Nazli Mert-Ozupek

ORCID: 0000-0002-1627-1548
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About
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Research Areas
  • Seaweed-derived Bioactive Compounds
  • Advanced Chemical Sensor Technologies
  • Salivary Gland Disorders and Functions
  • Metabolomics and Mass Spectrometry Studies
  • Marine Sponges and Natural Products
  • Echinoderm biology and ecology
  • MicroRNA in disease regulation
  • Circular RNAs in diseases
  • Protein Hydrolysis and Bioactive Peptides
  • Colorectal and Anal Carcinomas
  • Curcumin's Biomedical Applications
  • Cancer, Hypoxia, and Metabolism
  • Aquaculture Nutrition and Growth
  • Marine Biology and Environmental Chemistry
  • Geological Studies and Exploration
  • Marine and coastal plant biology
  • Nutritional Studies and Diet
  • Colorectal Cancer Treatments and Studies
  • Algal biology and biofuel production
  • Genetic factors in colorectal cancer
  • Moringa oleifera research and applications
  • Biochemical Analysis and Sensing Techniques
  • Analytical Chemistry and Chromatography
  • Metabolism, Diabetes, and Cancer
  • Cancer-related molecular mechanisms research

Dokuz Eylül University
2017-2024

Ege University
2024

Tarsus University
2024

Izmir Institute of Technology
2024

Halophila stipulacea is a well-known invasive marine sea grass in the Mediterranean Sea. Having been introduced into Sea via Suez Channel, it considered Lessepsian migrant. Although, unlike other seaweeds, has not demonstrated serious negative impacts on indigenous species, does have remarkable properties. The present in-silico study reveals biotechnological features of H. by showing bioactive peptides from its rubisc/o protein. These are such as antioxidant and hypolipideamic activities,...

10.3390/cells8060557 article EN cc-by Cells 2019-06-07

The aim of the study was in-silico drug-likeness analysis, absorption, distribution, metabolism, and excretion (ADME) properties, molecular docking studies anthocyanins as natural anticancer compounds against acting receptor-like kinase 5 (ALK5) receptor. Transforming growth factor-β (TGF-β) plays an essential role in various cellular processes. Increased expression TGF-β its receptor TGFβR-I (i.e. ALK5) have been associated with poor prognosis cancer patients.The activity performed using...

10.1097/cad.0000000000001297 article EN Anti-Cancer Drugs 2022-03-23

Biological invasion is the successful spread and establishment of a species in novel environment that adversely affects biodiversity, ecology, economy. Both invasive non-invasive Caulerpa genus secrete more than thirty different secondary metabolites. Caulerpin one most common metabolites Caulerpa. In this study, caulerpin found cylindracea lentillifera extracts were analyzed, quantified, compared using high-performance thin layer chromatography (HPTLC) for first time. The anticancer...

10.3390/md20120757 article EN cc-by Marine Drugs 2022-11-30

Caulerpa spp. secrete more than thirty different bioactive chemicals which have already been used in cancer treatment research since they play a pivotal role metabolism. Colorectal is one of the most common types, thus using novel and effective for colorectal crucial. In cheminformatics pipeline this study, ADME-Tox drug-likeness tests were performed filtering secondary metabolites The ligands selected from ADME test silico molecular docking studies against enzymes oxidative branch pentose...

10.3389/fchem.2022.1046313 article EN cc-by Frontiers in Chemistry 2022-12-06

<title>Abstract</title> In recent years, numerous metabolomics experiments on lung cancer have not only identified novel biomarkers for early diagnosis, but also investigated the altered metabolic pathways to enhance our understanding of its pathogenesis. Thin-film microextraction (TFME) is a non-invasive, cost-effective, and selective analytical technique rapid identification metabolite in clinical samples has significant potential be used this field. This study aimed investigate role...

10.21203/rs.3.rs-4362652/v1 preprint EN cc-by Research Square (Research Square) 2024-05-31

The incidence of cancer has exhibited an increasing trend in recent years because many reasons such as environmental and nutritional factors. There is a great need for the development new natural molecules with lower side effects therapy cancer. It was aimed to evaluate antiproliferative effect semi-purified triterpene glycosides Holothuria poli on different human cell lines. body walls H. main sources saponins were used saponin content extract characterized by MALDI-TOF/MS....

10.1080/01635581.2021.1952630 article EN Nutrition and Cancer 2021-08-28
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