A5056184179- Musculoskeletal pain and rehabilitation
- Spine and Intervertebral Disc Pathology
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pain Management and Placebo Effect
- Sports injuries and prevention
- Scoliosis diagnosis and treatment
- Health Systems, Economic Evaluations, Quality of Life
- Pain Management and Treatment
- Pain Mechanisms and Treatments
- Myofascial pain diagnosis and treatment
- Research in Social Sciences
- Ergonomics and Musculoskeletal Disorders
- Occupational Health and Performance
- Complementary and Alternative Medicine Studies
- Clinical practice guidelines implementation
- Shoulder Injury and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Pregnancy-related medical research
- Workplace Health and Well-being
- Total Knee Arthroplasty Outcomes
- Orthopedic Surgery and Rehabilitation
- Anesthesia and Pain Management
- Balance, Gait, and Falls Prevention
- Transcranial Magnetic Stimulation Studies
- Healthcare professionals’ stress and burnout
Invalidisäätiö
2009-2025
Rehabilitation Foundation
1989-2020
University of Cape Town
2019
Groote Schuur Hospital
2019
Cairo University
2018
Edward Francis Small Teaching Hospital
2018
Orthopaedic Hospital
2004-2011
The Orthopaedic Institute
2004
Finnish Institute of Occupational Health
2003
Institute for Molecular Medicine Finland
1998
In Brief Study Design. A randomized controlled trial. Objectives. To assess the effectiveness of decompressive surgery as compared with nonoperative measures in treatment patients lumbar spinal stenosis. Summary Background Data. No previous trial has assessed comparison conservative for Methods. Four university hospitals agreed on classification disease, inclusion and exclusion criteria, radiographic routines, surgical principles, options, follow-up protocols. total 94 were into a or group:...
Alterations in tactile sensitivity are common patients with chronic pain. Recent brain imaging studies have indicated that areas activated by acute experimental pain partly overlap processing innocuous stimuli. However, the possible effect of on central has remained unclear. We examined, both clinically and whole-head magnetoencephalography, six suffering from complex regional syndrome (CRPS) upper limb. The cortical somatosensory responses were elicited stimuli applied to fingertips...
A prospective randomized controlled trial.To examine the effectiveness of combined manipulative treatment, stabilizing exercises, and physician consultation compared with alone for chronic low back pain.Strong evidence exists that manual therapy provides more effective short-term pain relief than does placebo treatment in management pain. The long-term effect is lacking.Two hundred four patients, whose Oswestry disability index was at least 16%, were randomly assigned to either a...
A randomized controlled trial.To evaluate the long-term efficacy of infliximab, a monoclonal antibody against tumor necrosis factor alpha (TNF-alpha), in patients with acute/subacute sciatica secondary to herniated disc.The results experimental studies and our open-label trial support use infliximab sciatica. Here we report 1-year (FIRST II, Finnish Infliximab Related STudy) evaluating safety single infusion for sciatic pain.Inclusion criteria were unilateral pain disc herniation concordant...
Association of health locus control beliefs (HLC) and psychological distress (GHQ-12) with short-term outcome low-back pain (LBP) rehabilitation was studied in patients chronic or recurrent LBP (n = 459; aged 35-54 years; 63% men). These were randomly assigned to 3 study groups, namely the inpatient, outpatient group. The results showed a significant decrease disability due 2 treated groups; addition, accomplishment frequency back exercises significantly better groups. HLC associated...
Outcome of inpatient and outpatient treatment low back pain was studied in 459 patients (aged 35-54 years, 63% men); 156 inpatients, 150 outpatients 153 controls. Changes disability caused by it, adherence accomplishment exercises were used as short-term outcome criteria. The overall results showed a significant decrease better compliance the two treated groups when compared to There also difference gains between inpatients outpatients; i.e. greater frequency higher inpatients. estimated...
The long-term outcome results of inpatient and outpatient treatment low back pain (LBP) were studied in 476 subjects (aged 35-54, 63% men) randomly assigned to three study groups: inpatients (n = 157), outpatients 159), controls 160). included changes the severity pain, grade disability, compliance with self-care, data on disability pensions, days sickness allowance during a 2.5-year follow-up period. These variables used as criteria. Pain had decreased significantly two treated groups up...
A study of postural control during one-footed and externally disturbed two-footed stance among healthy subjects patients with chronic low back pain at the beginning a functional restoration program 6 months later follow-up examination.To cross-sectionally pain, to evaluate effects on parameters in examination.Deficits motor skills coordination have been reported association musculoskeletal disorders. It has found that impaired psychomotor control, but impairment is reversible successful...
Study Design. An open-label study was conducted. Objective. To evaluate the efficacy and safety of infliximab, a monoclonal chimeric antibody, against tumor necrosis factor-α (TNFα) for treatment severe sciatica. Summary Background Data. Evidence from animal studies indicates that TNFα plays role in pathophysiology Anti-TNFα therapy has not been previously evaluated sciatic patients. Methods. In this study, 10 patients with disc herniation–induced sciatica received infliximab (Remicade 3...
Study Design Psychomotor speed (reaction time) and postural control (center point of force velocity) among healthy volunteers patients with chronic low back pain (LBP) were studied at the beginning an active, functional, restoration rehabilitation program 6 months after program. Objectives To study cross-sectionally reaction times center points velocity pain, to evaluate effects on these measures motor function in a follow-up examination. Summary Background Data Deficits skills coordination...
Twenty-two adolescent patients with severe (more than 50%) slip were surgically treated. Eleven reduced Magerl/Dick transpedicular screw devices and fused posteriorly from L4 to S1, 2 weeks later anteriorly L5-S1; the other 11 in situ L4-S1 (6 patients) or L5-S1 (5 using a circumferential patients), anterior (4 posterolateral (1 patient) technique without instrumentation. The two groups comparable as age at operation, follow-up, follow-up time, preoperative radiologic measurement of slip,...
In Brief Study Design. An open-label trial. Objectives. To test the long-term efficacy of infliximab, a monoclonal antibody against tumor necrosis factor-alpha (TNF-α), in disc herniation-induced sciatica. Summary Background Data. Our recent trial indicated that single infusion 3 mg/weight-kg infliximab produced rapid curative effect Here, we describe 1-year mg/kg these 10 patients and our experience with lower dose 1 for same indication 2 additional patients. Methods. Patients severe...
In Brief Study Design. A randomized controlled trial. Objectives. To evaluate the efficacy of infliximab, a monoclonal antibody against tumor necrosis factor (TNF)-α in setting. Summary Background Data. Recently, we obtained encouraging results an open-label study infliximab patients with disc herniation-induced sciatica. Furthermore, experimental studies support use Therefore, initiated randomized, trial (FIRST II, Finnish Infliximab Related STudy) to confirm single infusion for sciatic...
The aim of this 12-month follow-up study was to evaluate the effect Swedish-type back school in chronic low pain. 188 subjects completed (95 treatment group and 93 control group). following were assessed: 1) subjective scores pain disability; 2) clinical measurement evaluation including spinal mobility strength measurement; 3) number length sick-leaves. At 12 months, disability, lumbosacral section spine showed differences favour group. There no difference, however, or sick-leaves after...
The present study focuses on the long-term prognosis of radiographically verified stenosis lower lumbar spine. purpose here was to describe outcome 12 years after radiographic diagnosis spinal and identify factors predicting disability operative or conservative treatment. Data were compiled 75 patients (43 men 32 women) with changes in functional myelography diagnostic for stenosis. Their mean age at interview later 61 years. sagittal diameter dural sac measured from baseline myelographs all...
A sample of 508 male and female white-collar blue-collar employees aged 35 to 54 years were examined clinically determine the reliability spinal flexibility measurements using inclinometers a tape measure, normal values cervical sagittal movements, lateral flexion, lumbar flexion extension, trunk rotation sidebending. Spinal decreased with advancing age, particularly among workers. Male predominance was observed in flexion-extension-movement. negatively related experience disabling pain. The...