A5016992470- Biochemical Analysis and Sensing Techniques
- Olfactory and Sensory Function Studies
- Fibroblast Growth Factor Research
- Autophagy in Disease and Therapy
- Heme Oxygenase-1 and Carbon Monoxide
- Macrophage Migration Inhibitory Factor
- Adipose Tissue and Metabolism
- Nitric Oxide and Endothelin Effects
- Receptor Mechanisms and Signaling
- Neurobiology and Insect Physiology Research
Hebei North University
2024
Shandong University
2020-2022
To investigate the role of Parkin overexpression-induecd mitophagy in alleviating acute lung injury exertional heat stroke(EHS) rats. Eighty SD rats were divided into four groups: Control group (CON group), overexpression + stroke (EHS and group). Adeno-associated virus carrying gene was intravenously injected to overexpress tissue. An rat model established, survival curves plotted. Lung Micro-CT performed, coefficient pulmonary microvascular permeability measured. Enzyme-linked...
Along with functionally intact insulin, diabetes-associated insulin peptides are secreted by β cells(1-3). By screening the expression and functional characterization of olfactory receptors in pancreatic islets, we identified Olfr109 as receptor to detect peptides. Engagement one peptide, insB:9-23, diminished secretion through Gi-cAMP signalling promoted macrophage proliferation. Remarkably, deficiency alleviated intra-islet inflammatory responses improved glucose homeostasis Akita- HFD-fed...