- Genetic and phenotypic traits in livestock
- Animal Nutrition and Physiology
- Research in Cotton Cultivation
- Livestock and Poultry Management
- MicroRNA in disease regulation
- Per- and polyfluoroalkyl substances research
- Cancer-related molecular mechanisms research
- Fluorine in Organic Chemistry
- Silkworms and Sericulture Research
- Insect Resistance and Genetics
- Nutrition, Health and Food Behavior
- Viral Infectious Diseases and Gene Expression in Insects
- Birth, Development, and Health
- Genetic Mapping and Diversity in Plants and Animals
Kangwon National University
2017-2024
Gossypol (GP), a polyphenolic compound in cottonseed, has notable effects on female reproduction and the respiratory system pigs. This study aimed to discern alterations gene expression within swine granulosa cells (GCs) when treated with two concentrations of GP (6.25 12.5 µM) for 72 h, vitro. The analysis revealed significant changes numerous genes GP-treated groups. A Gene Ontology highlighted that differentially expressed (DEGs) primarily pertained processes such as mitotic cell cycle,...
Even though the endocrine-disrupting potential of perfluorooctanoic acid (PFOA) is well known, mechanisms underlying its cellular and epigenetic toxicity at critical stage hypothalamic development are poorly understood. This why we studied effects on embryonic mouse cell line N46 (mHypoE-N46) with a hope to shed more light through which PFOA causes damage. To do that, viability, global DNA methylation, gene expression in cells exposed PFOA. As dose increased, viability decreased, while...
The present study was undertaken to find out novel single nucleotide polymorphism (SNPs) and analyze the association between SNPs of OCX-32 gene egg production traits, in four Korean native chicken breeds (Ogol, black, gray, white). Twenty-one variations (16 5 INDELs) intronic region were detected, including new 9 variants (1500T>A, 1504A>G, 1658A>G, 1668A>T, 1821A>C, 1234 del A, ins CTT, TTC, 1681 T) population (n=120). Fifteen (1346A>G, 1373G>A, 1399T>C, 1446C>G,...
Abstract Background: Gossypol (GP) is a polyphenolic compound in cottonseed. In porcine, GP affects female reproduction and the respiratory system. The aim of this study was to identify differentially expressed genes porcine granulosa cells (GCs) treated with (6.25 12.5 μM) for 72 h, vitro . Results: GP-treated groups μM), expressions number were found be significantly changed. Gene ontology analysis indicated that identified DEGs primarily related mitotic cell cycle, chromosome, centromeric...
The hepatocyte nuclear factor 4 alpha (<italic>HNF4α</italic>) gene is related to lipid transport, including abdominal fat and growth, in chickens. Interestingly, the A543G SNP within <italic>HNF4α</italic> has previously been reported be associated with body weight both broilers Korean native chickens (KNCs). However, its exact position <italic>HNF4</italic> not yet reported. This study aimed identify of additional SNPs that can used as genetic markers KNCs. A total 128 KNCs were for...
A genome-wide association study (GWAS) was performed to investigate the genetic markers associated with carcass traits of Hanwoo (Bos taurus coreanae) steer in Gangwon region Korea. (139) from were genotyped Bovine SNP50K BeadChip, and 35,769 SNPs analyzed for five specific after applying several filters. total seven quantitative trait loci detected, which four, one, 2 detected on various B. autosomal chromosomes (BTA) by respective model. The four significant backfat thickness...