A5087389883- Pediatric health and respiratory diseases
- Respiratory and Cough-Related Research
- Asthma and respiratory diseases
- Inhalation and Respiratory Drug Delivery
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Herbal Medicine Research Studies
- Human Health and Disease
- Child and Adolescent Health
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Retinal Development and Disorders
- Pharmaceutical studies and practices
- Thermal Regulation in Medicine
- Influenza Virus Research Studies
- Gastroesophageal reflux and treatments
- Airway Management and Intubation Techniques
- Infant Health and Development
- High Altitude and Hypoxia
- Long-Term Effects of COVID-19
- Allergic Rhinitis and Sensitization
- Seaweed-derived Bioactive Compounds
- Foreign Body Medical Cases
- Redox biology and oxidative stress
Sechenov University
2016-2025
Institute of Cytology and Genetics
2010-2020
Siberian Branch of the Russian Academy of Sciences
2010-2013
Lomonosov Moscow State University
2010
Pathogenesis of age-related macular degeneration (AMD), the leading cause blindness in world, remains poorly understood. This makes it necessary to create animal models for studying AMD pathogenesis and design new therapeutic approaches. Here we showed that retinopathy OXYS rats is similar human according clinical signs, morphology, vascular endothelium growth factor (VEGF) pigment epithelium-derived (PEDF) genes expression. Clinical signs manifest by age 3 months against background...
An acute cough that develops against the background of a respiratory viral infection is most common symptom in childhood. It can significantly affect quality life patients and their families. Currently, there growing interest using natural remedies to treat this type cough. To solve problem, many medicines based on natural, including herbal raw materials, be successfully used. The article demonstrates possibilities some treatment children. Ivy leaf extract (Hedera helix L.) occupies special...
Electron microscopic study of cardiomyocytes taken from healthy Wistar and OXYS rats naked mole (
ω-3 polyunsaturated fatty acids (PUFAs) are incorporated in cell membranes and play an important role the development functioning of organs. Consolidation data on PUFAs child may increase professional's awareness, help to plan clinical studies, develop recommendations for supplementation.
Every year, a seasonal increase in the incidence of respiratory infections is registered Russian Federation, primarily among children. It significantly increases burden on outpatient pediatric service. especially important to optimize daily practice pediatricians by developing algorithms and updating treatment protocols, as well creating conducting training programs. Fever leading symptom acute viral one most common reasons for seeking help services. Leading experts field therapy pediatrics...
Bronchial asthma (BA) is a disease that one of the most frequent chronic diseases childhood. Characteristic clinical symptoms BA are wheezing, cough, difficulty in breathing, shortness breath and, course, recurrent episodes bronchial obstruction. They require mandatory clarification family and individual allergoanamnesis, assessment symptoms, differential diagnosis with other may occur BA. The Global Initiative for Treatment Prevention Asthma (GINA 20202021) preserves develops ageappropriate...
Клиническая иммунология
Cough is one of the most common reasons for seeking medical care and may be manifestations respiratory tract pathology various extrapulmonary diseases. Given diversity causes cough, individualized approach to differential diagnosis rational purpose antitussive therapy required. Agents plant origin used in treatment differ composition, mechanism action, forms production; their modern production must accompanied by strict control collection, storage processing raw materials. The syrup Eucabal...
Although bronchial asthma is a widespread disease in pediatric population, physicians still face difficulties early diagnostics of preschool children due to high frequency obstruction this age group. This article covers key points the resolution adopted by Panel Experts Pediatric Respiratory Society regarding standardization approach and therapy broncho-obstructive conditions, considering cause disease, child's condition severity, as well place nebulized budesonide suspension maintenance...
Acute tonsillopharyngitis (ATP) is a very common disease in children. In non-streptococcal ATP, systemic antibiotics are usually not indicated, but topical antimicrobial therapy advisable.To evaluate the effectiveness of combination cetylpyridinium chloride with gramicidin C form spray children ATP prospective multicenter non-interventional study.Patients and methods. The study included 94 patients aged 6-15 years ATP. A standard examination, assessment pain intensity throat using visual...
Introduction. Cough is the most common manifestation of respiratory infections upper and lower tract indicates impaired mucociliary clearance. The cause cough must be determined to choose management tactics for children with cough. commonly used mucoactive drugs liquefy sputum as a result direct action components on tracheobronchial secretion and/or mucosa tract. Given effect hypertonic salines, we conducted an open clinical study effectiveness 3% saline hyaluronic acid in acute bronchitis...
Introduction. The relevance of studying community-acquired pneumonia in children is associated with its high prevalence, despite timely prevention and effective approaches to the treatment respiratory diseases. Factors influencing severity are diverse include comorbid pathology, early age child, state immune system, etc. Objective. To identify rank risk factors for severe infants preschool children. Materials methods. This article presents results a retrospective analysis 291 medical...
Introduction. Cough is the most common manifestation of respiratory infections affecting upper and lower airways, indicating impaired mucociliary clearance. Mucolytic agents are often used to normalize patient's condition improve mucus To clearance, mucolytic used. Considering action hypertonic solutions, we conducted a comparative clinical study evaluate efficacy safety combination 3% saline solution high molecular weight hyaluronic acid 0.01% (Ingasalin® 3%) in treatment acute bronchitis...
The possibility of preventing episodes bronchial obstruction (BO) in order to reduce the risk asthma formation attracts attention many researchers and doctors. Ammonium glycyrrhizinate (Reglisam, "VIFITECH") is practical interest search for promising anti-inflammatory drugs this matter. Patients methods. study involved 110 children aged 3 7 years with symptoms acute obstructive bronchitis, who had a history at least 2 BO previous 6 months. Formed: comparison group (n = 30) – received...
Due to the high prevalence of community-acquired pneumonia (CAP), study new diagnostic methods for this disease remains relevant. In recent years, ultrasound examination lungs has increasingly attracted attention Russian and foreign researchers. This article presents a series clinical cases with highest reliability significance method. The goal presenting these was describe "findings" on lung different etiology CAP. all presented cases, bilateral changes were revealed, including B-lines,...
The safety of drug therapy is particular importance for immunocompromised patients. This aspect acquires high in the context choosing tactics prevention and treatment acute respiratory viral infections. review presents data on features antiviral immune response common cold/influenza patients with a burdened allergic history brief overview results clinical studies effectiveness innovative biological drugs based antibodies to targets – Ergoferon, Anaferon children Anaferon. have targeted...
Asthma is the most common chronic respiratory disease of childhood worldwide with around 10% children and young adults affected. Despite high prevalence, paediatric asthma treatment outcomes are inadequate, there several avoidable deaths each year. Uncontrolled in population remains a major challenge worldwide, continues to impose significant economic burden, has negative impact on quality life (QOL) patients their families. Effective management involves holistic approach addressing both...
Introduction . Chronic allergic respiratory inflammation triggered by contact with cause-significant allergens is the pathogenetic characteristic of atopic bronchial asthma. Identification sensitization essential for successful therapy Aim To study age-related changes in spectrum to children asthma followed up healthcare facilities Moscow and region. Materials methods A total 970 aged 0 17 years 11 months residing region were include retrospective, cross-sectional, population-based based on...
Objective. To evaluate the efficacy and safety of Raphamin® in treatment acute respiratory viral infections (ARVI) children. Patients methods. A multicenter, double-blind, placebo-controlled, randomized study was conducted an outpatient setting. Of 435 children 12-18 years old with examined, 420 patients who met eligibility criteria were included (n = 420), 1:1 into group 1 (Raphamin®, n 206) 2 (placebo, 214). Treatment 5 days follow-up up to 14 days. Time resolution symptoms infection...
Acute respiratory viral infections (ARVI) are the most common diseases among children. The typical and disturbing symptoms of ARVI nasal discharge, congestion difficulty in breathing. Local protective factors mucosa (epithelial barrier, mucociliary clearance, antimicrobial peptides, immunoglobulin A, microbiota) prevent penetration infections. To children it is important to maintain physiological state mucous membrane. treatment based on care supportive activities. By irrigating cavity with...
Acute respiratory tract infections accompanied by cough play a significant role in pathology childhood. The incidence of acute among children is 4–5 times higher than the adult population and accounts for more 90% all infectious parasitic diseases registered Russia. highest rates are observed preschool age, especially first three years life. As adults, children’s cough, described as symptom «upper infection» or «acute bronchitis», most commonly diagnosed manifestation primary care. These 2...