Nicolas Giraud

ORCID: 0000-0002-1669-9093
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About
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Research Areas
  • Prostate Cancer Diagnosis and Treatment
  • Prostate Cancer Treatment and Research
  • Spondyloarthritis Studies and Treatments
  • Vasculitis and related conditions
  • Lung Cancer Diagnosis and Treatment
  • Veterinary Orthopedics and Neurology
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Bone and Joint Diseases
  • Platelet Disorders and Treatments
  • Otitis Media and Relapsing Polychondritis
  • Medical Imaging and Pathology Studies
  • Heparin-Induced Thrombocytopenia and Thrombosis
  • Rheumatoid Arthritis Research and Therapies
  • Lung Cancer Treatments and Mutations
  • Myeloproliferative Neoplasms: Diagnosis and Treatment
  • Reproductive Biology and Fertility
  • Radiomics and Machine Learning in Medical Imaging
  • Urologic and reproductive health conditions
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Virology and Viral Diseases
  • Machine Learning in Healthcare
  • Surgical Sutures and Adhesives
  • Polyomavirus and related diseases
  • Osteomyelitis and Bone Disorders Research
  • Maritime Navigation and Safety

Institut Bergonié
2021-2023

Amsterdam University Medical Centers
2023

University of Amsterdam
2023

Cancer Center Amsterdam
2023

Institut Gustave Roussy
2023

Centre Hospitalier Universitaire de Besançon
2019-2022

VetAgro Sup
2020-2021

Université Claude Bernard Lyon 1
2020-2021

Association Française de Chirurgie
2021

McGill University
2021

SABR performed for central and ultracentral lung tumors is associated with increased toxicity but limited data available on late toxicities. We studied in patients followed-up ≥ 2 years post-SABR at a single-institution.All were treated using VMAT primary or recurrent cancer between 2008-2015. 60 Gy was delivered 8 12 fractions. Grade 3 clinical radiological bronchial scored. Multivariable Cox regression models used to estimate hazard ratios.Of 127 eligible patients, 63% Median tumor...

10.1016/j.radonc.2023.109848 article EN cc-by Radiotherapy and Oncology 2023-08-09

Higher toxicity rates are associated with stereotactic ablative radiotherapy (SABR) to central lung tumors. Breath-hold (BH) magnetic resonance-guided SABR (MR-SABR) can reduce doses organs at risk (OAR). We quantified the planning target volumes (PTV) OAR distance in 45 lesions treated using MR-SABR and generated a corresponding four-dimensional computed tomography (4D-CT) based PTV (motion-encompassing internal volume plus 5 mm). For located ≦3 cm from airways, BH increased median by 3.7...

10.1016/j.phro.2025.100761 article EN cc-by Physics and Imaging in Radiation Oncology 2025-04-01

Use of predictive models for the prediction biochemical recurrence (BCR) is gaining attention prostate cancer (PCa). Specifically, BCR occurs in approximately 20-40% patients five years after radical prostatectomy (RP) and ability to predict may help clinicians make better treatment decisions. We aim investigate accuracy CAPRA score compared others predicting 3-year PCa patients.A total 5043 men who underwent RP were analyzed retrospectively. The score, Cox regression analysis, logistic...

10.3389/fonc.2020.607923 article EN cc-by Frontiers in Oncology 2021-02-11

Approximately 30% of patients treated with radical prostatectomy (RP) for prostate cancers experience biochemical recurrence (BCR). Post-operative radiation therapy (RT) can be either offered immediately after the surgery in case aggressive pathological features or proposed early if BCR occurs. Until recently, little data were available regarding optimal RT timing, protocol, volumes to treat, and benefit adding androgen deprivation therapies post-operative RT. In this review, we aim...

10.3389/fonc.2021.781040 article EN cc-by Frontiers in Oncology 2021-11-18

Prostate cancer in younger men is rare but not exceptional. Radiotherapy a cornerstone of prostate treatment and yet, its impact on fertility scarcely reported literature. Given the radiosensitivity testicular tissue, this study aimed to determine dose using modern radiotherapy techniques for definitive irradiation. One hundred plans were reviewed. Testicles contoured retrospectively without dosimetric optimization testicles. The median was 0.58 Gy: 0.18 Gy stereotactic plans, 0.62...

10.1186/s13014-024-02498-3 article EN cc-by-nc-nd Radiation Oncology 2024-08-01

come from teaching and research institutions in France or abroad, public private centers.L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques niveau recherche, publiés ou non, émanant des établissements d'enseignement recherche français étrangers, laboratoires publics privés.

10.5150/jngcgc.2024.049 article FR 2024-01-01

<h3>Background</h3> Polymyalgia rheumatica (PMR) is one of the most common inflammatory rheumatic diseases. To date, there no imaging procedure that can be used as a prognostic factor for good or poor response to corticosteroid therapy <h3>Objectives</h3> evaluate value 18F-fluorodeoxyglucose PET-CT (FDG-PET/CT) score at baseline, on therapeutic prednisone, in patients with polymyalgia (PMR). <h3>Methods</h3> This monocentric retrospective study realized university hospital Besancon. We...

10.1136/annrheumdis-2019-eular.6192 article EN Annals of the Rheumatic Diseases 2019-06-01

<h3>Background:</h3> Imaging techniques in polymyalgia reumatica (PMR) have revealed mainly bursitis, tenosynovitis, capsulitis and enthesitis. This is also the case for 18F-FDG-PET-CT. technique, which has shown its interest diagnosis of PMR, allows an assessment metabolic activity entire musculoskeletal system particular muscle structures. <h3>Objectives:</h3> The objective this work was to evaluate damage using 18F-FDG-PET-CT PMR. <h3>Methods:</h3> a retrospective study including patients...

10.1136/annrheumdis-2019-eular.5256 article EN Annals of the Rheumatic Diseases 2019-06-01

In-field prostate cancer (PCa) oligo-recurrence after pelvic radiotherapy is a challenging situation for which metastasis-directed treatments may be beneficial, but options focal therapies are scarce.We retrospectively reviewed data patients with three or less in-field oligo-recurrent nodal, bone and/or locally recurrent (prostate, seminal vesicles, prostatic bed) PCa lesions radiation therapy, identified molecular imaging (PET MRI) and treated by ablative therapy (cryotherapy...

10.3389/fonc.2021.709779 article EN cc-by Frontiers in Oncology 2021-07-26

Tendon rupture is a common injury in animals, which may lead to severe lameness and pain depending on severity duration. Surgical repair consists re-apposition of the tendon ends using vario...

10.1080/10255842.2020.1812157 article EN cc-by Computer Methods in Biomechanics & Biomedical Engineering 2020-10-19

343 Background: Recent advances in machine learning algorithms and deep solutions paved the way for improved accuracy survival analysis. We aim to investigate of conventional methods prediction 3-year biochemical recurrence (BCR) as compared CAPRA score prediction. Methods: A total 5043 men who underwent RP between 2000 2015 clinically localized PCa iwere analyzed retrospectively. Three-year BCR was predicted using following models: score, Cox regression analysis, logistic regression,...

10.1200/jco.2020.38.6_suppl.343 article EN Journal of Clinical Oncology 2020-02-19

Abstract Background Prostate cancer in younger men is not infrequent. Radiotherapy a cornerstone of prostate treatment and yet, its impact on fertility scarcely reported literature. Since testis one the most radiosensitive tissue, we tried to determine testicular dose with modern radiotherapy techniques for definitive irradiation. Methods hundred plans were reviewed. Testicles contoured posteriori without any optimization testicles. Results Median was 0.58 Gy: 0.18 Gy stereotactic versus...

10.21203/rs.3.rs-3363460/v1 preprint EN cc-by Research Square (Research Square) 2023-09-25

251 Background: For prostate cancer (Pca), salvage radiotherapy (sRT) with or without androgen deprivation therapy (ADT) is currently the only curative treatment option in case of post-radical prostatectomy (RP) biochemical relapse (BR). Functional imaging techniques have shown that macroscopic recurrence (MR) bed (PB) are frequent. In this study, we aimed to assess efficacy and safety sRT patients MR inside PB proven by functional imaging. Methods: A multicenter retrospective study was...

10.1200/jco.2022.40.6_suppl.251 article EN Journal of Clinical Oncology 2022-02-16
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