О. В. Шамшева

ORCID: 0000-0002-6033-6695
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About
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Research Areas
  • Pediatric health and respiratory diseases
  • Respiratory viral infections research
  • Hepatitis Viruses Studies and Epidemiology
  • Viral gastroenteritis research and epidemiology
  • Human Health and Disease
  • Bacterial Infections and Vaccines
  • Yersinia bacterium, plague, ectoparasites research
  • Herpesvirus Infections and Treatments
  • Pneumonia and Respiratory Infections
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Vectors
  • Hepatitis B Virus Studies
  • Vector-borne infectious diseases
  • Respiratory and Cough-Related Research
  • Influenza Virus Research Studies
  • Vaccine Coverage and Hesitancy
  • Immunodeficiency and Autoimmune Disorders
  • Foreign Language Teaching Methods
  • Virology and Viral Diseases
  • Bartonella species infections research
  • Zoonotic diseases and public health
  • Clostridium difficile and Clostridium perfringens research
  • Microbial infections and disease research
  • Chemical and Physical Studies
  • Long-Term Effects of COVID-19

Pirogov Russian National Research Medical University
2011-2025

Ministry of Health of the Russian Federation
2015-2024

30 января 2020 года Всемирная Организация Здравоохранения (ВОЗ) признала вспышку коронавирусной инфекции в Китае чрезвычайной ситуацией области общественного здравоохранения, имеющую международное значение. Генеральный директор ВОЗ Тедрос Адханом Гебрейесус после совещания чрезвычайного комитета Женеве заявил «Я объявляю международную чрезвычайную ситуацию здравоохранения из-за глобальной вспышки коронавируса». В классификации такими ситуациями считаются «экстраординарные события, которые...

10.22627/2072-8107-2020-19-1-5-6 article RU cc-by CHILDREN INFECTIONS 2020-03-28

The relevance of the problem whooping cough in newborns is due to severity clinical manifestations and high mortality. aim work present data available literature on causes unfavorable course newborns, illustrated by our own examples, as well summarize ways solve this problem. Materials methods : a review domestic foreign over past 10 years, including Internet resources, was conducted observations with are presented. Conclusion . Whooping children first months life develops absence maternal...

10.22627/2072-8107-2025-24-1-33-36 article EN cc-by CHILDREN INFECTIONS 2025-03-21

Согласно данным Всемирной организации здравоохранения, в мире насчитывается около 300 миллионов человек с хроническим гепатитом В, при этом ежегодно происходит 1,5 миллиона новых случаев инфицирования. В Российской Федерации, начиная нового столетия, отмечается постепенное снижение уровня заболеваемости острым сохраняющим статус социально значимой вирусной инфекции. Вакцинация против гепатита была включена Национальный календарь профилактических прививок декабре 1997 г. Приказом Минздрава РФ...

10.51793/os.2023.26.6.001 article RU cc-by-nc-nd Лечащий врач 2023-06-23

Currently, 7 coronaviruses that cause human disease are known, 3 of which over the past 20 years have caused epidemics with a large number severe cases, high mortality rate and infection from primary focus to other countries, followed by formation epidemic foci. The last coronavirus (CVI) COVID-19 (COrona VIrus Disease 2019) arose at end December 2019 in province Hubei, China still continues. Objective research: comparative epidemiological clinical characteristics new CVI peculiarities its...

10.24110/0031-403x-2020-99-2-270-278 article EN PEDIATRIA Journal named after G N SPERANSKY 2020-03-29

Результаты многолетнего изучения герпесвирусной инфекции на кафедре инфекционных болезней у детей РНИМУ О. В. ШАМШЕВА, Ф

10.22627/2072-8107-2017-16-2-5-12 article RU cc-by CHILDREN INFECTIONS 2017-01-01

To evaluate the efficacy and safety of Ergoferon in combination with symptomatic therapy children from 6 months to years old acute respiratory infections (ARI) contemporary outpatient practice, an international, multicenter, double-blind, placebo-controlled, randomized, parallel-group clinical trial was performed. Derived by technological treatment antibodies interferon gamma, histamine, CD4, previously proved modulate its molecular targets promoting effective antiviral protection. The data...

10.1155/2021/5570178 article EN Canadian Respiratory Journal 2021-11-15

The coverage of pediatric pertussis vaccination in the Russian Federation is high, generally using a diphtheria, tetanus, and whole-cell vaccine 3-, 4.5-, 6-month primary series with booster at 18 months age. However, no registered vaccines for adults, unvaccinated adolescents adults can be major source infection infants under 3

10.1007/s40121-015-0059-9 article EN cc-by-nc Infectious Diseases and Therapy 2015-02-07

Over the past decade, calendar of preventive vaccinations in Russia has undergone significant changes, concerning, first all, inclusion new infections against which vaccination is carried out. Purpose : to analyze changes calendar. An achievement was establishment June 2018 an independent expert council Union experts field immunization and development Draft «National Strategy for Development Immunoprophylaxis Russian Federation until 2035». It expected further expand by including vaccines...

10.22627/2072-8107-2022-21-1-5-15 article EN cc-by CHILDREN INFECTIONS 2022-03-21

A retrospective analysis of the etiological structure and clinical manifestations acute intestinal infections was conducted in 8459 children hospitalized a specialized infectious disease department at Children's City Clinical Hospital No.9 Moscow, 2015—2017 based on study statistical reports for 2417 case histories aged 1 month to 18 years old. It found that with age 1—7 (58.5%) are more likely have hospitalized. The interpretation remains low level is 28.6%. leading causative agents viruses...

10.22627/2072-8107-2018-17-3-27-33 article EN cc-by CHILDREN INFECTIONS 2018-09-20

Objective: to study the clinical and laboratory manifestations of acute intestinal infections bacterial etiology in hospitalized children, depending on etiology, age, topic lesion, complications. A cohort 570 children from January October 2019 infectious wards Children's Clinical Hospital No.9 Moscow was conducted. Studies included routine methods, bacteriological analysis feces, Latex test, ELISA, PCR detect pathogens, serological reactions specific antibodies blood serum. Two groups...

10.22627/2072-8107-2019-18-4-12-18 article EN cc-by CHILDREN INFECTIONS 2019-12-06

As vaccine-induced immunity and protection following natural pertussis infection wane over time, adults adolescents may develop become transmitters to unprotected infants. In Russia, diphtheria tetanus but not pertussis-containing vaccines are registered for older children, adolescents, or adults. The reduced-antigen-content toxoid, acellular (dTpa) vaccine (Boostrix, GSK) was developed booster vaccination of children ≥4 years age, A phase III, open-label, non-randomized study performed in...

10.1080/21645515.2020.1796423 article EN cc-by Human Vaccines & Immunotherapeutics 2020-08-26

<b>Introduction</b> We assessed the epidemiologic data of influenza and other acute respiratory viral infections in children during first postpandemic season. <b>Methods</b> A retrospective analysis randomly selected case histories 2044 with ARVI. <b>Results</b> Influenza was diagnosed 40%, B 12%, ARVI 10% cases. Umifenovir (Arbidol) most frequently prescribed at prehospital hospital stages (10.2% [207/2,025] 65.2% [1,332/2,042], respectively). <b>Conclusion</b> The results suggested that...

10.1055/s-0036-1571306 article EN Journal of Pediatric Infectious Diseases 2016-01-28

In Russia, the approved morbidity statistics system is represented by International Classification of Diseases 10th revision (ICD-10). This classification provides two forms dengue fever (DF): (A90) and hemorrhagic (A91). Official on ratio DF not published in open sources this lack information about real makes it difficult to objectively assess factors that determine severity disease.compare clinical epidemiological features patients hospitalized 2009-2019 City Infectious Clinical Hospital...

10.36233/0507-4088-126 article EN cc-by Problems of Virology 2022-09-13

Purpose of the work : to conduct a clinical-epidemiological analysis intestinal infections in pediatric infectious diseases hospital and effectiveness PEWS scale. Materials methods retrospective study was conducted at Moscow City Clinical Hospital «Communarka» No. 1 disease departments from June 1, 2023, August 31, 2023. Laboratory, clinical, anamnestic data were obtained medical information system «EMIAS» laboratory (LIS) «ALISA». The analyzed 838 records children with acute respiratory...

10.22627/2072-8107-2024-23-2-17-21 article EN cc-by CHILDREN INFECTIONS 2024-06-24

The coronavirus infection is a pressing issue in modern healthcare, yet the characteristics of SARS-CoV-2 course children with comorbidities remain insufficiently studied. aim this study was to evaluate clinical form, severity, and duration virus shedding pediatric patients somatic diseases, depending on comorbid pathology. Materials Methods. A comprehensive single-center retrospective conducted, analyzing 314 medical records hospitalized infectious diseases department Russian Children’s...

10.22627/2072-8107-2024-23-4-22-28 article EN cc-by CHILDREN INFECTIONS 2024-11-16

Rotavirus infection is one of the leading causes severe diarrhea in children under five years age worldwide and contributes significantly to child mortality. The introduction rotavirus vaccination for epidemic indications into Russian National Immunization Schedule has not impacted epidemiological situation due low coverage. This article provides a review studies evaluating clinical significance context mass vaccination, as well its impact on circulation genotypes. We have analyzed data...

10.22627/2072-8107-2024-23-4-46-53 article EN cc-by CHILDREN INFECTIONS 2024-11-16

Objective. To evaluate the efficacy and safety of Raphamin® in treatment acute respiratory viral infections (ARVI) children. Patients methods. A multicenter, double-blind, placebo-controlled, randomized study was conducted an outpatient setting. Of 435 children 12-18 years old with examined, 420 patients who met eligibility criteria were included (n = 420), 1:1 into group 1 (Raphamin®, n 206) 2 (placebo, 214). Treatment 5 days follow-up up to 14 days. Time resolution symptoms infection...

10.20953/1817-7646-2024-4-54-63 article EN Voprosy praktičeskoj pediatrii 2024-01-01

Numerous literature data show the role of mycoplasma infection in development non-respiratory lesions various organs and systems, including skin. Herpesvirus infections can trigger immune-mediated inflammatory reactions skin mucous membranes — erythema multiforme exudative, Stevens-Johnson syndrome, vesicular pustular dermatosis Sneddon-Wilkinson etc. In order to study frequency nature with mycoplasmosis combined herpesvirus infection, 45 patients aged 3 15 years life were observed. A...

10.22627/2072-8107-2019-18-3-5-10 article EN cc-by CHILDREN INFECTIONS 2019-10-08

Two clinical observations of measles in sisters old 1 year 10 months and 3 years 8 have been described. Measles was severe with the development an early complication form bilateral community-acquired pneumonia pulmonary edema respiratory failure 2 degrees, which required treatment intensive care unit. At proceeded on background persistent herpetic (cytomegalovirus HHV-6) infections, at older sister pyoderma. confirmed by detection specific IgM ELISA. The were not vaccinated against had home...

10.22627/2072-8107-2019-18-2-42-48 article EN cc-by CHILDREN INFECTIONS 2019-07-03

The authors conducted an international multicenter double-blind, placebo-controlled clinical study to obtain additional data on the efficacy and safety of a 12-week course Anaferon for children prevention acute respiratory viral infections (ARVI), including influenza, in during rise seasonal morbidity (RCT Ministry Health Russian Federation: №356 dated June 29, 2017; ClinicalTrials.gov Identifier: NCT03301155). Materials methods. involved 1,036 (1 month – 6 years 11 months 29 days) two...

10.21508/1027-4065-2020-65-3-109-120 article EN Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) 2020-07-08
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