A5015744296- Pediatric health and respiratory diseases
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Human Health and Disease
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory viral infections research
- Inhalation and Respiratory Drug Delivery
- Neonatal Respiratory Health Research
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Infant Health and Development
- Chemical and Physical Studies
- Allergic Rhinitis and Sensitization
- Psoriasis: Treatment and Pathogenesis
- Child and Adolescent Health
- Rheumatoid Arthritis Research and Therapies
- Systemic Sclerosis and Related Diseases
- Respiratory Support and Mechanisms
- Pharmaceutical studies and practices
- Phonocardiography and Auscultation Techniques
- Pneumonia and Respiratory Infections
- Influenza Virus Research Studies
- Food Allergy and Anaphylaxis Research
- Herbal Medicine Research Studies
- Airway Management and Intubation Techniques
Sechenov University
2016-2025
Education and Early Childhood Development
2021
Ministry of Health of the Russian Federation
2012-2020
Moscow State University
2020
Privolzhsky Research Medical University
2016
Bronchial asthma is a heterogeneous disease that requires identification of its phenotype and personalized approach to therapy. At the same time, despite wide range therapeutic options, many patients with cannot achieve control over disease. Methodology . The target audience these clinical recommendations are general practitioners, therapists, pediatricians, allergologists-immunologists, pulmonologists, functional diagnostics doctors. Each thesis-recommendation about diagnostic procedures...
Inflammatory bowel diseases, which include Crohn’s disease and ulcerative colitis, are systemic immunoinflammatory diseases. Among the extraintestinal manifestations of these musculoskeletal lesions with seronegative spondyloarthropathies most common.The aim study was to evaluate frequency nature joint in patients inflammatory diseases observed at Sechenov Centre for Maternity Childhood period from 2017 2024.Materials Methods. The diagnoses colitis were established accordance clinical...
Background: Takayasu's arteritis (TA) is a systemic vasculitis that primarily affects the aorta and major arteries. Despite aggressive treatment with glucocorticoids (GCs) non-biological disease-modifying antirheumatic drugs (nbDMARDs), about 30% of patients experience resistance to therapy or relapse. This study aimed identify risk factors associated refractory relapse TA in pediatric patients. Methods: A retrospective, open-label, case-control was conducted 56 diagnosed between February...
Aim: Cough is an important symptom of the combined course bronchial asthma (BA) and allergic rhinitis (AR) and/or rhinosinusitis (ARS), but contribution pathology upper lower airway to formation cough in these patients cannot be considered established. The aim study was evaluate relationship intensity with indicators external respiration nasal respiratory function children adolescents a BA AR ARS. Methods: It single-center observational transverse pilot study. absence presence its were...
Psoriatic arthritis is a chronic inflammatory disease of the peripheral joints, spinal joints and entheses, occurring in 10–25% patients with psoriasis. Juvenile psoriatic classified as subtype juvenile idiopathic arthritis. Treatment challenging. One main difficulties that drugs used adult have restrictions for use pediatric practice, which limits available therapeutic options. There are few studies assessing effectiveness safety secakinumab therapy practice. Objective . To evaluate...
Inflammatory bowel diseases (IBD) Crohn's disease (CD) and ulcerative colitis (UC) are a group of idiopathic abnormal conditions with unclear etiology similar clinical courses. In addition to intestinal syndrome, these often associated extraintestinal manifestations, the most common which is involvement peripheral joints axial skeleton. The increase in incidence IBD, especially CD, childhood warrants further study this condition's features, including manifestation: joint (JI) pediatric...
On December 8, 2024, the International Council of Experts was held in Moscow to discuss methods prevention and comprehensive therapy respiratory infectious diseases children, including those with chronic diseases. The experts presented reports on several topical issues: current epidemic situation acute viral infections (ARVI) influenza, problem treatment influenza ARVI allergic conditions, hepatitis, peculiarities effect viruses immunity children. paper focused evidence base, efficacy,...
An acute cough that develops against the background of a respiratory viral infection is most common symptom in childhood. It can significantly affect quality life patients and their families. Currently, there growing interest using natural remedies to treat this type cough. To solve problem, many medicines based on natural, including herbal raw materials, be successfully used. The article demonstrates possibilities some treatment children. Ivy leaf extract (Hedera helix L.) occupies special...
Aim: The pathogenetic mechanisms and predictors of the development polyposis hypertrophy sinonasal mucosa (SM) in patients with chronic allergic airway inflammation have not been clearly established. concentration inflammatory biomarkers nasal secretions was determined children adolescents a combined course bronchial asthma (BA) rhinitis (AR) absence or presence SM. Methods: A single-centre observational cross-sectional pilot study conducted. 93 BA aged 8 to 17 years were studied. Total...
Objectives: Excess adipose tissue induces low-intensity inflammation, which is an important pathogenetic factor adversely affecting the course of bronchial asthma (BA) in overweight/obese patients. The key effector cells this inflammation are monocytes and macrophages. However, there currently no studies characterising effect body mass index (BMI) on peripheral blood monocyte levels children adolescents with BA their relationship spirometric parameters reflecting patency. aim study was to...
Juvenile psoriatic arthritis is a chronic inflammatory disease of the peripheral joints, spinal joints and entheses, which occurs in 10–25% patients with psoriasis. Studying features juvenile arthritis’s debut will increase early diagnosis help to avoid disability, socialize integrate child into society.Objective. The purpose work identify relationship between variant articular syndrome at onset provoking factor disease.Material methods. 155 an established were examined. To analyze data,...
Sarcoidosis is a multi-organ granulomatosis of unknown origin. Modern diagnostic methods allow detecting this disease at an early stage. The absence specific markers requires comprehensive approach to diagnosis based on comparison radiation, clinical, morphological and functional data. course sarcoidosis without damage the respiratory system presents significant difficulties. It extremely important understand time means starting Sarcoidosis’s treatment avoid initiation hormones cytostatics...
To evaluate the efficacy and safety of Ergoferon in combination with symptomatic therapy children from 6 months to years old acute respiratory infections (ARI) contemporary outpatient practice, an international, multicenter, double-blind, placebo-controlled, randomized, parallel-group clinical trial was performed. Derived by technological treatment antibodies interferon gamma, histamine, CD4, previously proved modulate its molecular targets promoting effective antiviral protection. The data...
Every year, a seasonal increase in the incidence of respiratory infections is registered Russian Federation, primarily among children. It significantly increases burden on outpatient pediatric service. especially important to optimize daily practice pediatricians by developing algorithms and updating treatment protocols, as well creating conducting training programs. Fever leading symptom acute viral one most common reasons for seeking help services. Leading experts field therapy pediatrics...
Allergic rhinitis (AR) and allergic rhinosinusitis (ARS) are typical upper airway pathologies (UAP) in children with bronchial asthma (BA) frequently accompanied nasal obstructive diseases (NOD). In order to establish the effect of NOD on correlations between synonasal symptoms clinical assessments control, 82 children, 9.8 [8.9; 10.7] years old, atopic BA were assessed using ACQ-5 for control level, TNSS symptoms, SNOT-20 quality life combination rhinovideoendoscopy NOD. All patients had...
Background. The study of external respiration function using spirometry in young children is associated with certain difficulties during the procedure. respiratory sound recorder a modern device which you can evaluate acoustic breathing pattern inhalation and exhalation quiet breathing. Aim. To conduct comparative analysis computer bronchophonography indicators asthma control group without pathology recorder. Materials methods. External was assessed recorder; 215 practically healthy from 1...
Cough is one of the most common symptoms in pediatric practice. It can manifest itself children as a mild cough, which has almost no effect on general condition and behavior, or, contrary, have severe debilitating character, disrupting sleep worsening child’s quality life. multifunctional problem caused by variety causes, creates certain difficulties diagnosis, especially case prolonged (subacute) chronic choosing appropriate treatment. be associated with various diseases, requires careful...
Asthma is a chronic inflammatory airway disease with bronchial hyperresponsivenes causing recurrent episodes of wheezing, dyspnea, chest tightness and cough which typically occur at nighttime or early in the morning. These are due to generalized obstruction commonly reversible spontaneously treatment. mainly diagnosed clinically should be based on patient's symptoms signs, lung function testing investigations reversibility, allergy after exclusion other diseases. The aim asthma therapy...