Jelena Spasic

ORCID: 0000-0002-1607-857X
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About
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Research Areas
  • Enzyme Catalysis and Immobilization
  • Microbial Natural Products and Biosynthesis
  • Microbial Metabolism and Applications
  • Photosynthetic Processes and Mechanisms
  • Algal biology and biofuel production
  • Enzyme-mediated dye degradation
  • Biochemical Acid Research Studies
  • Biochemical and biochemical processes
  • Microplastics and Plastic Pollution
  • Chemical Reaction Mechanisms
  • Plant biochemistry and biosynthesis
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Synthesis and Reactions of Organic Compounds
  • Microbial Fuel Cells and Bioremediation
  • Synthetic Organic Chemistry Methods
  • Macrophage Migration Inhibitory Factor
  • biodegradable polymer synthesis and properties
  • Sulfur-Based Synthesis Techniques
  • Microbial Community Ecology and Physiology
  • Radical Photochemical Reactions
  • Biopolymer Synthesis and Applications

Graz University of Technology
2021-2025

Institute of Molecular Biotechnology
2021-2025

Universidade do Porto
2021-2023

i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2021-2023

University of Belgrade
2015-2021

BioTechMed-Graz
2021

Institute of Molecular Genetics and Genetic Engineering
2019

Abstract The recent increase of interest in photocatalysis spread to biocatalysis and triggered a rush for the development light‐dependent enzyme‐mediated or enzyme‐coupled processes. After several years intense research on photobiocatalysis, it is time evaluate state field structured manner. In this Perspective, we suggest group photobiocatalysis into distinct disciplines provide principal guidelines standards reporting photobiocatalytic results as well advice performing reactions. Overall,...

10.1002/cptc.202200325 article EN cc-by ChemPhotoChem 2023-05-02

The α‐methylene‐γ‐butyrolactone tulipalin A, a defense compound found in tulips, can polymerize via addition at the vinyl group or ring‐opening polymerization, making it highly promising monomer for bio‐based polymers. Since biosynthesis of A plants remains elusive, we propose an alternative pathway its synthesis starting from terpenoid intermediate isoprenyl acetate. While fungal unspecific peroxygenases showed preference unwanted epoxidation exo‐olefin group, bacterial alkane...

10.1002/anie.202503464 article EN other-oa Angewandte Chemie International Edition 2025-03-21

The α‐methylene‐γ‐butyrolactone tulipalin A, a defense compound found in tulips, can polymerize via addition at the vinyl group or ring‐opening polymerization, making it highly promising monomer for bio‐based polymers. Since biosynthesis of A plants remains elusive, we propose an alternative pathway its synthesis starting from terpenoid intermediate isoprenyl acetate. While fungal unspecific peroxygenases showed preference unwanted epoxidation exo‐olefin group, bacterial alkane...

10.1002/ange.202503464 article EN Angewandte Chemie 2025-03-21

Cyanobacteria have the capacity to use photosynthesis fuel their metabolism, which makes them highly promising production systems for sustainable of chemicals. Yet, dependency on visible light limits cell-density, is a challenge scale-up. Here, it was shown with example light-dependent biotransformation that internal illumination in bubble column reactor equipped wireless emitters (WLEs) could overcome this limitation. Cells cyanobacterium Synechocystis sp. PCC 6803 expressing gene...

10.1002/cssc.202100832 article EN cc-by ChemSusChem 2021-06-17

Three Streptomyces sp. strains with a multitude of target enzymatic activities confirmed by functional screening, namely BV129, BV286 and BV333, were subjected to genome sequencing aiming at the annotation genes interest, in-depth bioinformatics characterization expression biocatalysts. A whole-genome shotgun followed de novo assembly was performed revealing genomes 6.4, 9.4 7.3 Mbp, respectively. Functional proteins interest resulted in between 2047 2763 putative targets. Among various that...

10.3390/catal11080919 article EN Catalysts 2021-07-29

Biocatalytic potential of Streptomyces strains isolated from the rhizosphere plants and mycorrhizosphere fungi has been investigated. A total 118 isolates were selected functionally screened for 10 different biotechnologically important enzymatic activities: hydrolase (cellulase, cutinase, gelatinase, lipase, protease, polyhydroxyalkanoate (PHA) depolymerase), phenol oxidase peroxidase (laccase, tyrosinase, lignin peroxidase), aminotransferase. Out tested spp., 90% showed at least one...

10.1002/bab.1664 article EN Biotechnology and Applied Biochemistry 2018-05-24

Abstract The α-methylene-γ-butyrolactone tulipalin A, naturally found in tulips can polymerize via addition at the vinyl group or ring-opening polymerization, making it a highly promising monomer for biobased polymers. As A biosynthesis plants remains elusive, we propose pathway its synthesis starting from metabolic intermediate isoprenol. For this, terminal hydroxylation of α-methylene substrate isoprenyl acetate is decisive step. While panel fungal unspecific peroxygenases showed...

10.1101/2024.07.04.601532 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-07-08

Michael addition of aldehydes to nitroolefins is an effective method obtain useful chiral ?-nitroaldehydes. ?-Nitroaldehydes are precursors for ?-aminobytiric acid analogues which have numerous pharmacological activities and used treatment neurological disorders. A whole-cell system based on recombinantly expressed 4-oxalocrotonate tautomerase (4-OT) has been developed shown be biocatalyst branched ?-nitrostyrenes. The aim this study was investigate the influence substitution N-terminal...

10.2298/jsc160222053l article EN Journal of the Serbian Chemical Society 2016-01-01
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