A5100411400- Functional Brain Connectivity Studies
- Child Development and Digital Technology
- Autism Spectrum Disorder Research
- Advanced Neuroimaging Techniques and Applications
- Brain Tumor Detection and Classification
- Regulation of Appetite and Obesity
- Behavioral and Psychological Studies
- S100 Proteins and Annexins
- Receptor Mechanisms and Signaling
- Neural dynamics and brain function
- Advanced MRI Techniques and Applications
- Endoplasmic Reticulum Stress and Disease
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Health and Well-being Studies
- Pancreatic function and diabetes
- Child Nutrition and Feeding Issues
- Neuroinflammation and Neurodegeneration Mechanisms
- Assistive Technology in Communication and Mobility
Zhejiang University
2023
Hangzhou Seventh Peoples Hospital
2023
Xi'an Medical University
2022
Fujian University of Traditional Chinese Medicine
2022
Peking University
2022
Laboratoire d’Imagerie Biomédicale
2015
Imaging Center
2015
Aberrant resting-state functional connectivity (FC) of anterior cingulate cortex (ACC) has been implicated in the pathophysiology schizophrenia and bipolar disorder (BP). This study investigated subregional FC ACC across psychotic (PBP) nonpsychotic BP (NPBP) relationship between brain alterations clinical manifestations. A total 174 first-episode medication-naive patients with (FES), 80 PBP, 77 NPBP 173 demographically matched healthy controls (HCs) underwent magnetic resonance imaging....
To investigate the effect of ghrelin, a brain-gut peptide hormone, on high glucose-induced retinal angiogenesis in vitro and explore its association with endoplasmic reticulum (ER) stress.Human microvascular endothelial cells (HRMECs) were first divided into control high-glucose groups, mRNA protein expression levels receptor for ghrelin [growth hormone secretin 1a, (GHSR-1a)] determined. HRMECs then treated glucose alone or combination siGHSR-1a, cell viability, migration, tube formation ER...
Synapse loss and memory decline are the primary features of neurodegenerative dementia. However, molecular underpinnings that drive remain largely unknown. Here, we report FAM69C is a kinase critically involved in Biochemical analyses uncover serine/threonine kinase. We generate Fam69c knockout mice show by single-cell RNA sequencing deficiency drives cell-type-specific transcriptional changes relevant to synapse dysfunction. Electrophysiological, morphological, behavioral experiments...
Play is an indispensable and meaningful activity in children's daily life. Research has shown that autistic children often exhibit differences play development. The core traits of autism, such as distinct patterns social interaction communication, focused interests, repetitive behaviors, frequently manifest their play. Therefore, may serve insightful measure these differences. Unlike previous studies focusing on behaviors only, we explored other associated with autism during free play,...
Abstract Background The COVID-19 pandemic has caused an unprecedented need for accessible health care services and significantly accelerated the development processes of telehealth tools autism spectrum disorder (ASD) early screening diagnosis. This study aimed to examine feasibility utility a time-efficient tool combining structured snack time assessment activity novel behaviour coding scheme identifying ASD. Methods A total 134 1–6-year-old individuals with ASD (age in months: mean = 51.3,...