A5053273777- Osteoarthritis Treatment and Mechanisms
- Human Health and Disease
- Pain Mechanisms and Treatments
- Musculoskeletal pain and rehabilitation
- Inflammatory mediators and NSAID effects
- Healthcare Systems and Public Health
- Neurological Disorders and Treatments
- Acupuncture Treatment Research Studies
- Myofascial pain diagnosis and treatment
- Neurological Disease Mechanisms and Treatments
- Healthcare and Venom Research
- Spine and Intervertebral Disc Pathology
- Medical and Biological Sciences
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Medicinal plant effects and applications
- Pain Management and Treatment
- Complementary and Alternative Medicine Studies
- Medicinal Plants and Bioactive Compounds
- Pain Management and Placebo Effect
- Therapeutic Uses of Natural Elements
- Long-Term Effects of COVID-19
- Bach Studies and Logistics Development
- Natural Products and Biological Research
- Language, Communication, and Linguistic Studies
- Medical and Biological Ozone Research
Sechenov University
2017-2025
AIM: To analyze the mechanisms and effectiveness of a rehabilitation program combining psychocorrection transcutaneous electrical stimulation in individuals with post-stress disorders engaged high-risk professions. MATERIALS AND METHODS: The study included 120 men repeated participation combat operations, demonstrating high levels stress. Within this group, two categories were identified (each comprising 60 individuals): active-duty personnel veterans, further subdivided by age into those...
Asthenia, asthenic syndrome, condition, reaction, disorders are terms that describe the state of «impotence». Fatigue occurs against background habitual physical or intellectual stress for a person, and persists after rest, is asthenia. For people older age group, term senile asthenia syndrome used. Asthenia manifests itself with increased fatigue exhaustion, mood instability, irritability, sleep disorders. Asthenic conditions manifest themselves along decrease in activity, cognitive mental...
Understanding the major pathological pathways and key molecules involved in pathogenesis of inflammatory processes joints, particularly osteoarthritis (OA), is crucial for drug pharmaconutraceuticals development. OA a degenerative joint disease that predominantly affects articular cartilage. Destruction hyaline cartilage restructuring subchondral bone are accompanied by synovial inflammation joint, including facet spine, manifested pain low back (LBP), limitation functional activity. The...
Введение. Остеоартрит является одним из наиболее распространенных хронических заболеваний опорно-двигательного аппарата во всем мире и частой причиной развития хронического болевого синдрома инвалидности. Входящие в состав ряда фармаконутрицевтиков хорошо известные молекулы, такие как хондроитина сульфат, глюкозамина сульфат неденатурированный коллаген II типа, обладают подтвержденными эффектами отношении суставного хряща, субхондральной кости, синовии. Применение данных молекул позволяет...
The review examines pharmacological agents that can have potential disease-modifying osteoarthritis drugs (DMOADs) status. DMOADs prevent the progression and further structural joint damage (structure-modifying effect), leading to a decrease in symptoms severity (symptom-modifying such as pain, improvement of function. Approaches selection are discussed: (1) preferred target (bone, cartilage, synovia); (2) action drug mechanism/anti-cytokine therapy (matrix metalloproteinase inhibitors,...
Insufficiency of a choline derivative (acetylcholine) can lead to the development cognitive impairment (CI). One most well-known and well-studied medical drugs (MD) containing having neuroprotective properties is citicoline (Recognan). A number studies have demonstrated effectiveness Recognan in relation mild CI, chronic cerebrovascular diseases (CVD), acute vascular disorders (including post-traumatic genesis). improves memory other functions healthy young people against background asthenia...
In preclinical and clinical studies, choline alfoscerate (CA) has proven to be highly effective in the correction of cognitive impairment (CI). The effect CA is seen improvement mental activity, concentration, ability remember recall information, behavioural responses, elimination emotional instability apathy. Experimental studies have shown effectiveness preventing atrophic changes cerebral cortex. Based on several conducted use treatment CI, it can concluded that oral administration at a...
Pain syndromes, acute and chronic, against the background of inflammatory diseases (such as osteoarthritis (OA)), degenerative-dystrophic changes (involutive process, trauma) or systemic (rheumatoid arthritis, etc.) dictate a steady increase in intake nonsteroidal anti-inflammatory drugs (NSAIDs). The choice most «safe NSAID» is based on assessment toxicity index (the ratio when blocking cyclooxygenase (COX)) development relative risks benefit/risk ratio). As well those adverse events that...
The article presents new views on the treatment of pain syndromes in musculoskeletal diseases, particular osteoarthritis (OA) various localizations (gonarthrosis, coxarthrosis). New recommendations (2019–2020) international societies for study symptomatic delayedacting drugs (SYSADOA) and their use OA are presented. We present opinions experts from different communities: American College Rheumatology (ACR, 2019), European Alliance Associations (EULAR, Society Clinical Economic Aspects...
Objective. To analyze effectiveness of the original complex psychocorrection and transcutaneous electrical neurostimulation (TENS) in patients with post-stress disorders. Materials methods. The study involved 120 men whose professional activity is associated a high level stress. participants were divided into 2 groups depending on their age: younger than 40 years (n=60) older 55 (n=60). Patients underwent clinical examination, psychological testing, examination cardiovascular activity. At...
INTRODUCTION. The choice of optimal therapy for chronic lower back pain includes: influence on all links the vicious circle, has analgesic and anti-inflammatory effects, chondroprotective effect. AIM. A retrospective comparative analysis outpatient records patients with a course drugs containing chondroitin sulfate – Chondroguard, bioactive concentrate small marine fish Alflutop. MATERIAL AND METHODS. Outpatient who took Chondroguard Alflutop in period from January 2022 to April 2024 were...
The article is devoted to the combined use of psychological relaxation and transcutaneous electrical stimulation in post-stress disorders persons hazardous professions. Materials methods . There were 90 men with a high level stress aged 40 55 years, whose clinical picture was distinguished by interweaving neuropsychiatric cardiovascular disorders. assessment mental status patients supplemented results testing; reserve capabilities body assessed based on test dosed physical activity. Electro-...
Osteoarthritis (OA) is a disease of the entire joint, including structural changes in hyaline articular cartilage, subchondral bone, ligaments, capsule, synovial membrane and periarticular muscles. One causes development nonspecific chronic lower back pain (LBP) OA facet joints. In treatment LBP against background joints, chondroprotective agents are widely used: chondroitin sulfate (CS), glucosamine sulfate, undenatured type II collagen their combinations. The aim article to systematize...
Введение. Статья затрагивает вопросы механизмов и результативности немедикаментозной коррекции постстрессовых расстройств у лиц опасных профессий. Материалы методы. Под наблюдением находились 90 мужчин с высоким уровнем профессионального стрессирования в возрасте от 35 до 45 лет, клиническая картина болезни которых отличалась переплетением нервно-психических кардиоваскулярных нарушений. При этом клиническую оценку психического состояния отобранных исследование сопоставляли результатами...
A significant proportion of patients who have had COVID-19 continue to suffer from persistent symptoms such as severe weakness, shortness breath, joint pain, mood swings and memory impairment during the recovery phase. More than half experienced pain for first time after COVID-19. Three months episode, continued occur in more a third patients. We observed 47-year-old patient with moderate shoulder that occurred The examination also revealed changes hip joint. diagnosis was made: post-COVID...
Medical rehabilitation of children suffering from bronchial asthma is based on the complex use natural therapeutic factors, drug, non-drug therapy and other methods in order to achieve control over disease long-term remission. The technologies necessary taking into account pathogenesis development aimed at relieving bronchospasm, reducing activity allergic inflammation bronchi, improving their drainage function, strengthening respiratory muscles increasing exercise tolerance. When carrying...
Over the last 15 years 40 dissertations on traditional medicine, in particular – reflexology, were presented Dissertation Council at Russian Scientific Center “Medical rehabilitation and balneology". Among them, 11 works competition of a scientific degree doctor Sciences 31 candidate Sciences.
 Thesis presentation chronological order is as follows: 2001 4 works; 2003 7 ; 2004 6; 2005 3; 2006 2; 2007 1; 2008 2009 5; 2010 2011 2012 2013 1 and, finally, 2014 2. Thus, there has been...
The present study included 94 patients presenting with bronchial asthma (BA) who underwent the controlled treatment during one year. consisted of basal anti-asthmatic therapy in combination acupuncture reflexotherapy or a complex non-invasive reflexotherapeutic methods (CNIRTM) designed to increase effectiveness correction asthma, improve clinical status patients, decrease by more than two-fold frequency unstable episodes disease showing well-apparent seasonal dependence, and diminish...
В работе детализированы варианты постстрессовых нарушений у представителей опасных профессий (сотрудников силовых ведомств, участников ликвидации последствий катастрофы на Чернобыльской АЭС) и этой основе обоснованы адекватные способы коррекции данных сдвигов. ходе исследования из 1250 мужчин, связанных по роду деятельности со стрессированием, было отобрано 490 лиц, отличающихся переплетением нервно-психических кардиоваскулярных нарушений. С учетом поставленных задач оценивали психический...
Osteoarthritis (OA) is the most common joint disease globally, and its incidence increases with age – up to 80–90% in people over 60 years. There a high comorbidity between OA cardiovascular diseases (CVD), such as arterial hypertension (AH), atherosclerosis, coronary heart (CHD). The main objectives of therapy include pain reduction, cartilage matrix preservation, safe profile patients comorbid diseases, minimal adverse effects. In addition, drug should be comparable analgesic effects...
The results of numerous studies allow us to conclude that atopic dermatitis is one the most common inflammatory skin diseases in children. Most often, debuts at an early age and its prevalence child population can reach 1030%. Scientific forecasts, as well data from various researchers, indicate not only a significant increase number patients, but also worsening course dermatitis, which causes high medical social significance problem this disease. main manifestations disease are itching,...
The presence in children with bronchial asthma of disorders patency, hypersecretion, deterioration the drainage function bronchi determines need to develop new technologies kinesotherapy aimed at cleansing tree from viscous sputum, strengthening chest muscles. In this regard, use high-frequency thoracic oscillation is promising. Purpose. Study effectiveness high frequency asthma. Materials and methods. 60 aged 6 17 years were examined. main group was 30 who received exposure oscillation,...