- Pain Management and Opioid Use
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Nausea and vomiting management
- Pediatric Pain Management Techniques
- Pain Mechanisms and Treatments
- Safe Handling of Antineoplastic Drugs
- Pharmaceutical studies and practices
- Cancer Treatment and Pharmacology
- Medication Adherence and Compliance
- Pain Management and Placebo Effect
- Contact Dermatitis and Allergies
- Helicobacter pylori-related gastroenterology studies
- Botulinum Toxin and Related Neurological Disorders
- Forensic Toxicology and Drug Analysis
- Chemotherapy-related skin toxicity
- Drug-Induced Adverse Reactions
- Pharmaceutical Practices and Patient Outcomes
- Neuroendocrine Tumor Research Advances
- Protein purification and stability
- Epilepsy research and treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Gastroesophageal reflux and treatments
- Chemical Safety and Risk Management
Institut de Cancérologie de l'Ouest
2016-2024
Institut Génétique Nantes Atlantique
2019
Centre Hospitalier Universitaire d'Angers
2014
Abstract Background The association of morphine and baclofen is used for the treatment spasticity related pain. Moving these patients sometimes difficult. In order to transport syringes pump refilling, it could be interesting demonstrate stability mixture, so able ensure best conditions syringes. Methods A indicating UPLC-DAD method was developed validated according ICH guidelines. Two mixtures – a low concentration mixture (morphine 1 mg/mL 0.08 mg/mL) high 10 1.6 stored in 5±3 °C 25±2 were...
Abstract Intrathecal analgesia has increased over the past two decades based on high level proof of efficacy in patients with cancer. Morphine and Ziconotide remains reference. Polyanalgesic Consensus Conference IT treatment algorithm recommends as second line therapy opioids/ziconotide combination. Sufentanil ziconotide combination can be used. The implantable pumps development helped to improve comfort patient. refills were prepared under a laminar airflow hood strictly aseptic conditions,...
Abstract Intrathecal analgesia has increased over the last 30 years. In oncology, it is a real alternative for treatment of refractory pain. The diversity molecules alone or in combination that can be used, risk related to route administration, and cost certain are all arguments favor centralized preparation within pharmacy. purposes this work first explain reasons centralization these preparations, second time describe circuit developed our establishment.
<h3>Background</h3> Docetaxel is an antineoplastic agent widely used in combination with others cytotoxic agents many cancers (breast cancer, non-small cell lung prostate etc.). Today, this costly marketed by several pharmaceutical companies who suggest discarding any remainder immediately after use, making it a very drug. <h3>Purpose</h3> The aim of study was to determine the physical-chemical stability docetaxel stock solution first sampling vial. <h3>Materials and methods</h3> conducted...