Glutathione has been regarded as a significant signal for distinguishing between tumor and normal tissue. Recently, reactive oxygen species have attracted much attention their close connection with many diseases. Taking advantage of the physiological signals, redox-responsive polymeric drug carriers constitute research area in various stimuli-responsive polymers biomedical applications. During rapid development polymers, molecular design related synthetic methodology plays crucial role. In...

Two end-decorated homopolymers, poly(styrene)-β-cyclodextrin (PS-β-CD) and poly(ethylene oxide)-ferrocene (PEO-Fc), can orthogonally self-assemble into a supramolecular diblock copolymer (PS-β-CD/PEO-Fc) in aqueous solutions based on the terminal host−guest interactions. These assemblies further form vesicles, their assembly disassembly behaviors be reversibly switched by voltage through reversible association disassociation of middle connection. The vesicles possess an unprecedented...

In nature, hierarchically assembled nanoscale ionic conductors, such as ion channels and pumps, become the structural functional basis of bioelectric phenomena. Recently, ion‐channel‐mimetic nanofluidic systems have been built into reconstructed 2D nanomaterials for energy conversion storage effective electrogenic cells. Here, a 2D‐material‐based reverse electrodialysis system, containing cascading lamellar nanochannels in oppositely charged graphene oxide membrane (GOM) pairs, is reported...

Abstract To face the increasing demand of self‐healing hydrogels with biocompatibility and high performances, a new class cellulose‐based are constructed through dynamic covalent acylhydrazone linkages. The carboxyethyl cellulose‐ graft ‐dithiodipropionate dihydrazide dibenzaldehyde‐terminated poly(ethylene glycol) synthesized, then formed from their mixed solutions under 4‐amino‐DL‐phenylalanine (4a‐Phe) catalysis. chemical structure, as well microscopic morphologies, gelation times,...

Schiff-base reactions are widely used in the field of chemistry. With many advantages, such as mild reaction conditions and high rates, they were employed for protecting various functional groups synthesizing a series organic ligands. In polymer chemistry, can serve potential pH-responsive linkers chains because their sensitive responses to changes pH value. certain particular designs, structure cooperate with other reversible covalent bonds or supra-molecular interactions form assemblies...

Abstract Responsive polymer interfacial materials are ideal candidates for controlling surface wetting behavior. Here we developed smart nanostructured electrospun membranes which capable of switching oil/water wettability using CO 2 as the trigger. In particular, combination ‐responsiveness and porous nanostructure enables as‐prepared to be used a novel on–off switch. We anticipate that promising versatility simplicity this system would not only open up new way change regulation by gas, but...

Vesicles breathe CO2! A new type of vesicle that self-assembles from amidine-containing diblock copolymer displays “breathing” features. Treating the vesicles with CO2 or Ar can reversibly tune expansion and contraction vesicular volume, as if a bubble is breathing (see picture, PAD=poly((N-amidino)dodecyl acrylamide), PEO=poly(ethylene oxide), Rh=hydrodynamic radius). Detailed facts importance to specialist readers are published ”Supporting Information”. Such documents peer-reviewed, but...

Understanding of the functions enzymes in diverse cellular processes is important, but design sensors with controllable localization for situ imaging subcellular levels enzymatic activity particularly challenging. We introduce herein a spatiotemporally controlled sensor technology that permits and photoactivated human apurinic/apyrimidinic endonuclease 1 (APE1) within an intracellular organelle choice (e.g., mitochondria or nucleus). The hybrid platform constructed by photoactivatable...

Cellulose-graft-poly(N,N-dimethylamino-2-ethyl methacrylate) (cellulose-g-PDMAEMA) copolymers were prepared by homogeneous atom transfer radical polymerization (ATRP) under mild conditions. Cellulose macroinitiator was successfully synthesized direct acylation of cellulose with 2-bromopropionyl bromide in a room temperature ionic liquid (RTIL), 1-allyl-3-methylimidazolium chloride. Copolymers obtained via ATRP N,N-dimethylamino-2-ethyl methacrylate (DMAEMA) CuBr/...

Take a deep breath: The membrane permeability and the scale of nanochannels polymer vesicles are modulated by CO2 control vesicular expansion contraction. These polymersomes can act as size-selective nanoseparators for particle sieving nanoreactors enzymatic reactions that require compartmentalization. GSH=glutathione.

Superparamagnetic iron oxide nanoparticles have received great research attention due to their wide spectrum of potential applications. Core–shell structures with as the core and covalently grafted organic polymers shell, which has specific functions, such biocompatibility, fluorescence, biological activity been synthesised. These nanostructured compounds could find numerous biomedical This feature article provides a review on synthetic methodologies for building magnetic core–shell...

Poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) with a β-cyclodextrin (β-CD) at the chain end was synthesized via atom transfer radical polymerization (ATRP); poly(ε-caprolactone) (PCL) −C═C– segment and an adamantane (Ada) group two ends, respectively, prepared through ring-opening (ROP), poly(N-isopropylacrylamide) (PNIPAM) −S–C(S)–S– segment, which can be converted into thiol group, yielded by reversible addition–fragmentation (RAFT). A supramolecular triblock stimuli-responsive...

Cellulose nanofibers (CNFs) aerogels with controllable surface wettability were prepared by grafting poly( N, N-dimethylamino-2-ethyl methacrylate) (PDMAEMA) polymer brushes via surface-initiated atom-transfer radical polymerization. After PDMAEMA polymer, the of aerogel was hydrophobic. However, in presence CO2, gradually changes from hydrophobic to hydrophilic. The porous structure and CO2-responsiveness within CNFs allowed for on-off switching oil-water mixture separation process. These...

Abstract A one‐step synthesis of nanotubes by RAFT dispersion polymerization cyclodextrin/styrene (CD/St) complexes directly in water is presented. The resulted amphiphilic PEG‐b‐PS diblock copolymers self‐assemble situ into nanoparticles with various morphologies. Spheres, worms, lamellae, and were controllably obtained. Because the complexation, swelling degree polystyrene (PS) blocks free St limited, resulting limited mobility PS chains. Consequently, kinetically trapped lamellae obtained...

β-Cyclodextrin-modified hybrid magnetic nanoparticles (Fe3O4@SiO2-PGMACD) were synthesized via the combination of atom transfer radical polymerization on surfaces silica coated iron oxide particles (Fe3O4@SiO2) and ring-opening reaction epoxy groups. The feasibility using Fe3O4@SiO2-PGMACD as separable immobilized catalyst adsorbent was demonstrated. It found: (1) prepared could be used in substrate-selective oxidation alcohols system catalytic efficiency close to pure β-Cyclodextrin equal...

Two homopolymers can orthogonally self-assemble into pseudo-copolymer based on terminal host–guest interactions, and these supramolecular copolymers further fabricate one-dimensional nanotubes in water. By applying alternate UV/visible light, the aggregates reversibly assemble disassemble by means of association disassociation active connection.

Electrochemical stimuli have attracted much attention in recent years as they are simple, clean and can be widely applied biological systems material science. As one type of common guest molecules, ferrocene its derivatives been well studied with different host mainly including cyclodextrins, cucurbiturils, pillararenes calixarenes. This article generally summarizes the work on host-guest interactions between their various supramolecular based these interactions. In addition, development...

The correlation of aggregation-induced emission (AIE) to the nanostructure polymer assemblies was investigated. A series AIE-active PDMA-b-P(BzMA-TPE) [PDMA: poly(N,N-dimethylaminoethyl methacrylate); P(BzMA-TPE): poly[benzyl methacrylate-co-1-ethenyl-4-(1,2,2-triphenylethenyl)benzene]] with controlled nanostructures were prepared via polymerization-induced self-assembly BzMA and TPE, an AIEgen, in presence PDMA macro-chain-transfer agents. We found that fluorescence intensity fluorescent...

Mesogen-containing amphiphilic block copolymers have shown extremely abundant self-assembly behaviors because of the liquid crystalline (LC) alignment within assemblies. However, development an understanding these LC polymers is still constrained by low assembly concentration and complex kinetic effects. Polymerization-induced (PISA) a powerful technique to prepare polymer assemblies at high solids content with good repeatability. Taking advantage PISA, we systematically study series...

Abstract Photoactuators based on liquid crystal elastomers or networks are smart materials that show photoinduced motions. However, their crosslinked make repair reprocessing difficult. Here, a healable and reprocessable photoactuator is fabricated using entangled high‐molecular‐weight azobenzene‐containing polymers (azopolymers) non‐crosslinked. A series of linear azopolymers with different molecular weights synthesized. The low‐molecular‐weight (5–53 kg mol −1 ) cannot form freestanding...

Stimuli responsive polymers have been extensively studied as nanocarriers for drug delivery systems (DDSs), especially those based on supramolecular interactions. Cyclodextrin (CD) is one kind of widely applied host molecule, and the host-guest interactions between CD different counterparts can respond to stimuli thus be linkers polymeric DDSs. In this review, ferrocene, azobenzene, benzimidazole DDSs are summarized, with redox, light, pH sensitivity, respectively. The mechanisms ability...

CO2-responsiveness is imported into amphiphilic block copolymers, poly[(N,N-diethylaminoethyl methacrylate)-b-(N-isopropylacrylamide)] (PDEAEMA-b-PNIPAM), and a system dual-responsive to CO2 temperature constructed. The copolymer self-assembles in aqueous solution, undergoes phase transition when stimuli occur, since the give rise conversion of hydrophilicity both blocks. Combining as triggers, schizophrenic micelle vesicle morphological polymer assemblies controlled.