A5067807903- Hemophilia Treatment and Research
- Neuroblastoma Research and Treatments
- Cancer, Hypoxia, and Metabolism
- Platelet Disorders and Treatments
- Cancer therapeutics and mechanisms
- Blood groups and transfusion
- Virus-based gene therapy research
- Lymphoma Diagnosis and Treatment
- Glycosylation and Glycoproteins Research
- Viral-associated cancers and disorders
- Hepatocellular Carcinoma Treatment and Prognosis
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cytomegalovirus and herpesvirus research
- Hemostasis and retained surgical items
- Orbital Angular Momentum in Optics
- Immunodeficiency and Autoimmune Disorders
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Blood donation and transfusion practices
- CNS Lymphoma Diagnosis and Treatment
- Hepatitis C virus research
- Liver physiology and pathology
- Parvovirus B19 Infection Studies
- Blood Coagulation and Thrombosis Mechanisms
- Cancer Research and Treatments
- Hemoglobinopathies and Related Disorders
Nagoya University
2023
Shizuoka Children's Hospital
2000-2012
Palmetto Hematology Oncology
2001-2006
Boston Children's Hospital
2006
University of Shizuoka
1998
Abstract Background Reports of non‐anaplastic peripheral T‐cell lymphoma (PTCL) in pediatric patients are relatively rare. Procedure We performed a retrospective analysis with PTCL over an 18‐year period (1991–2008). Results could analyze clinical data 21 PTCL; 10 were female and male. Median age onset was 11 years (range: 1–21 years). There nine PTCL, not otherwise specified (PTCL‐NOS); ten extranodal NK/T‐cell lymphoma, nasal type; one angioimmunoblastic lymphoma; subcutaneous...
Summary We reported the results of a clinical pharmacological study MC 710 (a mixture plasma‐derived FVII and FX ) in haemophilia patients with inhibitors during non‐haemorrhagic state. This report provides clot waveform analysis ( CWA thrombin generation test TGT using blood samples obtained this study. were conducted from pharmacokinetic pharmacodynamic which (five dose rates: 20, 40, 80, 100 120 μg kg −1 was compared NovoSeven (120 FEIBA (two 50 75 U as control drugs 11 without...
Summary. MC710, a combined product of plasma‐derived activated factor VII (FVIIa) and X (FX) at protein weight ratio 1:10, is novel bypassing agent for haemostasis in haemophilia patients with inhibitors. In this study, pharmacokinetic (PK), pharmacodynamic (PD) parameters safety single doses MC710 were investigated 11 male inhibitors non‐bleeding state. This was multi‐centre, open‐labelled, non‐randomized, active controlled crossover, dose‐escalation study five (20–120 μg kg −1 FVIIa)...
Approximately 30% of patients with hemophilia in Japan were infected human immunodeficiency virus (HIV) early 1980s through contaminated blood products. In 1995, a cohort HIVinfected, asymptomatic was set up for follow-up study. Although the met criteria long-term non-progressor (LTNP) at entry to cohort, some them later developed lymphopenia during five more years observation. We collected samples from 80 survivors; 42 did not require antiviral therapy, but rest under treatment. Analysis...
Young's double-slit interference experiments with undulator vortex radiation were conducted, focusing on photon-counting regime. To isolate the second harmonic in ultraviolet range emitted from helical and achieve successful counting measurements, an ultranarrow bandpass filter was utilized under extremely low-current mode of electron storage ring. It observed that photon spots detector, after passing through double slits, appeared to be randomly distributed. However, upon integrating these...
Neuroblastoma is the most common extracranial solid tumor in childhood. Spontaneous regression has been well described infants, especially those with stage 4S and low-stage neuroblastoma detected by screening. However, presenting intracranial metastasis generally considered to need a postoperative chemotherapy. Here, we report 3-month-old girl 4 spontaneous of metastatic including meningeal after gross resection primary tumor. Further investigation may be required detect patients this kind...
Abstract Background: In Japan, mass screening for neuroblastoma has been performed at 6 months of age to improve the prognosis this condition more than 20 years. recent years, most neuroblastomas detected by were considered have favorable biological features and sometimes tend regress spontaneously. Methods: The authors established non‐treated observation criteria in 1997 residual tumor after first‐line chemotherapy 1999, made an effort reduce intensity medical treatment neuroblastoma....
The amount of human cytomegalovirus (CMV) DNA in sera is considered to be a direct marker for CMV infection. We established conditions nested PCR that detected one copy DNA, and competitive PCR, which five or more copies quantitatively. tested 50 μl each 16 freeze-stored 5 fresh from patients, DNA. In obtained the same patient at different time points, small amounts were before onset pneumonia. certain CMV-in-fected patients who treated with anti-CMV agent, ganciclovir, was not detected....