Hua Huang

ORCID: 0000-0002-1713-8597
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About
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Research Areas
  • Cancer-related gene regulation
  • Medicinal Plant Pharmacodynamics Research
  • Cancer-related Molecular Pathways
  • Immune Cell Function and Interaction
  • Reproductive Physiology in Livestock
  • Sperm and Testicular Function
  • MicroRNA in disease regulation
  • Inflammasome and immune disorders
  • Phytoestrogen effects and research
  • Epigenetics and DNA Methylation
  • Reproductive System and Pregnancy
  • Cancer-related molecular mechanisms research
  • Ferroptosis and cancer prognosis
  • Immunotherapy and Immune Responses
  • Kruppel-like factors research
  • Cancer, Stress, Anesthesia, and Immune Response
  • Enhanced Recovery After Surgery
  • Cancer Immunotherapy and Biomarkers
  • Protein Kinase Regulation and GTPase Signaling
  • Genetic Mapping and Diversity in Plants and Animals
  • Cancer survivorship and care
  • Advanced Breast Cancer Therapies
  • Forest, Soil, and Plant Ecology in China
  • Medicinal Plants and Bioactive Compounds
  • Nutrition and Health in Aging

The People's Hospital of Guangxi Zhuang Autonomous Region
2023-2025

The First Affiliated Hospital, Sun Yat-sen University
2024

Kunming Institute of Botany
2017-2024

Sun Yat-sen University
2024

Anhui Medical University
2023

Affiliated Hospital of Nantong University
2011-2021

Nantong University
2011-2021

Southern Medical University
2020

Nanfang Hospital
2020

Fudan University Shanghai Cancer Center
2016-2018

The objective of this study is to examine the impact marital status on incidence metastasis at diagnosis, receipt surgery, and cause-specific survival (CSS) in patients with gastric cancer (GC). Research data extracted from Surveillance, Epidemiology, End Results (SEER) database, 18,196 diagnosed GC 2004 2010 are involved. Effects CSS determined using multivariable logistic regression Cox models, as appropriate. Single have a higher diagnosis than married patients, while differences between...

10.1002/cam4.758 article EN cc-by Cancer Medicine 2016-06-05

Obesity is a global threat for male infertility, which can cause spermatogenic dysfunction. However, there are no available drugs the treatment of obesity-induced spermatogenesis This study characterizes protective effects icariin (ICA) on dysfunction in obese mice.Obese mice induced by high-fat diet to determine whether ICA has effect. reduces body weight and proportion abnormal sperm, brings about recovery sperm count, number cells. improves histopathological changes testes inhibits...

10.1002/mnfr.202200524 article EN Molecular Nutrition & Food Research 2023-04-14

Cervical cancer remains a global health challenge. The identification of new immunotherapeutic targets may provide promising platform for advancing cervical treatment.

10.1136/jitc-2024-009416 article EN cc-by-nc-nd Journal for ImmunoTherapy of Cancer 2024-10-01

The association between perioperative blood transfusion and the prognosis of patients with gastric cancer is still unclear.A total 1581 who underwent curative gastrectomy from 2000 to 2008 were evaluated. Perioperative was defined as packed red cells within seven days before surgery, during or postoperative hospitalization period. evaluated using univariate multivariate Cox regression analyses.Of patients, 298 (19%) received transfusion. correlated older age (P < 0.001); larger tumor size...

10.1186/s12885-018-4574-4 article EN cc-by BMC Cancer 2018-06-11

C-terminal binding protein-2 (CtBP2), a transcriptional corepressor, has been reported to correlate with tumorigenesis and progression predict poor prognosis in several human cancers. However, few studies on CtBP2 gastric cancer (GC) have performed. In this research, we evaluated the correlations between expression clinicopathological characteristics, as well of GC patients. The effects silencing cells biology activity were also assessed. results showed that was overexpressed tissues closely...

10.18632/oncotarget.15661 article EN Oncotarget 2017-02-24

// Fei Wang 1,* , Ying Feng Peng Li 1 Kun 1,4 Liang Yi-Fei Liu 2 Hua Huang Yi-Bing Guo 3 Qin-Sheng Mao and Wan-Jiang Xue Department of General Surgery,Nantong University Affiliated Hospital, Nantong, Jiangsu, China Pathology,Nantong Surgical Comprehensive Laboratory, Nantong 4 Surgery, Changzhou Wujin People's Changzhou, * These authors have contributed equally to this work Correspondence to: Xue, email: Mao, Keywords : RASSF10, hepatocellular carcinoma, DNA methylation, tumor suppressor,...

10.18632/oncotarget.6654 article EN Oncotarget 2015-12-18

玉龙雪山寒温性云冷杉林动态监测样地的 物种组成及群落结构650201) 2 (玉龙雪山省级自然保护区管护局, 云南丽江 674100) 摘要: 云冷杉林是玉龙雪山东坡保存最完整的森林植被, 为了更好地了解其物种组成和群落结构等基本特征, 中 国科学院昆明植物研究所联合玉龙雪山省级自然保护区管护局, 按照CTFS (Center for Tropical Forest Science)的 样地建设标准, 于2012-2014年在玉龙雪山省级自然保护区内建立了25 ha (500 m × 500 m)的长期监测样地。本研 究以样地内所有胸径(DBH) ≥ 1 cm的木本植物(不含竹子)为研究对象

10.17520/biods.2016274 article KO Biodiversity Science 2017-01-01

The Cypripedium forrestii is an orchid species with extremely small populations (PSESP) in Yunnan, China. C. range-restricted and less-studied than many species, it exposed to various threats its survival. We investigated potential habitats collected 52 samples from eight locations, as well two outgroup for reference. developed genetic markers (SNPs) based on transcriptome sequencing (RNA-seq) data, analyzed the diversity, population structure, gene flow demographic history of detail. a...

10.3389/fpls.2024.1303625 article EN cc-by Frontiers in Plant Science 2024-01-31

Abstract Background &amp; Aims: Trichloroethylene (TCE) is a commonly used organic solvent in industry. Our previous studies have found that TCE can cause liver injury accompanied by macrophage polarization, but the specific mechanism unclear. The epigenetic regulation of polarization mainly focused on histone modification. Histone lysine demethylase 4A (KDM4A) involved activation macrophages. In this study, we mouse model investigated role KDM4A liversof TCE-drinking mice and expression...

10.21203/rs.3.rs-3323067/v1 preprint EN cc-by Research Square (Research Square) 2023-10-11

Abstract BACKGROUND: There are few studies of initial treatment and survival among elderly, newly diagnosed breast cancer (BC) patients stratified by receipt human epidermal growth factor receptor 2- (HER2-) targeted therapy. METHODS: Using linked Surveillance, Epidemiology, End Results (SEER) Medicare claims enrollment data from 2006-2009, women aged 65+ years with an incident diagnosis BC (index date) in 2007 no prior history any other were identified followed to evaluate survival. Study...

10.1158/0008-5472.sabcs13-p4-12-04 article EN Cancer Research 2013-12-15

Abstract Background: Angiogenesis plays an important role in the occurrence, development and metastasis of hepatocellular carcinoma (HCC). miR-378a-3p participates tumorigenesis tumor according to previous studies, yet exact it HCC angiogenesis remains poorly understood. Methods: qRT-PCR was used investigate expression tissues cell lines. The effects on vitro vivo were examined by CCK-8, transwell assay, tube formation matrigel plug assay. RNA sequencing, bioinformatics analysis, luciferase...

10.21203/rs.3.rs-581090/v1 preprint EN cc-by Research Square (Research Square) 2021-06-04
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