A5078813097- Autoimmune Bullous Skin Diseases
- Acne and Rosacea Treatments and Effects
- melanin and skin pigmentation
- Oral Health Pathology and Treatment
- Dermatological and COVID-19 studies
- Urticaria and Related Conditions
- Nail Diseases and Treatments
- Cutaneous lymphoproliferative disorders research
- Hair Growth and Disorders
- Ocular Diseases and Behçet’s Syndrome
- Mast cells and histamine
- Autoimmune and Inflammatory Disorders
- Retinoids in leukemia and cellular processes
- Dermatology and Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Skin Protection and Aging
- Ottoman and Turkish Studies
- Drug-Induced Adverse Reactions
- Hidradenitis Suppurativa and Treatments
- Dermatological and Skeletal Disorders
- Cardiovascular Disease and Adiposity
- Dermatologic Treatments and Research
- Nonmelanoma Skin Cancer Studies
- Bee Products Chemical Analysis
- Skin and Cellular Biology Research
Ankara Yıldırım Beyazıt University
2016-2025
Ankara Bilkent City Hospital
2024-2025
New York University
2024
Memorial Ankara Hospital
2021-2023
City Hospital
2023
University of Milan
2023
University of California, Davis
2023
Aarhus University Hospital
2023
Women's College Hospital
2023
University of Toronto
2023
This study investigated the serum 25-hydroxyvitamin D levels of patients with Behcet's Disease.Thirty-two Disease and 31 matched healthy controls were enrolled in this study. The erythrocyte sedimentation rate (ESR) C-reactive protein (CRP), D, calcium (Ca), phosphate (P), total alkaline phosphatase (ALP) measured both groups.There no significant differences between two groups regarding demographic data. 13.76 (range: 4.00-35.79) 18.97 12.05-36.94) ng/ml, respectively. In Disease, values...
Rosacea is the chronic inflammatory disease of facial skin. Although its aetiology not clear yet, processes triggered by oxidative stress and oxidation lipids have been suggested to play a role. While studies on relationship between inflammation are ongoing, thiol metabolism role in also begun be investigated. Thiols among key molecules protein organism they firstly consumed antioxidants case stress. regulate intracellular redox protect keratinocytes against results alterations stratum...
To compare the corneal topographic parameters and ocular surface of rosacea (OR) patients across skin subtypes disease healthy controls. This prospective study included 180 eyes 90 OR 60 30 Among patients, had phymatous (60 eyes), erythematotelangiectatic eyes) papulopustular types eyes). We measured mean keratometry (Kmean), maximum (Kmax), thinnest thickness (TCT), central (CCT) volume (CV) with a topography device (Sirius, Italy). Additionally, we tear-film breakup time (TBUT), Meiboscore...
The aim of this study is to measure and compare the dynamic thiol/disulphide homeostasis patients with basal cell carcinoma healthy subjects a newly developed original method.Thirty four attending our outpatient clinic clinically histopathologically diagnosed as nodular carcinoma, age gender matched 30 individuals have been involved in study. Thiol/disulphide tests measured novel automatic spectrophotometric method results compared statistically.Serum native thiol disulphide levels patient...
Recently, increased reactive oxygen species (ROS), reduced antioxidant capacity, and oxidative stress have been suggested in the pathogenesis of psoriasis. The aim this study to evaluate thiol/disulfide homeostasis patients with psoriasis.Ninety psoriasis who did not receive any systemic treatment last six months were included study. Seventy-six age gender-matched healthy volunteers served as control group. Thiol/disulfide was measured venous blood samples obtained from patient groups.Native...
Thiol-disulphide balance plays a major role in health and diseases. This may be disrupted by various We aimed to determine status of the effect thiol-disulphide urticaria.We investigate patients with acute urticaria (AUP) chronic spontaneous (CSU).Study included 53 AUP 47 healthy controls plus 57 (CSUP) controls. Levels native thiols, disulphides total thiols were evaluated plasma using new automated spectrophotometric method. Ratios disulphides/total disulphides/native thiols/total...
To investigate oxidative stress markers in tears and serum of patients with ocular rosacea to examine their association both surface parameters cutaneous subtypes.This prospective study includes involvement healthy controls. We performed ophthalmological examination all participants collected tear breakup time (TBUT), Schirmer, Meibomian gland dysfunction (MGD) Ocular Surface Disease Index (OSDI) scores. quantified the total antioxidant status (TAS), oxidant (TOS), arylesterase (ARE) levels...
Objective: Dermatomycosis is an infection with fungi related to the skin: glabrous skin, hair and/or nails.Oral treatment of fungal infections in dermatology has become a preferred modality for management these very common conditions.Although there are increasing numbers antifungals available dermatophytes, some cases and relapses have been unresponsive treatment.The determination fungus in-vitro antifungal susceptibility reported be important ability eradicate dermatophytes.It necessary...
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening acute mucocutaneous disorders usually triggered by drugs. In this study, we aimed to evaluate the factors affecting mortality in patients with SJS-TEN. Our study is a retrospective cohort analyzing data collected from total of 12 tertiary care centers between April 2012 2022. The included 59 males 107 females, 166 patients, an average age 50.91 ± 21.25 years. Disease classification was TEN 50% cases, SJS...
Abstract Background Androgenetic alopecia (AGA) is the most common type of hair loss and affects approximately 50% male population. Aims In present study, to investigate microinflammation, perifollicular fibrosis, oxidative stress in AGA cases, some serum biomarker levels were measured evaluated. Patients/Methods Serum samples drawn from patients (n = 58) control 30) groups referring Atatürk Training Investigation Hospital Dermatology Outpatient clinic. samples, NF‐κB, TNF‐α, TGF‐β1,...
Abstract Confluent and reticulated papillomatosis (CRP) is a relatively rare disorder of unknown origin, mostly affecting young female adults. We here present the case 21‐year‐old male patient with confluent papillomatosis. Skin examination revealed brownish, verrucous, hyperkeratotic, 2 to 5 mm papules, which formed patches plaques reticulate network on interscapular area. The was initially treated ketoconazole cream for two weeks without improvement. disease can be rather persistent...
Lichen planus (LP) is a mucocutaneous inflammatory disease. Inflammation plays major role in the progression of atherosclerosis. Epicardial fat tissue (EFT) has been shown to produce and secrete various proatherogenic proinflammatory hormones cytokines. The aim this study was assess EFT patients with lichen planus. Fifty-four LP 50 controls were enrolled study. diagnosed according World Health Organization criteria. measured on free wall right ventricle parasternal long-axis view, as...
Pityriasis rosea (PR) is a common, acute, self-limiting inflammatory skin disease. It can easily be recognized with its typical clinical presentation. However, unusual clinic presentations cause difficulty in diagnosis. Up to now, not many atypical forms are reported.To determine the characteristics of patients pityriasis rosea.A total 27 cases, diagnosed as PR by and/or histopathological examination and applied outpatient dermatology department between years 2007 2015 were analyzed...
Abstract Folliculitis decalvans is a rare and chronic progressive hair disorder leading to scarring alopecia atrophy. Its etiology still unclear. It starts with areas of perifollicular erythema, follicular papules pustules spread peripherally, leaving central scarred patches alopecia. We report 27‐year‐old man who presented folliculitis involving the scalp, face, nape, beard. There were pustules, crusts, on scalp
Objective Lichen planus ( LP ) is an autoimmune inflammatory disease of the mucocutaneous tissue, whose exact pathological course remains unclear. Abnormal thiol/disulfide homeostasis has been postulated to be responsible for a number diseases predominated by chronic inflammation. To able contribute complicated and unclear pathogenesis , we aimed investigate dynamic in patients with using original automated method developed Erel Neselioglu this study. Methods The study group consisted 81...
To compare the choroidal thickness (CT) and vascularity index (CVI) values in ocular rosacea (OR) patients across skin subtypes of disease healthy controls.
The purpose of our study is to find out in which weeks and cumulative doses the side effects emerge whether or not there a significant variance between observed period emergent patients taking daily below above 0.5 mg/kg.Patients were started treatment with 0.25-1 mg/kg isotretinoin, form was given mark probable occurred called for weekly follow-up first 2 months.The median complaints emerged such as chellitis, dry face facial erythema, photobia nyctalopia less than 4 weeks. When taken are...
Vitiligo is a depigmenting cutaneous disorder with complex pathogenesis. Thiol compounds are well-known organic structures that play major role in melanogenesis.The aim of this study was to determine the association between plasma thiol level and disease severity patients nonsegmental vitiligo.A total 73 vitiligo (57 generalized 16 localized type) age- sex-matched 69 healthy controls were enrolled study. Plasma levels native thiols, disulfides, thiols measured by novel automated assay....