A5008800698- Sinusitis and nasal conditions
- Asthma and respiratory diseases
- Allergic Rhinitis and Sensitization
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Advanced Breast Cancer Therapies
- Advanced X-ray and CT Imaging
- HER2/EGFR in Cancer Research
- Breast Cancer Treatment Studies
- Gallbladder and Bile Duct Disorders
- Cancer-related Molecular Pathways
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Urologic and reproductive health conditions
- Hemodynamic Monitoring and Therapy
- Hip disorders and treatments
- Advanced MRI Techniques and Applications
- Genital Health and Disease
- Orthopaedic implants and arthroplasty
- Cardiac Imaging and Diagnostics
- Galectins and Cancer Biology
- Traditional Chinese Medicine Studies
- Infectious Diseases and Mycology
- Offshore Engineering and Technologies
- Intracranial Aneurysms: Treatment and Complications
First Hospital of Jilin University
2019-2024
Jilin University
2019-2024
Sichuan University
2024
Beijing Tongren Hospital
2018-2023
Capital Medical University
2018-2023
Beijing Institute of Neurosurgery
2018-2022
Baoji City Central Hospital
2022
Huazhong University of Science and Technology
2014-2021
Tongji Hospital
2014-2021
Peking Union Medical College Hospital
2019-2020
Recent studies have revealed that the nasal microbiota in patients with chronic rhinosinusitis polyps (CRSwNP) is profoundly altered and correlated systemic inflammation. However, little known regarding whether can be utilized to predict polyp recurrence. This study aimed determine constituents could used as biomarkers CRSwNP recurrence.Nasal were quantified characterized using bacterial 16S ribosomal RNA gene sequencing. Selected features for least absolute shrinkage selection operator...
Abstract Various methods are applied in the treatment of fresh and neglected Monteggia fractures. The purpose this retrospective study was to evaluate efficacy various methods, assess complexity associated with missed radial head dislocation. All fracture patients were reviewed between Jan 2012 Dec 2016. A detailed comparison made fractures diagnosis preliminary analysis clinical information from 1081 our center investigated, 42 included final analysis. group 25 an average Mayo Elbow...
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is a persistent sinonasal mucosa inflammatory disease. MicroRNAs (miRNAs) that are involved in the pathogenesis of CRSwNP Northern China remain unknown. Methods A miRCURY™ LNA Array was used to analyze miRNA profiles tissues patients (n = 19) and healthy controls 10). Subsequent pathways were predicted by DIANA‐mirPath software. Results Five upregulated miRNAs, including miR‐210‐5p, miR‐3178, miR‐585‐3p, miR‐3146, miR‐320e, 19...
Allergic rhinitis (AR) is an upper respiratory tract inflammation disease caused by IgE-mediated reactions against inhaled allergens. The incidence of AR significantly increasing throughout the world. Hence, more specific, and sensitive gene biomarkers understanding underlying pathways are necessary to further explore pathogenesis. To identify in nasal mucosa blood from patients which could be used diagnosis. expression profiles GSE43523 epithelial cells GSE75011 Th2-enriched CD4+ T were...
In sepsis patients, kidney damage is among the most dangerous complications, with a high mortality rate. addition, major adverse events within 30 days (MAKE30) served as comprehensive and unbiased clinical outcome measure for patients due to recent shift toward targeting patient-centered renal outcomes in research. However, underlying predictive model prediction of MAKE30 has not been reported any study. A cohort 2,849 from Medical Information Mart Intensive Care (MIMIC)-IV database was...
There is clinical evidence for impaired lung function in chronic rhinosinusitis with nasal polyps (CRSwNP) patients, which may be due to a high incidence of asthma comorbidity. The characteristics non-asthmatic CRSwNP patients are not known. Small airway dysfunction (SAD) involved the pathogenesis asthma. However, whether SAD detected CRSwNPs remains unclear.This study analysed and evaluated its relevance CRSwNPs.The data 191 consecutive (73 asthmatic 118 non-asthmatic) 30 control subjects...
Background The preoperative prediction of the recurrence chronic rhinosinusitis with nasal polyps (CRSwNP) remains difficult in clinical practice. Objective We aimed to develop a nomogram that combined peripheral risk factors clinically predict CRSwNP. Methods Data from 158 CRSwNP patients who underwent endoscopic sinus surgery (ESS) January 2012 December 2016 were collected, and followed up for 3 years. Of these, 96 ESS an earlier period formed training cohort development, 62 thereafter...
Background: Knowledge of the prevalence common sensitizing allergens may aid in overall management allergic disease a specified area. Objective:The aim this study was to identify and analyse inhaled food Beijing. Methods:This retrospective study, analysing demographic data serum sIgE antibody test results from 59057 outpatients who presented Beijing TongRen Hospital, January 2013 December 2019.Results: 28879 patients (48.9%) showed positive results; with significantly more males aged under...
Breast cancer is a prevalent and heterogeneous disease, with human epidermal growth factor receptor-2 (HER2) overexpression occurring in over 20% of cases. Poncirin, biologically active flavonone derived from the immature dried fruits Poncirus trifoliata, 7-O-neohesperidoside isosakuranetin well-documented history traditional Chinese medicine for its health-promoting properties. While previous research hinted at potential as an anticancer agent, specific effects on HER2 overexpressing breast...
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic sinonasal inflammatory disease limited treatment options of corticosteroids, sinus surgery, or both. CRSwNP frequently associated allergic rhinitis and asthma, but the molecular mechanisms underlying inflammation are not completely understood. We obtained four gene expression profiles ( GSE136825 , GSE36830 GSE23552 GSE72713 ) from Gene Expression Omnibus (GEO), which collectively included 65 polyp samples patients 54 mucosal...
Protein crystallization is a prevalent phenomenon existing in the formation of intricate protein-assembled structures living cells. Whether protein would exert specific biological function, however, remains poorly understood. Here, we reconstructed recombinant galectin-10 (gal-10) and artificially engineered gal-10 assembly two distinguishable states: i.e., an insoluble crystalline state soluble state. The potency either or to induce chemokine cytokine release primary human nasal epithelial...
To determine independent predictors of inguinal lymph node (ILN) metastasis in patients with penile cancer.We retrospectively analyzed all cancer who underwent surgery at our medical center the last ten years (n=157). Using univariate and multivariate logistic-regression models, we assessed associations age, medical-history, phimosis, onset-time, number maximum diameter involved ILNs measured by imaging, pathological T stage, degree tumor differentiation and/or cornification, lymphatic...
Objective To study the anatomical variations of origin uterine artery(UA)by three-dimensional(3D)reconstructed computed tomography angiography(CTA)and facilitate preoperative evaluation for gynecological surgeries or interventional therapies. Method The CTA findings 112 patients with an average age of(31.4±6.6)years old who had received a pelvic and undergone 3D reconstruction artery were retrospectively analyzed. Results volume was(95.6±26.8)cm 3.Of UA 224 sides,144 sides(64.3%)arose from...
The volumes of real-world graphs like knowledge graph are increasing rapidly, which makes streaming processing a hot research area. Processing in setting poses significant challenges from different perspectives, among partitioning method plays key role. Regarding query, well-designed is essential for achieving better performance. Existing offline methods often require full the graph, not possible during processing. In order to handle this problem, we propose an association-oriented named...