and Disorders
  • Sepsis Diagnosis and Treatment
  • Poisoning and overdose treatments
  • Asthma and respiratory diseases
  • Infectious Encephalopathies and Encephalitis
  • Restraint-Related Deaths
  • Healthcare Systems and Public Health

Russian Medical Academy of Continuous Professional Education
2002-2025

Ministry of Health of the Russian Federation
2019-2021

Ministry of Health
2020

Russian Children's Clinical Hospital
2019-2020

City Clinical Hospital
2019-2020

Federal Agency for Health and Social Development
2007-2008

Drug fever is a febrile reaction that coincides in time with and pathogenetically associated the use of drug. The review presents publications epidemiological clinical studies on various variants development due to pharmacological agents. Febrile reactions both immune hypersensitivity those other mechanisms development, as well drug syndromes, including one syndromes (drug-induced syndrome, serum sickness, drug-induced lupus), are considered. Most often, term “drug fever” used define cases...

10.21518/ms2025-095 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2025-04-05

The implementation of clinical guidelines in daily practice has not made the desired progress as yet and is restrained by various factors, a significant part which are subjective. leading factor among them that doctors underestimated practical benefits their use settings. Antibiotic indications for most common acute bacterial infectious inflammatory respiratory diseases, such streptococcal tonsillitis/pharyngitis, purulent otitis media, community-acquired pneumonia, sinusitis, presented...

10.21518/ms2025-092 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2025-04-04

The surveillance of influenza viruses in ARVI structure and study their properties epidemic season 2019-2020 Russian Federation are actual for investigations due to tasks Global Influenza Strategy initiated by WHO 2019.The data epidemiological on influenza- ARVI-associated morbidity hospitalization different age groups population were analyzed; virological, genetic statistical methods used.Preschool children involved the most. Meanwhile, highest rate was observed patients 18-40 years old....

10.36233/0507-4088-2020-65-6-4 article EN cc-by Problems of Virology 2021-01-07

Clinical case observation of a deadly poisoning with flammable fluid used to accelerate the ignition charcoal in barbecue grill two years old boy and brief bibliographical overview dedicated it are presented Article. Unfortunate poisonings by hydrocarbons that products oil refining common Worldwide, mainly among children under 5 old. Flammable grill, which is mixture extreme hydrocarbons, not an uncommon cause Russia though. A was hospitalized ICU regional children’s hospital just some 2...

10.24110/0031-403x-2024-103-1-184-189 article EN PEDIATRIA Journal named after G N SPERANSKY 2024-02-14

This article discusses negative effects of vitamin D deficiency on low birthweight preterm and full-term newborns. Results the studies provision to pregnant women their newborn children are addressed. Vitamin is highly prevalent in It was demonstrated that inadequate antenatal a fetus with may result congenital rickets neonatal seizures due hypocalcemia newborns also accounts for increased rates necrotic enterocolitis, bronchopulmonary dys-plasia, impaired growth development as well higher...

10.32364/2618-8430-2020-3-2-142-148 article EN Russian Journal of Woman and Child Health 2020-01-01

This literature review aims to provide an update on the problem of coronavirus infection in children. It covers specific features pathogens and ways their transmission children focuses nuances clinical course. also describes approaches diagnosis, treatment, prevention seasonal infections COVID-19. Particular attention is paid treatment acute respiratory viral (ARVIs), including infections, during ongoing COVID-19 pandemic using Anaferon for children, a drug with immune-mediated antiviral...

10.20953/1817-7646-2020-5-73-86 article EN Voprosy praktičeskoj pediatrii 2020-01-01

In recent years, pediatricians and epidemiologists have noted the emergence of some unfavorable trends in child population health, namely: an increase number allergic pathologies, autoimmune diseases, obesity, chronic nonspecific bowel diseases. Among risk factors, changes composition intestinal microbiota occupy one first places. This review discusses numerous mechanisms to explain how gut bacteria can be interconnected with immunity or development concomitant The article describes detail...

10.32364/2618-8430-2023-6-2-184-191 article EN cc-by Russian Journal of Woman and Child Health 2023-01-01

Aim: to assess the landscape of pneumococcus serotypes among children organized in kindergarten groups Khanty-Mansiysk city. Patients and Methods: study included 510 (2-6 years old) attending kindergartens The were divided into 2 groups: vaccinated (n=50) non-vaccinated against pneumococcal infection (n=460). data on vaccination status received from prophylactic immunization records (Form 063/u) child's medical 112/u). In addition, following analysed: age, gender, gestation age at birth,...

10.32364/2618-8430-2023-6-2-164-168 article EN cc-by Russian Journal of Woman and Child Health 2023-01-01

The literature review presents current knowledge of risk factors, etiology, the main links immunopathogenesis, clinical manifestations and laboratory guidelines for neonatal sepsis (NS). It is emphasized that NS remains a serious health problem. At same time, it specified incidence rates early HS in children born prematurely are 60 times higher than fullterm children, mortality 16.6 higher. was also noted frequency late with an increase body weight at birth from 500 g to 2500 decreases 51.2%...

10.24110/0031-403x-2022-101-1-140-148 article EN PEDIATRIA Journal named after G N SPERANSKY 2022-01-23

Журнал для непрерывного медицинского образования врачей Ребенок, рожденный путем операции кесарева сечения: риски здоровья и возможности их минимизации АНАЛИТИЧЕСКИЕ ОБЗОРЫ 1 Общество с ограниченной ответственностью «Нестле Россия», 115054, г.Москва, Российская Федерация 2 Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального «Российская медицинская академия

10.33029/2308-2402-2020-8-2-28-38 article RU Neonatology News Opinions Training 2020-01-01

This paper reviews the effects of vitamin D deficiency on pregnant women and newborns. It was demonstrated that in is associated with higher risks threatened preterm labor, placental insufficiency, preeclampsia, gestational diabetes, bacterial vaginosis, impaired uterine contractility as well rate C-sections. Vitamin insufficiency newborns inadequate bone mineralization also results metabolic disorders, hypocalcemic seizures, bronchopulmonary dysplasia, necrotic enterocolitis, sepsis, mental...

10.32364/2618-8430-2020-3-3-174-181 article EN cc-by Russian Journal of Woman and Child Health 2020-01-01

This paper addresses published data on therapeutic, preventive efficacy, and safety of bacterial lysates (BLs) in pediatric practice. Studies the mechanisms action BLs are discussed. Experimental evidence demonstrates that effect is maintained even high level lysis characterized by presence only small peptides or their fragments without antigenic properties. The authors discuss potential involvement development trained immunity, whose effects last less time than a conventional...

10.32364/2618-8430-2021-4-3-284-291 article EN cc-by Russian Journal of Woman and Child Health 2021-01-01

In the article authors consider problem of diagnostics causes, development mechanisms and algorithm for treatment fevers in children. Indications use fever reducing medicines are discussed. Data Russian researchers to prove feasibility effectiveness symptoms by drug Ibuclin Junior provided.

10.21518/2079-701x-2017-1-212-218 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2017-01-01

Although bronchial asthma is a widespread disease in pediatric population, physicians still face difficulties early diagnostics of preschool children due to high frequency obstruction this age group. This article covers key points the resolution adopted by Panel Experts Pediatric Respiratory Society regarding standardization approach and therapy broncho-obstructive conditions, considering cause disease, child's condition severity, as well place nebulized budesonide suspension maintenance...

10.21508/1027-4065-2018-63-3-124-132 article EN cc-by Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 2018-06-29

Relevance: immunotropic effects of cholecalciferol are caused by vitamin-D-induced synthesis antimicrobial peptides (AMP), in particular р-defensins. There very few studies pediatric clinical practice confirming the effect vitamin D availability on AMP synthesis. Aim: analysis correlation between and production assessment medication intake defensin young children. Materials methods : 108 healthy children aged 1 month to 3 years were examined, which 34 (31.5%) adequately provided with...

10.21518/2079-701x-2020-1-158-169 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2020-03-09

The article analyses the data published from January 2020 to April 25, in print media or available on official websites of peer-reviewed medical sources (pre print), international and national professional communities, state regulatory authorities dedicated epidemiological clinical laboratory features new coronavirus infection newborns, infants older children. authors have concluded that currently there are no convincing vertical transmission infection. At same time, they found is a risk...

10.21508/1027-4065-2020-65-3-11-17 article EN Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 2020-07-08

Acute respiratory infections (ARIs) are the most common reason of outpatient visits for internal medicine ambulatory care. As a rule, ARIs induced by various serotypes viruses that cause diseases with very similar clinical symptoms and, thus, it is impossible to make an accurate etiological diagnosis. At same time, therapeutic approaches usually and include impact on different pathogenetic components inflammation process which, among other things, can be achieved using herbal medicinal...

10.32364/2587-6821-2022-6-8-419-426 article EN cc-by Russian Medical Inquiry 2022-01-01

The novel coronavirus disease (COVID-19) pandemic has become a strength test for the national healthcare systems and medical professional communities. gave revealing insight into provision of resuscitation care, shortage personnel protective equipment, lack effective drugs to treat novel, poorly studied infection. Objective. To identify attitude towards immunoprophylaxis in general against infection particular among students pediatricians assess dynamics compliance vaccination these groups....

10.21518/2079-701x-2021-11-202-209 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2021-08-12

Aim: to evaluate the efficacy and safety of Anaferon for children prevention treatment acute respiratory viral infections (ARVI)/influenza using meta-analysis. Patients Methods: meta-analysis included data from 11 randomized clinical trials (RCTs) involving 3079 patients aged 1 month 69 years, which: 1729 people were in preventive drugs efficacy, 1550 — therapeutic children. The evaluation was conducted according criteria "disease duration" and/or "fever duration", criterion "the proportion...

10.32364/2587-6821-2021-5-5-335-347 article EN cc-by Russian Medical Inquiry 2021-01-01
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