A5019454882- Ocular Surface and Contact Lens
- Corneal Surgery and Treatments
- 3D Printing in Biomedical Research
- Ocular Disorders and Treatments
- Ocular Diseases and Behçet’s Syndrome
- Transplantation: Methods and Outcomes
- Organ and Tissue Transplantation Research
- Retinal Development and Disorders
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Advanced Drug Delivery Systems
- Immunodeficiency and Autoimmune Disorders
- Cancer Immunotherapy and Biomarkers
- Organ Transplantation Techniques and Outcomes
- Salivary Gland Disorders and Functions
- Erythrocyte Function and Pathophysiology
- Nanoplatforms for cancer theranostics
- Innovative Microfluidic and Catalytic Techniques Innovation
- Blood groups and transfusion
- Olfactory and Sensory Function Studies
- Bone Tissue Engineering Materials
- Head and Neck Cancer Studies
- Acne and Rosacea Treatments and Effects
- Connexins and lens biology
- Chronic Lymphocytic Leukemia Research
Université de Sherbrooke
2022-2025
Georgia Southern University
2024
University of Georgia
2024
Armstrong Atlantic State University
2024
Johns Hopkins University
2019-2023
Johns Hopkins All Children's Hospital
2019-2023
University of South Florida
2013-2022
AbbVie (United States)
2021-2022
Université Laval
2020-2022
McGill University
2018-2020
The aim of the current study was to assess economic impact using next-generation sequencing (NGS) versus single-gene testing strategies among patients with metastatic non-small-cell lung cancer (mNSCLC) from perspective Centers for Medicare & Medicaid Services (CMS) and US commercial payers.A decision analytic model considered who were newly diagnosed mNSCLC received programmed death ligand 1 genomic alteration tests-EGFR, ALK, ROS1, BRAF, MET, HER2, RET, NTRK1-using upfront NGS (all...
Abstract During the COVID‐19 pandemic, dental education community faced unprecedented challenges. In this commentary, we share perspectives of faculty clinicians, residents and students in academic institutions United States Canada. We discuss COVID‐19’s impact on various aspects dentistry including patient care, education, research raise key concerns regarding future post‐pandemic.
Abstract This comprehensive review delves into a unique intersection of hydrogels as smart molecules and their transformative applications in ophthalmology. Beginning with the foundational definition, properties, classification hydrogels, explores synthesis responsive capabilities. Specific examined encompass topical drug delivery, contact lenses, intravitreal ocular adhesives, vitreous substitutes, cell‐based therapy. A methodical analysis, including an overview relevant structures...
Aberrant elevation in the levels of pro-inflammatory cytokine interleukin-1β (IL-1β) contributes to neuroinflammatory diseases. Blood-brain barrier (BBB) dysfunction is a hallmark phenotype neuroinflammation. It known that IL-1β directly induces BBB hyperpermeability but mechanisms remain unclear. Claudin-5 (Cldn5) tight junction protein found at endothelial cell-cell contacts are crucial for maintaining brain microvascular cell (BMVEC) integrity. Transcriptional regulation Cldn5 has been...
Nonspecific orbital inflammation (NSOI), colloquially known as pseudotumor, sometimes presents a diagnostic and therapeutic challenge in ophthalmology. This review aims to dissect NSOI through molecular lens, offering comprehensive overview of its pathogenesis, clinical presentation, methods, management strategies. The article delves into the underpinnings NSOI, examining immunological environmental factors alongside intricate mechanisms involving signaling pathways, cytokines, mediators....
The integration of functional biomaterials in oculoplastic and orbital surgery is a pivotal area where material science clinical practice converge. This review, encompassing primary research from 2015 to 2023, delves into the use two key areas: reconstruction floor fractures development implants prostheses for anophthalmic sockets post-eye removal. discussion begins with an analysis injuries, including their pathophysiology treatment modalities. It noted that titanium mesh remains gold...
The recombination-activating genes (RAG) 1 and 2 are indispensable for diversifying the primary B cell receptor repertoire pruning self-reactive clones via editing in bone marrow; however, impact of RAG1/RAG2 on peripheral tolerance is unknown. Partial RAG deficiency (pRD) manifesting with late-onset immune dysregulation represents an 'experiment nature' to explore this conundrum. By studying development subset-specific repertoires pRD, we demonstrate that reduced activity impinges through...
Thyroid Eye Disease (TED) is a debilitating autoimmune condition characterized by significant inflammation of orbital tissues, including the extraocular muscles and adipose tissues. The pathological mechanisms underlying this involve complex interplay stress responses at cellular molecular level. This review aims to critically evaluate synthesize existing literature on in TED. We discuss role autoantibodies, cytokines, reactive oxygen species (ROS) initiation propagation inflammatory...