A5039746522- Lung Cancer Diagnosis and Treatment
- Advanced Fluorescence Microscopy Techniques
- Single-cell and spatial transcriptomics
- Cell Image Analysis Techniques
- Musculoskeletal pain and rehabilitation
- Advanced MRI Techniques and Applications
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Spine and Intervertebral Disc Pathology
- Muscle and Compartmental Disorders
- Cardiomyopathy and Myosin Studies
- Multiple Sclerosis Research Studies
- Hip disorders and treatments
- Sarcoidosis and Beryllium Toxicity Research
- Electrolyte and hormonal disorders
- Functional Brain Connectivity Studies
- Soft tissue tumor case studies
- Effects of Radiation Exposure
- Cervical and Thoracic Myelopathy
- Orthopedic Surgery and Rehabilitation
- Medical Imaging and Analysis
- Breast Cancer Treatment Studies
- Cardiovascular Function and Risk Factors
- Peripheral Neuropathies and Disorders
- Hemodynamic Monitoring and Therapy
Cappagh National Orthopaedic Hospital
2023-2024
Mater Misericordiae University Hospital
2024
Beaumont Hospital
2024
St. Vincent's University Hospital
2021-2023
Rice University
2013-2022
St. Paul's Hospital
2022
University College Dublin
2022
Queen Mary University of London
2016
Queen Elizabeth Hospital Birmingham
2016
Barts Health NHS Trust
2016
We introduce cytoNet, a cloud-based tool to characterize cell populations from microscopy images. cytoNet quantifies spatial topology and functional relationships in communities using principles of network science. Capturing multicellular dynamics through graph features, also evaluates the effect cell-cell interactions on individual phenotypes. demonstrate cytoNet’s capabilities four case studies: 1) characterizing temporal neural progenitor during differentiation, 2) identifying...
Controlling endogenous angiogenesis, or the formation of new capillaries, is a potential therapeutic strategy for numerous diseases including cancer, stroke and cardiovascular disease (1–4). These efforts have been met with mixed success in clinic, partly due to an inadequate understanding, thus control, mechanisms that influence endothelial cells form capillaries (1, 3). In order control angiogenesis effort improve treatment responses, quantitative information about cell behavior must be...
Abstract We introduce cytoNet, a cloud-based tool to characterize cell populations from microscopy images. cytoNet quantifies spatial topology and functional relationships in communities using principles of network science. Capturing multicellular dynamics through graph features, also evaluates the effect cell-cell interactions on individual phenotypes. demonstrate cytoNet’s capabilities four case studies: 1) characterizing temporal neural progenitor during differentiation, 2) identifying...
To describe the clinical characteristics and treatments associated with antibody positive optic neuropathies including anti-myelin oligodendrocyte glycoprotein (MOG) anti-aquaporin 4 (AQP4), alongside diagnostic modalities, investigations, outcomes.
Abstract Objectives To assess if brake response times are altered pre and post CT-guided cervical spine nerve root injections. Methods Brake were assessed before after injections in a cohort of patients. The average 3 was recorded 30 min injection. Statistical analysis performed using GraphPad. A paired Student t-test used to compare the Results Forty patients included this study. mean age 55 years. There 17 male 23 female no significant difference injection times; 0.94 s (range 0.4-1.2 s)...
Lumbar disc herniation, potentially leading to nerve root compression and cauda equina syndrome, is typically evaluated using MR imaging. However, the limited availability of imaging outside regular hours in certain health care systems poses considerable challenges. This purpose this study was prospectively evaluate diagnostic accuracy an optimized CT lumbar spine protocol as a potential alternative assessing suspected neural compression. Patients presenting emergency department with...
We report the case of a 50-year old woman with known history lipodystrophy. A pelvic radiograph was taken for investigation right hip pain. The image shown demonstrates an indeterminate artefact projected over iliac fossa. previous CT renal study reviewed, demonstrating same device in subcutaneous tissues contralateral left lower quadrant which on close inspection consistent continuous glucose monitoring device. Features lipodystrophy were also noted review imaging. Although many devices...
Early detection of lung cancer recurrence on imaging is critical for better clinical prognosis. The 'enhancing nodule in post-radiation fibrosis sign' an important sign which helps detect recurrent early CT chest.
We introduce cytoNet, a method to characterize multicellular topology from microscopy images. Accessible through web-based interface, cytoNet quantifies the spatial relationships in cell communities using principles of graph theory, and evaluates effect cell-cell interactions on individual phenotypes. demonstrate cytoNet’s capabilities two applications relevant regenerative medicine: quantifying morphological response endothelial cells neurotrophic factors present brain after injury,...
Abstract Introduction: Historically, multiple synchronous breast cancers are defined as multifocal (MF) when they aoccur in the same quadrant of breast, and multicentric (MC) different quadrants; a number authors continue to use this distinction. Multifocality has been reported be an independent prognostic factor for survival local recurrence. The molecular implications MF MC versus univocal remain defined. We sought investigate incidence basis phenomenon. Materials methods: Following...
Chronic exertional compartment syndrome is well documented in the distal extremities, but rare thighs. We present case of a 19-year-old male who presented with chronic, recurrent bilateral thigh pain induced by physical activity, which settled rest recurred on immediate return to exercise. Postexercise MRI both thighs demonstrated changes symmetrical edema proximal quadriceps muscles, reflecting exercise-induce syndrome. The patient underwent selective fasciotomies each anterior improvement...
‘Soft’ start flow distribution, control capability, sealing performance, and safety, were four reasons Oklahoma Municipal Power Authority (OMPA), in cooperation with Black & Veatch Vogt, installed Dual BiPlane Heat Recovery Steam Generator (HRSG) Isolation Bypass Dampers from Damper Design, Inc. on the gas turbine outlet at this facility. The DDI damper is truly a unique for application. This design allowed OMPA to have safety isolation of flap diverter white providing even distribution...