A5082179335- Nail Diseases and Treatments
- Dermatology and Skin Diseases
- Oral Health Pathology and Treatment
- Dermatologic Treatments and Research
- Autoimmune Bullous Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Hair Growth and Disorders
- melanin and skin pigmentation
- Skin Protection and Aging
- Systemic Sclerosis and Related Diseases
- Dermatological and Skeletal Disorders
- Acne and Rosacea Treatments and Effects
- Drug-Induced Adverse Reactions
- Cytomegalovirus and herpesvirus research
- Allergic Rhinitis and Sensitization
- Fungal Infections and Studies
- Psoriasis: Treatment and Pathogenesis
- Dermatological diseases and infestations
- Textile materials and evaluations
- Retinoids in leukemia and cellular processes
- Urticaria and Related Conditions
- Skin Diseases and Diabetes
- Pharmacovigilance and Adverse Drug Reactions
- Genital Health and Disease
- RNA regulation and disease
Ankara Bilkent City Hospital
2024-2025
Memorial Ankara Hospital
2021-2024
Bilkent University
2024
Ankara Atatürk Eğitim ve Araştırma Hastanesi
2013-2019
Ministry of Health
2016-2018
Rosacea is the chronic inflammatory disease of facial skin. Although its aetiology not clear yet, processes triggered by oxidative stress and oxidation lipids have been suggested to play a role. While studies on relationship between inflammation are ongoing, thiol metabolism role in also begun be investigated. Thiols among key molecules protein organism they firstly consumed antioxidants case stress. regulate intracellular redox protect keratinocytes against results alterations stratum...
Seborrheic dermatitis (SD) is a common, chronic inflammatory disease with relapses and remissions.So we planned to investigate the relationship between SD metabolic syndrome (Mets).54 patients over 18 years of age without known diabetes mellitus, hypertension, coronary artery who were clinically diagnosed in our clinic 47 healthy controls included study. Body mass index (BMI) was calculated all participants. Complete blood count, fasting sugar (FBG), triglyceride (TG), total cholesterol,...
Vitiligo is an acquired depigmentation disorder, and oxidative stress suggested to have a major role in its aetiopathogenesis. To assess whether has greater generalized than localized vitiligo. We assessed 31 patients with active vitiligo (17 localized, 14 generalized) 38 healthy controls. Serum total oxidant status (TOS), antioxidant (TAS) index (OSI) were determined. Patients had significantly lower TAS higher TOS OSI values Both associated values, compared controls, all three did not...
Thiol-disulphide balance plays a major role in health and diseases. This may be disrupted by various We aimed to determine status of the effect thiol-disulphide urticaria.We investigate patients with acute urticaria (AUP) chronic spontaneous (CSU).Study included 53 AUP 47 healthy controls plus 57 (CSUP) controls. Levels native thiols, disulphides total thiols were evaluated plasma using new automated spectrophotometric method. Ratios disulphides/total disulphides/native thiols/total...
Recurrent aphthous stomatitis (RAS) is a chronic relapsing inflammatory disorder of the oral mucosa with unknown etiology. Oxidative stress (OS) suggested to play main role in etiopathogenesis RAS.In this study, we hypothesize that systemic OS present patients RAS.Forty-four active RAS lesions and 38 healthy controls were being included study. Serum total oxidant status (TOS), antioxidant (TAS), oxidative index (OSI), paraoxonase 1 arylesterase (ARES) activity determined.RAS had...
According to studies conducted in outpatients, it is estimated that 2.5% of children who are treated with a drug will experience cutaneous adverse reaction (CADR).To analyze the CADR reports involving pediatric patients recorded by three different university hospitals for describing common, serious, and interesting eruption patterns.For this purpose, patients' data from universities were reviewed retrospectively. Diagnosis was based on history, clinical findings laboratory test results. The...
Seborrheic dermatitis is a common papulosquamous skin disease with unknown pathogenesis. The aim of our study was to determine the serum level 25-hydroxy vitamin D in patients seborrheic SD.A total 53 and 60 healthy controls were included study. Serum D, calcium, phosphorus, parathormone levels measured patient control groups, comparison made between two groups regarding these parameters.Severe deficiency more frequent among dermatitisSD compared (52.8 vs. 25.8%, p=0.003). In severe...
Pityriasis rosea (PR) is a common, acute, self-limiting inflammatory skin disease. It can easily be recognized with its typical clinical presentation. However, unusual clinic presentations cause difficulty in diagnosis. Up to now, not many atypical forms are reported.To determine the characteristics of patients pityriasis rosea.A total 27 cases, diagnosed as PR by and/or histopathological examination and applied outpatient dermatology department between years 2007 2015 were analyzed...
Introduction: Morphea localized scleroderma (LS) is a rare skin disease with unknown pathogenesis, which causes sclerosis of the dermis and subcutaneous tissue. Objectives: It was aimed to compare characteristics patients pediatric adult-onset morphea. Methods: A retrospective analysis performed on records 183 adult morphea patients. The demographics, clinical laboratory characteristics, treatment options were recorded. Adult over age 18 divided into two groups according onset compared....
Hyperhidrosis is a condition where the amount of sweat released to skin surface increases due over-active eccrine glands. causes considerable psychosocial distress in affected people. It affects quality life and leads social anxiety disorders.No study has been conducted our country investigate epidemiological, clinical, laboratory data patients with hyperhidrosis. In this study, we aimed retrospectively clinical demographic characteristics, sweating findings treated for hyperhidrosis at...
Venous hypertension causes many different cutaneous findings such as varicosities, telangiectasia, edema, and pigmentation, dermatitis, venous ulcers on the skin.This study aims to investigate signs symptoms of chronic insufficiency (CVI) examine their contribution early diagnosis.A total 150 patients were included in who applied dermatology outpatient clinic diagnosed with skin disease related CVI or had findings. Patient's age, gender, complaints, occupation, additional diseases, drug...
Tinea versicolor is a superficial fungal infection caused by Malassezia spp. member of the normal human skin flora. It becomes pathogen transforming from yeast form to mycelium form. The oxidant/antioxidant homeostasis may be responsible for this. Thiol/disulphide new marker indicating oxidative stress. This affected in many illnesses.To investigate thiol/disulphide patients with tinea versicolor.Forty-two (median age: 36 years, min.-max.: 19-58) and healthy controls 32 18-60) were included...
Nails which help the free movement of fingers, protects them from traumas, to be kept small objects, used for itching and also important cosmetic appearance [1]. Nail disorders may cause sociopsychological problems as this will adversely affect quality life. in childhood are mainly similar adults some physiological changes occur by time disappear over years. a sign systemic disease such congenital hereditary diseases, infections dermatoses [2]. Distribution frequency nail disordres differs...
Background: Thiols are antioxidant, organic compounds containing sulfhydryl group on their active sites.They have important roles preventing oxidative stress.The thiol disulfide homeostasis has a vital importance in organism.Thiol imbalance is an early indicator of stress.Alopecia areata autoimmune skin disorder characterized with scar-free hair loss.Its pathogenesis still unclear.Thiol these patients not been studied at all.Objective: To evaluate the alopecia and healthy controls.Methods:...
Objective: The study was performed to determine the prevalence and demographic characteristics of patients, who were diagnosed with superficial fungal infection at dermatology department two centers, compare their epidemiologic data those reported in literature. Material Method: Files 20716 children, between 0 16 years age, presented Dermatology Outpatient Clinic 2011 2015, investigated retrospectively. Of these, 518 infection, evaluated respect gender, presence systemic disease...
Telogen effluvium (TE) is the most common reason for hair loss in humans. Although exact etiopathogenesis of TE has not been revealed clearly and completely, multifactorial etiologies are to be blamed. In recent years, since oxidative stress (OS) shown play an important role so many diseases, effects OS on several skin diseases researched analyzed. Thiols antioxidant components that include sulfur group, balance thiol-disulfide formation prevention OS. This destroyed its effect understood...
Amaç: Ankara'da bir çocuk hastanesi dermatoloji bölümüne başvuran hastalardaki deri hastalıkları sıklığının belirlenmesi
Background: To determine the incidence and demographic characteristics of skin diseases presenting with hyperpigmentation in children applying to dermatology department.Methods: A total 2815 between ages 0 16 who applied clinic complaints disorders were evaluated.The age, gender, socioeconomic status, place residence abnormal pigmentation lesions investigated.Results: during study period.Of these patients 1491 female (53%) 1324 male (47%).Of 266 (9.4%) diagnosed hyperpigmention.The causes...
Objective: Lichenoid drug reactions (LDR) are a rarely known type of reaction that resembles lichen planus. The exact etiology LDR is not but it thought to be caused by the triggering all kinds chemical substances. In this study; we aimed investigate clinical and demographic characteristics patients who were diagnosed with LDR. Material Method: files 56 followed in our outpatient clinic among 2011 - 2016 have been reviewed retrospectively. characteristics, drugs considered cause reaction,...
Localized scleroderma is a rare inflammatory skin disease that causes sclerosis in the dermis and subcutaneous tissue. Oxidative stress may play role etiology or be responsible for chronicity progression of disease.
Objective: Our aim was to determine the frequency and demographic characteristics of patients presenting at department pediatric dermatology with complaints mouth lip lesions compare their epidemiological data literature in this study. Material Methods: Of 3000 children aged between 0 16 who presented outpatients 2011 January December, had been brought sores were retrospectively assessed terms age, gender, socio-economic level (SEL), medicine use, disease history, systemic presence genetic...