A5114859833- Animal Nutrition and Physiology
- Genetic and phenotypic traits in livestock
- Gut microbiota and health
- Probiotics and Fermented Foods
- Livestock and Poultry Management
- Clostridium difficile and Clostridium perfringens research
- Agriculture, Soil, Plant Science
- Silkworms and Sericulture Research
- Genetic Mapping and Diversity in Plants and Animals
- Animal Genetics and Reproduction
- Glaucoma and retinal disorders
- Plant Reproductive Biology
- Digestive system and related health
- Mass Spectrometry Techniques and Applications
- Antifungal resistance and susceptibility
- Coccidia and coccidiosis research
- Genomics and Phylogenetic Studies
- Advanced Proteomics Techniques and Applications
- Adipose Tissue and Metabolism
- Microbial Metabolites in Food Biotechnology
- Colorectal Cancer Treatments and Studies
- Meat and Animal Product Quality
- Cancer Cells and Metastasis
- Corneal surgery and disorders
- Circular RNAs in diseases
Rural Development Administration
2022-2024
National Institute of Animal Science
2020-2024
Seoul National University
2024
Kangwon National University
2014-2019
Institute for Basic Science
2018
Daegu Gyeongbuk Institute of Science and Technology
2018
Yonsei University
2017
ObjectiveTo diagnose invasive pulmonary aspergillosis (IPA), galactomannan (GM) detection in serum or bronchoalveolar lavage fluid (BALF) is widely used. However, the utility of proximal airway GM test (from induced sputum tracheal aspirate) has not been well elucidated.MethodsIn this retrospective cohort study, we evaluated diagnostic performance diagnosis IPA including COVID-19 associated (CAPA). Between January 2022 and 2023, patients who had tested for with clinical suspicion...
ABSTRACT BACKGROUND: The effect of topical corticosteroids after excimer laser photorefractive keratectomy (PRK) remains a matter some controversy. Refractive effects may be different according to the amount myopia and timing instillation. METHODS: Two groups patients were studied: Study A consisted 215 eyes (128 patients) with PRK (mean baseline myopia, -6.53 ± 2.22 D) that received no (No Corticosteroid Group) unless significant regression or corneal haze appeared (Delayed Group), in B, we...
A main goal of cattle genomics is to identify DNA differences that account for variations in economically important traits. In this study, we performed whole-genome analyses three breeds Korea—Hanwoo, Jeju Heugu, and Korean Holstein—using the Illumina HiSeq 2000 sequencing platform. We achieved 25.5-, 29.6-, 29.5-fold coverage Hanwoo, Holstein genomes, respectively, identified a total 10.4 million single nucleotide polymorphisms (SNPs), which 54.12% were found be novel. also detected...
Health concern of dogs is the most important issue for pet owners. People who have companied long-term provide utmost cares their well-being and healthy life. Recently, it was revealed that population types gut microbiota affect metabolism immunity host. However, there little information on microbiome dogs. Hericium erinaceus (H. erinaceus; HE) one well-known medicinal mushrooms has multiple bioactive components including polyphenol, β-glucan, polysaccharides, ergothioneine, hericerin,...
The intestinal microbiome plays a crucial role in animal health and growth by interacting with the host, inhibiting pathogenic microbial colonization, regulating immunity. This study investigated dynamic changes fecal composition of piglets from birth through weaning relationship between piglet sows. Feces, skin, neonatal oral cavity, vaginal samples were collected eight sows sixty-three piglets, 16S genome sequencing was performed. results revealed that Firmicutes, Bacteroidetes,...
The present study aimed to identify causative loci and genes enriched in pathways associated with canine obesity using a genome-wide association (GWAS). GWAS was first performed candidate single-nucleotide polymorphisms (SNPs) obesity-related traits including body weight blood sugar 18 different breeds of 153 dogs. A total 10 2 SNPs were found be significantly (p < 3.74 × 10-7) sugar, respectively. None the identified trait. We subsequently followed up analysis gene-set enrichment pathway...
Small intestinal organoids are similar to actual small intestines in structure and function can be used various fields, such as nutrition, disease, toxicity research. However, the basal-out type is difficult homogenize because of diversity cell sizes types, Matrigel-based culture conditions. Contrastingly, apical-out form relatively uniform easy manipulate without Matrigel. Therefore, we sought investigate possibility replacing animal testing with bovine (Apo-IOs) by confirming mycotoxins...
This study investigates the genomic prediction accuracy for four carcass traits (Backfat thickness, Eye muscle area, Carcass weight and Marbling score) one reproduction trait (Calving Interval) using customized genotyping platform (NHanwoo1) in Korean native cattle. We use 65,351 genotyped animals after imputation with various platforms to perform accuracy. A 5-fold cross-validation method K-Means clustering was employed estimate The utilized 142,827 pedigree data associated genotypes...
가금 사육 프로그램에서 경제적으로 중요한 형질에 잠재적인 후보 유전자의 식별 및 활용은 점점 더 중요해지고 있다. Ovocalyxin-32(OCX-32) 유전자는 닭의 9번 염색체에 위치하며, 난각을 형성하는데 역할을 한다. 본 연구의 목적은 한국 재래닭의 OCX-32 유전자 내 SNP의 유전자형 결정과 산란 형질과의 연관성을 분석하기 위해 수행하였다. PCR-RFLP 방법을 통해 오골계 46수, 백색 회색 43수, 흑색 46수를 포함한 총 181수의 재래닭 암컷 4종의 SNP을 분석하였다. 형질은 시산일령, 시산난중, 산란율, 난중의 4가지 항목을 포함하여 측정하였다. c.494A>C SNP은 오골계의 산란율과 유의적인 차이를 나타냈으며(p<0.001), 재래닭에서는 난중과 상관관계가 있었다(p<0.05). c.267T>G 연관성이 나타났다(p<0.05). 하지만 회색과 나타나지 않았다. 연구 결과, 산란형질을 선발하는 마커로 사용되기까지 추후 많은 개체군을 통한 연구가...
GHSR 유전자 변이에 대한 선행연구는 몇몇의 변이가 닭의 성장형질에 영향을 미칠 수 있으며, 유전자마커로써 활용될 있음을 보고하였다. 하지만 한국재래계를 대상으로 하는 유전연구는 매우 미흡하고, 외래계 대상의 유전자마커의 도입에는 검증실험이 선 요구된다. 따라서 본 논문은 유전자의 성장형질과의 연관성을 확인하며, 한국재래계에 적용할 있는 유전자마커를 제시하고자 하였다. 국립축산과학원에서 사육 중인 6계통의 한국재래계 220수를 공시재료로 하여 체중과의 연관성이 보고된 바 c.739+726SNP 유전자형을 PCR-RFLP 방법을 통하여 분석하였다. 이후 집단 내에서 30수를 선발하여 염기서열 분석을 수행함으로써 한국재래계내 변이를 확인하였다. c.739+726SNP을 포함하여 통해 파악된 변이와 한국재래계의 경제형질과의 연관성 분석에는 SPSS version 22.0을 이용하였다. c.739+726SNP은 전체계 군(n=220)에서 150일령 체중과 270일령 확인할...
The present study was undertaken to find out novel single nucleotide polymorphism (SNPs) and analyze the association between SNPs of OCX-32 gene egg production traits, in four Korean native chicken breeds (Ogol, black, gray, white). Twenty-one variations (16 5 INDELs) intronic region were detected, including new 9 variants (1500T>A, 1504A>G, 1658A>G, 1668A>T, 1821A>C, 1234 del A, ins CTT, TTC, 1681 T) population (n=120). Fifteen (1346A>G, 1373G>A, 1399T>C, 1446C>G,...
Objective: The study of Hanwoo (Korean native cattle) has mainly been focused on meat quality and productivity. Recently the field microbiome research increased dramatically. However, information in is still insufficient, especially relationship between vagina feces. Therefore, purpose this to examine microbial community characteristics by analyzing 16S rRNA sequencing data feces, as well confirm difference correlation vaginal fecal microorganisms. As a result, goal investigate if can be...
Gut microbiomes are well recognized to serve a variety of roles in health and disease, even though their functions not yet completely understood. Previous studies have demonstrated that the juvenile adult dogs significantly different compositions characteristics. However, there is still scarcity basic microbiome research dogs. In this study, we aimed advance our understanding by confirming difference fecal between young analyzing feces 4-month 16-month-old Jindo dogs, domestic Korean breed....
Abstract The swine gut microbiota is populated by large and diverse bacterial community that play an essential role in pig intestinal development. Therefore, it important to characterize the composition of determine which factor shape microbiota. Our objective was at different growth stages using 16S rRNA gene high-throughput sequencing data from gastrointestinal (GI) samples. First, samples were collected GI tract sections (duodenum, jejunum, ileum, cecum, colon, fecal) a total 36 piglets...